Action and toxicity of cyclosporine.

W. M. Bennett; D. J. Norman

doi:10.1146/annurev.me.37.020186.001243

Action and toxicity of cyclosporine.

W. M. Bennett, D. J. Norman

Research output: Contribution to journal › Review article › peer-review

150 Scopus citations

Abstract

Cyclosporine is a potent new immunosuppressive agent that has proven particularly useful in organ transplantation. The unique action of the drug on T-cell immunity without myelosuppression is summarized. Cyclosporine pharmacology and adverse reactions, particularly nephrotoxicity, are reviewed in this paper.

Original language	English (US)
Pages (from-to)	215-224
Number of pages	10
Journal	Annual review of medicine
Volume	37
DOIs	https://doi.org/10.1146/annurev.me.37.020186.001243
State	Published - 1986
Externally published	Yes

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1146/annurev.me.37.020186.001243

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title = "Action and toxicity of cyclosporine.",

abstract = "Cyclosporine is a potent new immunosuppressive agent that has proven particularly useful in organ transplantation. The unique action of the drug on T-cell immunity without myelosuppression is summarized. Cyclosporine pharmacology and adverse reactions, particularly nephrotoxicity, are reviewed in this paper.",

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year = "1986",

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AU - Bennett, W. M.

AU - Norman, D. J.

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AB - Cyclosporine is a potent new immunosuppressive agent that has proven particularly useful in organ transplantation. The unique action of the drug on T-cell immunity without myelosuppression is summarized. Cyclosporine pharmacology and adverse reactions, particularly nephrotoxicity, are reviewed in this paper.

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JO - Annual Review of Medicine

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ER -

Action and toxicity of cyclosporine.

Abstract

ASJC Scopus subject areas

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