Action and toxicity of cyclosporine.

W. M. Bennett; D. J. Norman

doi:10.1146/annurev.me.37.020186.001243

Action and toxicity of cyclosporine.

W. M. Bennett, D. J. Norman

Nephrology and Hypertension

Research output: Contribution to journal › Review article › peer-review

159 Scopus citations

Abstract

Cyclosporine is a potent new immunosuppressive agent that has proven particularly useful in organ transplantation. The unique action of the drug on T-cell immunity without myelosuppression is summarized. Cyclosporine pharmacology and adverse reactions, particularly nephrotoxicity, are reviewed in this paper.

Original language	English (US)
Pages (from-to)	215-224
Number of pages	10
Journal	Annual review of medicine
Volume	37
DOIs	https://doi.org/10.1146/annurev.me.37.020186.001243
State	Published - 1986

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1146/annurev.me.37.020186.001243

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title = "Action and toxicity of cyclosporine.",

abstract = "Cyclosporine is a potent new immunosuppressive agent that has proven particularly useful in organ transplantation. The unique action of the drug on T-cell immunity without myelosuppression is summarized. Cyclosporine pharmacology and adverse reactions, particularly nephrotoxicity, are reviewed in this paper.",

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AU - Bennett, W. M.

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AB - Cyclosporine is a potent new immunosuppressive agent that has proven particularly useful in organ transplantation. The unique action of the drug on T-cell immunity without myelosuppression is summarized. Cyclosporine pharmacology and adverse reactions, particularly nephrotoxicity, are reviewed in this paper.

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Action and toxicity of cyclosporine.

Abstract

ASJC Scopus subject areas

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