Acid–Base Status in Circulatory Failure

Bharat Dalvi, Alan Gilston, Thomas G. Deloughery, Ernest Benjamin, Andrew B. Leibowitz, Thomas J. Iberti, Horacio J. Adrogué, M. Nabil Rashad, Arnold B. Gorin, Joseph Yacoub, Nicolaos E. Madias, Howard L. Bleich

    Research output: Contribution to journalLetterpeer-review


    To the Editor: Adrogué et al. (May 18 issue)1 conclude that information about pH partial pressure of carbon dioxide (PCO2), or plasma bicarbonate level that is obtained from central venous blood (from the superior vena cava) is not different from that obtained from mixed venous blood (from the pulmonary artery). Although this may be true in persons who are hemodynamically and metabolically normal or nearly normal, it may not be true in patients with preexisting renal, pulmonary, or metabolic disease. A patient with chronic obstructive pulmonary disease in whom the effect of respiratory acidosis is compensated by the…

    Original languageEnglish (US)
    Pages (from-to)1611-1613
    Number of pages3
    JournalNew England Journal of Medicine
    Issue number23
    StatePublished - Dec 7 1989

    ASJC Scopus subject areas

    • Medicine(all)


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