Acetabular Insufficiency Fractures in the Setting of Graft vs Host Disease: A Report of Two Cases

Warren Nielsen; Kathryn Schabel

doi:10.1016/j.artd.2020.11.012

Acetabular Insufficiency Fractures in the Setting of Graft vs Host Disease: A Report of Two Cases

Warren Nielsen, Kathryn Schabel

Orthopaedics and Rehabilitation

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We report a case series of 2 patients with unilateral acetabular insufficiency fractures who received allogeneic peripheral blood stem cell transplantation for hematologic malignancies complicated by chronic graft vs host disease. These were managed with uncemented cup and cage total hip arthroplasty and stabilization of posterior column with plating. Osteonecrosis of the acetabulum is an uncommon musculoskeletal complication of chronic graft vs host disease. The orthopedic impact of this disease should not be overlooked. Surgical intervention with this construct can provide necessary stability to improve patient function.

Original language	English (US)
Pages (from-to)	54-59
Number of pages	6
Journal	Arthroplasty Today
Volume	7
DOIs	https://doi.org/10.1016/j.artd.2020.11.012
State	Published - Feb 2021

Keywords

Acetabular insufficiency
Arthroplasty
Avascular necrosis
Graft versus host disease
Osteonecrosis

ASJC Scopus subject areas

Surgery
Orthopedics and Sports Medicine

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10.1016/j.artd.2020.11.012

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title = "Acetabular Insufficiency Fractures in the Setting of Graft vs Host Disease: A Report of Two Cases",

abstract = "We report a case series of 2 patients with unilateral acetabular insufficiency fractures who received allogeneic peripheral blood stem cell transplantation for hematologic malignancies complicated by chronic graft vs host disease. These were managed with uncemented cup and cage total hip arthroplasty and stabilization of posterior column with plating. Osteonecrosis of the acetabulum is an uncommon musculoskeletal complication of chronic graft vs host disease. The orthopedic impact of this disease should not be overlooked. Surgical intervention with this construct can provide necessary stability to improve patient function.",

keywords = "Acetabular insufficiency, Arthroplasty, Avascular necrosis, Graft versus host disease, Osteonecrosis",

author = "Warren Nielsen and Kathryn Schabel",

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AB - We report a case series of 2 patients with unilateral acetabular insufficiency fractures who received allogeneic peripheral blood stem cell transplantation for hematologic malignancies complicated by chronic graft vs host disease. These were managed with uncemented cup and cage total hip arthroplasty and stabilization of posterior column with plating. Osteonecrosis of the acetabulum is an uncommon musculoskeletal complication of chronic graft vs host disease. The orthopedic impact of this disease should not be overlooked. Surgical intervention with this construct can provide necessary stability to improve patient function.

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KW - Avascular necrosis

KW - Graft versus host disease

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Acetabular Insufficiency Fractures in the Setting of Graft vs Host Disease: A Report of Two Cases

Abstract

Keywords

ASJC Scopus subject areas

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