Acellular cadaveric dermal matrix grafts for orbital wall reconstruction in patients with sinonasal malignancies

Rohan Verma, Allison J. Chen, Jennifer Murdock, Mathew Geltzeiler, Mark K. Wax, Roger A. Dailey, John D. Ng

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To describe the utilization of acellular cadaveric dermal matrix (ACDM) in patients undergoing orbital wall reconstruction after orbital preservation surgery for sinonasal malignancy. Methods: Retrospective case series of seven patients with sinonasal malignancy who had orbital reconstruction with ACDM implants from January 2012 to August 2020. Orbital preservation was performed in all patients with tumor extension up to and including periorbital. The main outcome measures were implant exposure, orbital infection, diplopia in primary gaze, enophthalmos, and eyelid malposition. Results: Patients ranged 37–78 years old (median: 66 years) and included 4 females and 3 males. The median follow-up time was 9 months (range 6–43 months) from the date of surgery. Squamous cell carcinoma comprised the majority of tumors with all patients needing medial wall reconstruction. Three patients received postoperative radiation therapy. No patients had any implant exposure, orbital infection, enophthalmos, or eyelid malposition. Conclusions: ACDM grafts can be used safely in orbital wall reconstruction in patients with sinonasal malignancies.

Original languageEnglish (US)
JournalOrbit (London)
DOIs
StateAccepted/In press - 2022
Externally publishedYes

Keywords

  • Acellular cadaveric dermal matrix (ACDM)
  • alloplastic implants
  • orbital wall reconstruction
  • sinonasal malignancy

ASJC Scopus subject areas

  • Ophthalmology

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