Abstract
Objective. The complex structural geometry of the right ventricle hinders accurate assessment of right ventricular volume and function on conventional two-dimensional echocardiography. We sought to evaluate the accuracy of real-time three-dimensional echocardiography for quantifying the volume of the right ventricle in an in vitro experimental study. Methods. We developed 39 anatomically accurate latex phantoms of human and porcine right ventricles (range, 24-108 mL) for 39 static and 10 pulsatile models. Real-time three-dimensional scanning was performed with the models placed in a water bath and with a 3.5-MHz probe. In the dynamic models a pulsatile flow pump generated 2 different stroke volumes (29 and 64 mL/beat). Static chamber volumes and stroke volumes were verified by water displacement, which served as a reference standard. Three-dimensional echo right ventricle volumes were determined by tracing derived B- and C-scans, using the Simpson rule. Results. Multiple regression analyses showed an excellent correlation between real-time three-dimensional echocardiographic determinations and the static volumes (B-scan, r = 0.99; C-scan, r = 0.98; P <.001), as well as stroke volumes in the dynamic model (B-scan, r = 0.90; C-scan, r = 0.86; P <.001). However, the C-scans tended to underestimate cavity and stroke volumes more than the B-scans (mean difference for static volume: B-scan, 1.4% ± 9.8%; C-scan, -7.4% ± 8.0%; P <.001; mean difference for stroke volumes: B-scan, 3.0% ± 19.1%; C-scan, -2.5% ± 20.9%; P <.001). Conclusions. Real-time three-dimensional echocardiography can accurately quantify right ventricle cavity volumes and stroke volumes without geometric assumptions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1069-1075 |
| Number of pages | 7 |
| Journal | Journal of Ultrasound in Medicine |
| Volume | 21 |
| Issue number | 10 |
| State | Published - Oct 1 2002 |
| Externally published | Yes |
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Keywords
- Congenital heart disease
- Right ventricle
- Three-dimensional sonography
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Radiological and Ultrasound Technology
- Acoustics and Ultrasonics
Cite this
Accuracy of real-time three-dimensional echocardiography for quantifying right ventricular volume : Static and pulsatile flow studies in an anatomic in vitro model. / Schindera, Sebastian T.; Mehwald, Petra S.; Sahn, David; Kececioglu, Deniz.
In: Journal of Ultrasound in Medicine, Vol. 21, No. 10, 01.10.2002, p. 1069-1075.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Accuracy of real-time three-dimensional echocardiography for quantifying right ventricular volume
T2 - Static and pulsatile flow studies in an anatomic in vitro model
AU - Schindera, Sebastian T.
AU - Mehwald, Petra S.
AU - Sahn, David
AU - Kececioglu, Deniz
PY - 2002/10/1
Y1 - 2002/10/1
N2 - Objective. The complex structural geometry of the right ventricle hinders accurate assessment of right ventricular volume and function on conventional two-dimensional echocardiography. We sought to evaluate the accuracy of real-time three-dimensional echocardiography for quantifying the volume of the right ventricle in an in vitro experimental study. Methods. We developed 39 anatomically accurate latex phantoms of human and porcine right ventricles (range, 24-108 mL) for 39 static and 10 pulsatile models. Real-time three-dimensional scanning was performed with the models placed in a water bath and with a 3.5-MHz probe. In the dynamic models a pulsatile flow pump generated 2 different stroke volumes (29 and 64 mL/beat). Static chamber volumes and stroke volumes were verified by water displacement, which served as a reference standard. Three-dimensional echo right ventricle volumes were determined by tracing derived B- and C-scans, using the Simpson rule. Results. Multiple regression analyses showed an excellent correlation between real-time three-dimensional echocardiographic determinations and the static volumes (B-scan, r = 0.99; C-scan, r = 0.98; P <.001), as well as stroke volumes in the dynamic model (B-scan, r = 0.90; C-scan, r = 0.86; P <.001). However, the C-scans tended to underestimate cavity and stroke volumes more than the B-scans (mean difference for static volume: B-scan, 1.4% ± 9.8%; C-scan, -7.4% ± 8.0%; P <.001; mean difference for stroke volumes: B-scan, 3.0% ± 19.1%; C-scan, -2.5% ± 20.9%; P <.001). Conclusions. Real-time three-dimensional echocardiography can accurately quantify right ventricle cavity volumes and stroke volumes without geometric assumptions.
AB - Objective. The complex structural geometry of the right ventricle hinders accurate assessment of right ventricular volume and function on conventional two-dimensional echocardiography. We sought to evaluate the accuracy of real-time three-dimensional echocardiography for quantifying the volume of the right ventricle in an in vitro experimental study. Methods. We developed 39 anatomically accurate latex phantoms of human and porcine right ventricles (range, 24-108 mL) for 39 static and 10 pulsatile models. Real-time three-dimensional scanning was performed with the models placed in a water bath and with a 3.5-MHz probe. In the dynamic models a pulsatile flow pump generated 2 different stroke volumes (29 and 64 mL/beat). Static chamber volumes and stroke volumes were verified by water displacement, which served as a reference standard. Three-dimensional echo right ventricle volumes were determined by tracing derived B- and C-scans, using the Simpson rule. Results. Multiple regression analyses showed an excellent correlation between real-time three-dimensional echocardiographic determinations and the static volumes (B-scan, r = 0.99; C-scan, r = 0.98; P <.001), as well as stroke volumes in the dynamic model (B-scan, r = 0.90; C-scan, r = 0.86; P <.001). However, the C-scans tended to underestimate cavity and stroke volumes more than the B-scans (mean difference for static volume: B-scan, 1.4% ± 9.8%; C-scan, -7.4% ± 8.0%; P <.001; mean difference for stroke volumes: B-scan, 3.0% ± 19.1%; C-scan, -2.5% ± 20.9%; P <.001). Conclusions. Real-time three-dimensional echocardiography can accurately quantify right ventricle cavity volumes and stroke volumes without geometric assumptions.
KW - Congenital heart disease
KW - Right ventricle
KW - Three-dimensional sonography
UR - http://www.scopus.com/inward/record.url?scp=0036788598&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036788598&partnerID=8YFLogxK
M3 - Article
C2 - 12369661
AN - SCOPUS:0036788598
VL - 21
SP - 1069
EP - 1075
JO - Journal of Ultrasound in Medicine
JF - Journal of Ultrasound in Medicine
SN - 0278-4297
IS - 10
ER -