Acceleration of growth in Turner syndrome patients treated with growth hormone: Summary of three-year results

Ronald (Ron) Rosenfeld

Research output: Contribution to journalArticle

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Abstract

In 1983, a multicenter, collaborative prospective study was begun to investigate the efficacy of human growth hormone (hGH), alone and in combination with oxandrolone, in girls with Turner syndrome. While subjects in the control group grew 3.8 cm/yr (-0.1 SD for untreated Turner patients), subjects receiving hGH alone grew 6.6, 5.4 and 4.6 cm/yr in years 1-3, respectively (+3.1, +2.0, +1.4 SD). Subjects in the combination therapy group grew 9.8, 7.4 and 6.1 cm/yr (+6.6, +4.3, +3.0 SD). Turner subjects in both treatment groups showed increased in Bayley-Pinneau predicted adult heights and in Turner projected adult heights.

Original languageEnglish (US)
Pages (from-to)49-51
Number of pages3
JournalJournal of Endocrinological Investigation
Volume12
Issue number8 SUPPL. 3
Publication statusPublished - 1989
Externally publishedYes

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ASJC Scopus subject areas

  • Endocrinology

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