Acceleration of allograft failure by cytomegalovirus

Research output: Contribution to journalArticle

89 Citations (Scopus)

Abstract

A number of human herpesviruses are important opportunistic pathogens that have been associated with increased morbidity and mortality in transplant recipients including human cytomegalovirus (HCMV), HHV6, HHV7, HHV8 as well as HSV-1, VZV. However, HCMV has been linked both epidemiologically and through the use of animal models to the acceleration of acute and chronic allograft rejection. This review will cover the pathophysiology, epidemiology, and mechanisms of CMV-associated disease in the setting of transplantation.

Original languageEnglish (US)
Pages (from-to)577-582
Number of pages6
JournalCurrent Opinion in Immunology
Volume19
Issue number5
DOIs
StatePublished - Oct 2007

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Cytomegalovirus
Allografts
Human Herpesvirus 6
Herpesviridae
Human Herpesvirus 1
Epidemiology
Animal Models
Transplantation
Morbidity
Mortality

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

Acceleration of allograft failure by cytomegalovirus. / Streblow, Daniel; Orloff, Susan; Nelson, Jay.

In: Current Opinion in Immunology, Vol. 19, No. 5, 10.2007, p. 577-582.

Research output: Contribution to journalArticle

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