Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop

Maisam Abu-El-Haija, Anna S. Gukovskaya, Dana K. Andersen, Timothy B. Gardner, Peter Hegyi, Stephen J. Pandol, Georgios I. Papachristou, Ashok K. Saluja, Vikesh K. Singh, Aliye Uc, Bechien U. Wu

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.

Original languageEnglish (US)
Pages (from-to)1185-1192
Number of pages8
JournalPancreas
Volume47
Issue number10
DOIs
StatePublished - Nov 1 2018

Keywords

  • acute pancreatitis
  • drug therapy
  • molecular targets
  • trials

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

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