Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop

Maisam Abu-El-Haija; Anna S. Gukovskaya; Dana K. Andersen; Timothy B. Gardner; Peter Hegyi; Stephen J. Pandol; Georgios I. Papachristou; Ashok K. Saluja; Vikesh K. Singh; Aliye Uc; Bechien U. Wu

doi:10.1097/MPA.0000000000001175

Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop

Maisam Abu-El-Haija, Anna S. Gukovskaya, Dana K. Andersen, Timothy B. Gardner, Peter Hegyi, Stephen J. Pandol, Georgios I. Papachristou, Ashok K. Saluja, Vikesh K. Singh, Aliye Uc, Bechien U. Wu

Gastroenterology and Hepatology

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.

Original language	English (US)
Pages (from-to)	1185-1192
Number of pages	8
Journal	Pancreas
Volume	47
Issue number	10
DOIs	https://doi.org/10.1097/MPA.0000000000001175
State	Published - Nov 1 2018

Keywords

acute pancreatitis
drug therapy
molecular targets
trials

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Hepatology
Endocrinology

Access to Document

10.1097/MPA.0000000000001175

Fingerprint

Dive into the research topics of 'Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop'. Together they form a unique fingerprint.

Cite this

Abu-El-Haija, M., Gukovskaya, A. S., Andersen, D. K., Gardner, T. B., Hegyi, P., Pandol, S. J., Papachristou, G. I., Saluja, A. K., Singh, V. K., Uc, A., & Wu, B. U. (2018). Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop. Pancreas, 47(10), 1185-1192. https://doi.org/10.1097/MPA.0000000000001175

Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop. / Abu-El-Haija, Maisam; Gukovskaya, Anna S.; Andersen, Dana K. et al.
In: Pancreas, Vol. 47, No. 10, 01.11.2018, p. 1185-1192.

Research output: Contribution to journal › Article › peer-review

Abu-El-Haija, M, Gukovskaya, AS, Andersen, DK, Gardner, TB, Hegyi, P, Pandol, SJ, Papachristou, GI, Saluja, AK, Singh, VK, Uc, A & Wu, BU 2018, 'Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop', Pancreas, vol. 47, no. 10, pp. 1185-1192. https://doi.org/10.1097/MPA.0000000000001175

Abu-El-Haija M, Gukovskaya AS, Andersen DK, Gardner TB, Hegyi P, Pandol SJ et al. Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop. Pancreas. 2018 Nov 1;47(10):1185-1192. doi: 10.1097/MPA.0000000000001175

@article{7d23efd90fcb4d8881e2f76368f977fb,

title = "Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop",

abstract = "A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.",

keywords = "acute pancreatitis, drug therapy, molecular targets, trials",

author = "Maisam Abu-El-Haija and Gukovskaya, {Anna S.} and Andersen, {Dana K.} and Gardner, {Timothy B.} and Peter Hegyi and Pandol, {Stephen J.} and Papachristou, {Georgios I.} and Saluja, {Ashok K.} and Singh, {Vikesh K.} and Aliye Uc and Wu, {Bechien U.}",

year = "2018",

month = nov,

day = "1",

doi = "10.1097/MPA.0000000000001175",

language = "English (US)",

volume = "47",

pages = "1185--1192",

journal = "Pancreas",

issn = "0885-3177",

publisher = "Lippincott Williams and Wilkins",

number = "10",

}

TY - JOUR

T1 - Accelerating the drug delivery pipeline for acute and chronic pancreatitis

T2 - Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop

AU - Abu-El-Haija, Maisam

AU - Gukovskaya, Anna S.

AU - Andersen, Dana K.

AU - Gardner, Timothy B.

AU - Hegyi, Peter

AU - Pandol, Stephen J.

AU - Papachristou, Georgios I.

AU - Saluja, Ashok K.

AU - Singh, Vikesh K.

AU - Uc, Aliye

AU - Wu, Bechien U.

PY - 2018/11/1

Y1 - 2018/11/1

N2 - A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.

AB - A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.

KW - acute pancreatitis

KW - drug therapy

KW - molecular targets

KW - trials

UR - http://www.scopus.com/inward/record.url?scp=85055080940&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85055080940&partnerID=8YFLogxK

U2 - 10.1097/MPA.0000000000001175

DO - 10.1097/MPA.0000000000001175

M3 - Article

C2 - 30325856

AN - SCOPUS:85055080940

SN - 0885-3177

VL - 47

SP - 1185

EP - 1192

JO - Pancreas

JF - Pancreas

IS - 10

ER -

Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this