Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop

Maisam Abu-El-Haija; Anna S. Gukovskaya; Dana K. Andersen; Timothy B. Gardner; Peter Hegyi; Stephen J. Pandol; Georgios I. Papachristou; Ashok K. Saluja; Vikesh K. Singh; Aliye Uc; Bechien U. Wu

doi:10.1097/MPA.0000000000001175

Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop

Maisam Abu-El-Haija, Anna S. Gukovskaya, Dana K. Andersen, Timothy B. Gardner, Peter Hegyi, Stephen J. Pandol, Georgios I. Papachristou, Ashok K. Saluja, Vikesh K. Singh, Aliye Uc, Bechien U. Wu

Gastroenterology

Research output: Contribution to journal › Article

6 Scopus citations

Abstract

A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.

Original language	English (US)
Pages (from-to)	1185-1192
Number of pages	8
Journal	Pancreas
Volume	47
Issue number	10
DOIs	https://doi.org/10.1097/MPA.0000000000001175
State	Published - Nov 1 2018

Keywords

acute pancreatitis
drug therapy
molecular targets
trials

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Hepatology
Endocrinology

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10.1097/MPA.0000000000001175

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Abu-El-Haija, M., Gukovskaya, A. S., Andersen, D. K., Gardner, T. B., Hegyi, P., Pandol, S. J., Papachristou, G. I., Saluja, A. K., Singh, V. K., Uc, A., & Wu, B. U. (2018). Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop. Pancreas, 47(10), 1185-1192. https://doi.org/10.1097/MPA.0000000000001175

Accelerating the drug delivery pipeline for acute and chronic pancreatitis : Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop. / Abu-El-Haija, Maisam; Gukovskaya, Anna S.; Andersen, Dana K.; Gardner, Timothy B.; Hegyi, Peter; Pandol, Stephen J.; Papachristou, Georgios I.; Saluja, Ashok K.; Singh, Vikesh K.; Uc, Aliye; Wu, Bechien U.

In: Pancreas, Vol. 47, No. 10, 01.11.2018, p. 1185-1192.

Research output: Contribution to journal › Article

Abu-El-Haija, M, Gukovskaya, AS, Andersen, DK, Gardner, TB, Hegyi, P, Pandol, SJ, Papachristou, GI, Saluja, AK, Singh, VK, Uc, A & Wu, BU 2018, 'Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop', Pancreas, vol. 47, no. 10, pp. 1185-1192. https://doi.org/10.1097/MPA.0000000000001175

Abu-El-Haija M, Gukovskaya AS, Andersen DK, Gardner TB, Hegyi P, Pandol SJ et al. Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop. Pancreas. 2018 Nov 1;47(10):1185-1192. https://doi.org/10.1097/MPA.0000000000001175

Abu-El-Haija, Maisam ; Gukovskaya, Anna S. ; Andersen, Dana K. ; Gardner, Timothy B. ; Hegyi, Peter ; Pandol, Stephen J. ; Papachristou, Georgios I. ; Saluja, Ashok K. ; Singh, Vikesh K. ; Uc, Aliye ; Wu, Bechien U. / Accelerating the drug delivery pipeline for acute and chronic pancreatitis : Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop. In: Pancreas. 2018 ; Vol. 47, No. 10. pp. 1185-1192.

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