@article{7d23efd90fcb4d8881e2f76368f977fb,
title = "Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop",
abstract = "A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.",
keywords = "acute pancreatitis, drug therapy, molecular targets, trials",
author = "Maisam Abu-El-Haija and Gukovskaya, {Anna S.} and Andersen, {Dana K.} and Gardner, {Timothy B.} and Peter Hegyi and Pandol, {Stephen J.} and Papachristou, {Georgios I.} and Saluja, {Ashok K.} and Singh, {Vikesh K.} and Aliye Uc and Wu, {Bechien U.}",
note = "Funding Information: V.S. is a consultant to Abbvie, Akcea Therapeutics, and Ariel Precision Medicine; A.U. is a member of American Board of Pediatrics, Subboard of Pediatric Gastroenterology; G.P. received grant support from Abbvie and is a consultant to GlaxoSmithKline and Abbvie. Funding Information: The authors thank the National Pancreas Foundation for the support, the members of the Food Drug Administration for consultation, and Ms. Joy Merusi of the University of Pittsburgh and Ms. Rachel Pisarski of The Scientific Consulting Group, Inc, for logistical support. Funding Information: The Hungarian National Research, Development and Innovation Office (K116634, KH125678). M.A.H, A.S.G., S.J.P., A.K.S., A.U., and B.U.W. acknowledge support from U01-108300 and others, which represent the Consortium for the Study of Pancreatitis, Diabetes and Pancreatic Cancer (CPDPC). M.A.H. is supported by NIDDK (Grant Number 1K23DK118190-01). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.",
year = "2018",
month = nov,
day = "1",
doi = "10.1097/MPA.0000000000001175",
language = "English (US)",
volume = "47",
pages = "1185--1192",
journal = "Pancreas",
issn = "0885-3177",
publisher = "Lippincott Williams and Wilkins",
number = "10",
}