Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop

Maisam Abu-El-Haija, Anna S. Gukovskaya, Dana Andersen, Timothy B. Gardner, Peter Hegyi, Stephen J. Pandol, Georgios I. Papachristou, Ashok K. Saluja, Vikesh K. Singh, Aliye Uc, Bechien U. Wu

Research output: Contribution to journalArticle

Abstract

A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.

LanguageEnglish (US)
Pages1185-1192
Number of pages8
JournalPancreas
Volume47
Issue number10
DOIs
StatePublished - Nov 1 2018

Fingerprint

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Chronic Pancreatitis
Pancreatitis
Education
Pharmaceutical Preparations
Natural History
Epidemiology
Clinical Trials
Therapeutics
Research

Keywords

  • acute pancreatitis
  • drug therapy
  • molecular targets
  • trials

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Hepatology
  • Endocrinology

Cite this

Accelerating the drug delivery pipeline for acute and chronic pancreatitis : Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop. / Abu-El-Haija, Maisam; Gukovskaya, Anna S.; Andersen, Dana; Gardner, Timothy B.; Hegyi, Peter; Pandol, Stephen J.; Papachristou, Georgios I.; Saluja, Ashok K.; Singh, Vikesh K.; Uc, Aliye; Wu, Bechien U.

In: Pancreas, Vol. 47, No. 10, 01.11.2018, p. 1185-1192.

Research output: Contribution to journalArticle

Abu-El-Haija, Maisam ; Gukovskaya, Anna S. ; Andersen, Dana ; Gardner, Timothy B. ; Hegyi, Peter ; Pandol, Stephen J. ; Papachristou, Georgios I. ; Saluja, Ashok K. ; Singh, Vikesh K. ; Uc, Aliye ; Wu, Bechien U. / Accelerating the drug delivery pipeline for acute and chronic pancreatitis : Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop. In: Pancreas. 2018 ; Vol. 47, No. 10. pp. 1185-1192.
@article{7d23efd90fcb4d8881e2f76368f977fb,
title = "Accelerating the drug delivery pipeline for acute and chronic pancreatitis: Summary of the working group on drug development and trials in acute pancreatitis at the National Institute of Diabetes and Digestive and Kidney Diseases workshop",
abstract = "A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.",
keywords = "acute pancreatitis, drug therapy, molecular targets, trials",
author = "Maisam Abu-El-Haija and Gukovskaya, {Anna S.} and Dana Andersen and Gardner, {Timothy B.} and Peter Hegyi and Pandol, {Stephen J.} and Papachristou, {Georgios I.} and Saluja, {Ashok K.} and Singh, {Vikesh K.} and Aliye Uc and Wu, {Bechien U.}",
year = "2018",
month = "11",
day = "1",
doi = "10.1097/MPA.0000000000001175",
language = "English (US)",
volume = "47",
pages = "1185--1192",
journal = "Pancreas",
issn = "0885-3177",
publisher = "Lippincott Williams and Wilkins",
number = "10",

}

TY - JOUR

T1 - Accelerating the drug delivery pipeline for acute and chronic pancreatitis

T2 - Pancreas

AU - Abu-El-Haija, Maisam

AU - Gukovskaya, Anna S.

AU - Andersen, Dana

AU - Gardner, Timothy B.

AU - Hegyi, Peter

AU - Pandol, Stephen J.

AU - Papachristou, Georgios I.

AU - Saluja, Ashok K.

AU - Singh, Vikesh K.

AU - Uc, Aliye

AU - Wu, Bechien U.

PY - 2018/11/1

Y1 - 2018/11/1

N2 - A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.

AB - A workshop was sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases to focus on research gaps and opportunities on drug development for pancreatitis. This conference was held on July 25, 2018, and structured into 3 working groups (WG): Acute pancreatitis (AP) WG, recurrent AP WG, and chronic pancreatitis WG. This article reports the outcome of the work accomplished by the AP WG to provide the natural history, epidemiology, and current management of AP; inform about the role of preclinical models in therapy selection; and discuss clinical trial designs with clinical and patient-reported outcomes to test new therapies.

KW - acute pancreatitis

KW - drug therapy

KW - molecular targets

KW - trials

UR - http://www.scopus.com/inward/record.url?scp=85055080940&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85055080940&partnerID=8YFLogxK

U2 - 10.1097/MPA.0000000000001175

DO - 10.1097/MPA.0000000000001175

M3 - Article

VL - 47

SP - 1185

EP - 1192

JO - Pancreas

JF - Pancreas

SN - 0885-3177

IS - 10

ER -