Abundant hepatic gaucher-like cells following chemotherapy and bone marrow transplantation for hematologic malignancy: Report of two cases

Peter Stenzel, Douglas A. Weeks

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Cells with a resemblance to Gaucher cells, sometimes called pseudo-Gaucher cells, are seen in the bone marrow of some patients with hematologic malignancy or anemia. These cells are derived from cells of the monocytic lineage but do not show the characteristic inclusions of true Gaucher cells when examined by electron microscopy. Large numbers of Gaucher-like cells were found in the livers at autopsy of 2 patients with hematologic malignancy treated with chemotherapy and bone marrow transplant. Knowledge of this phenomenon may be useful in the interpretation of liver biopsy done on a patient with bone marrow transplant.

Original languageEnglish (US)
Pages (from-to)89-92
Number of pages4
JournalInternational Journal of Surgical Pathology
Volume21
Issue number1
DOIs
StatePublished - Feb 1 2013

Keywords

  • Gaucher-like cells
  • bone marrow transplant
  • liver
  • pseudo-Gaucher

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine

Fingerprint Dive into the research topics of 'Abundant hepatic gaucher-like cells following chemotherapy and bone marrow transplantation for hematologic malignancy: Report of two cases'. Together they form a unique fingerprint.

Cite this