Abnormal scleral findings in uveal effusion syndrome

Robert C. Ward, Evangelos S. Gragoudas, David M. Pon, Daniel Albert

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

We successfully treated a patient with uveal effusion syndrome and abnormal sclera with a partial-thickness sclerectomy. Part of the sclera was immediately cultured, and the excised sclera and the cultured cells were examined by electron microscopy. The sclera demonstrated increased glycosaminoglycan-like deposits between the scleral fibers. The cultured scleral cells showed large intracellular glycogen-like deposits, which were not seen in cells cultured from two control scleras. These findings may be the result of a metabolic defect, which causes a thick, impermeable sclera in some cases of uveal effusion.

Original languageEnglish (US)
Pages (from-to)139-146
Number of pages8
JournalAmerican journal of ophthalmology
Volume106
Issue number2
DOIs
StatePublished - Aug 15 1988
Externally publishedYes

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Sclera
Cultured Cells
Glycosaminoglycans
Glycogen
Electron Microscopy

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Abnormal scleral findings in uveal effusion syndrome. / Ward, Robert C.; Gragoudas, Evangelos S.; Pon, David M.; Albert, Daniel.

In: American journal of ophthalmology, Vol. 106, No. 2, 15.08.1988, p. 139-146.

Research output: Contribution to journalArticle

Ward, Robert C. ; Gragoudas, Evangelos S. ; Pon, David M. ; Albert, Daniel. / Abnormal scleral findings in uveal effusion syndrome. In: American journal of ophthalmology. 1988 ; Vol. 106, No. 2. pp. 139-146.
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