Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice

Agriculture & Biology

• muscular diseases 100%
• fibrillins 90%
• muscles 48%
• mice 42%
• white adipose tissue 35%
• forelimbs 33%
• muscular dystrophy 24%
• genetic rescue 15%
• musculoskeletal diseases 14%
• mutation 12%
• contracture 12%
• myosin heavy chains 11%
• recessive genes 11%
• muscle development 11%
• creatine kinase 10%
• hypertrophy 9%
• myosin 9%
• muscle tissues 9%
• histology 9%
• connective tissues 9%
• skeletal muscle 8%
• death 7%
• genes 6%
• alleles 6%
• phenotype 6%
• tissues 4%

Medicine & Life Sciences

• Muscular Diseases 80%
• Fibrillin-2 66%
• Muscles 44%
• White Adipose Tissue 33%
• Forelimb 33%
• Muscular Dystrophies 22%
• Congenital contractural arachnodactyly 17%
• Fibrillins 14%
• Fibrillin-1 14%
• Microfibrils 13%
• Recessive Genes 13%
• Marfan Syndrome 11%
• Myosin Heavy Chains 11%
• Muscle Development 10%
• Perinatal Death 10%
• Mutation 10%
• Myosins 10%
• Contracture 10%
• Muscle Weakness 9%
• Creatine Kinase 9%
• Connective Tissue 8%
• Respiratory Insufficiency 8%
• Hypertrophy 8%
• Genes 7%
• Skeletal Muscle 7%
• Histology 7%
• Alleles 6%
• Phenotype 5%
• Wounds and Injuries 4%
• In Vitro Techniques 4%

Earth & Environmental Sciences

• muscle 65%
• fat 20%
• tissue 14%
• mutation 13%
• defect 11%
• histology 8%
• allele 7%
• abnormality 7%
• phenotype 7%
• loss 3%