Aberrant epigenetic silencing is triggered by a transient reduction in gene expression

Jon A. Oyer; Adrian Chu; Sukhmani Brar; Mitchell S. Turker

doi:10.1201/b16304

Aberrant epigenetic silencing is triggered by a transient reduction in gene expression

Jon A. Oyer, Adrian Chu, Sukhmani Brar, Mitchell S. Turker

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Many models designed to examine initiation of silencing track normal epigenetic changes during development at imprinted genes [7] or during X chromosome inactivation [8], but developmentally programmed silencing may progress differently than aberrant silencing occurring in cancer.

Original language	English (US)
Title of host publication	Epigenetics and Pathology
Subtitle of host publication	Exploring Connections between Genetic Mechanisms and Disease Expression
Publisher	Apple Academic Press
Pages	173-200
Number of pages	28
ISBN (Electronic)	9781482224825
ISBN (Print)	9781926895789
DOIs	https://doi.org/10.1201/b16304
State	Published - Jan 1 2013

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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title = "Aberrant epigenetic silencing is triggered by a transient reduction in gene expression",

abstract = "Many models designed to examine initiation of silencing track normal epigenetic changes during development at imprinted genes [7] or during X chromosome inactivation [8], but developmentally programmed silencing may progress differently than aberrant silencing occurring in cancer.",

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Aberrant epigenetic silencing is triggered by a transient reduction in gene expression

Abstract

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