Aberrant epigenetic silencing is triggered by a transient reduction in gene expression

Jon A. Oyer, Adrian Chu, Sukhmani Brar, Mitchell Turker

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Many models designed to examine initiation of silencing track normal epigenetic changes during development at imprinted genes [7] or during X chromosome inactivation [8], but developmentally programmed silencing may progress differently than aberrant silencing occurring in cancer.

Original languageEnglish (US)
Title of host publicationEpigenetics and Pathology
Subtitle of host publicationExploring Connections between Genetic Mechanisms and Disease Expression
PublisherApple Academic Press
Pages173-200
Number of pages28
ISBN (Electronic)9781482224825
ISBN (Print)9781926895789
DOIs
StatePublished - Jan 1 2013

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Oyer, J. A., Chu, A., Brar, S., & Turker, M. (2013). Aberrant epigenetic silencing is triggered by a transient reduction in gene expression. In Epigenetics and Pathology: Exploring Connections between Genetic Mechanisms and Disease Expression (pp. 173-200). Apple Academic Press. https://doi.org/10.1201/b16304