Aberrant epigenetic silencing is triggered by a transient reduction in gene expression

Jon A. Oyer, Adrian Chu, Sukhmani Brar, Mitchell Turker

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Many models designed to examine initiation of silencing track normal epigenetic changes during development at imprinted genes [7] or during X chromosome inactivation [8], but developmentally programmed silencing may progress differently than aberrant silencing occurring in cancer.

Original languageEnglish (US)
Title of host publicationEpigenetics and Pathology
Subtitle of host publicationExploring Connections between Genetic Mechanisms and Disease Expression
PublisherApple Academic Press
Pages173-200
Number of pages28
ISBN (Electronic)9781482224825
ISBN (Print)9781926895789
DOIs
StatePublished - Jan 1 2013

Fingerprint

X Chromosome Inactivation
Chromosomes, Human, Pair 8
Chromosomes
Epigenomics
Gene expression
Genes
Gene Expression
Neoplasms

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Oyer, J. A., Chu, A., Brar, S., & Turker, M. (2013). Aberrant epigenetic silencing is triggered by a transient reduction in gene expression. In Epigenetics and Pathology: Exploring Connections between Genetic Mechanisms and Disease Expression (pp. 173-200). Apple Academic Press. https://doi.org/10.1201/b16304

Aberrant epigenetic silencing is triggered by a transient reduction in gene expression. / Oyer, Jon A.; Chu, Adrian; Brar, Sukhmani; Turker, Mitchell.

Epigenetics and Pathology: Exploring Connections between Genetic Mechanisms and Disease Expression. Apple Academic Press, 2013. p. 173-200.

Research output: Chapter in Book/Report/Conference proceedingChapter

Oyer, JA, Chu, A, Brar, S & Turker, M 2013, Aberrant epigenetic silencing is triggered by a transient reduction in gene expression. in Epigenetics and Pathology: Exploring Connections between Genetic Mechanisms and Disease Expression. Apple Academic Press, pp. 173-200. https://doi.org/10.1201/b16304
Oyer JA, Chu A, Brar S, Turker M. Aberrant epigenetic silencing is triggered by a transient reduction in gene expression. In Epigenetics and Pathology: Exploring Connections between Genetic Mechanisms and Disease Expression. Apple Academic Press. 2013. p. 173-200 https://doi.org/10.1201/b16304
Oyer, Jon A. ; Chu, Adrian ; Brar, Sukhmani ; Turker, Mitchell. / Aberrant epigenetic silencing is triggered by a transient reduction in gene expression. Epigenetics and Pathology: Exploring Connections between Genetic Mechanisms and Disease Expression. Apple Academic Press, 2013. pp. 173-200
@inbook{037492c4515f41aea4c3e0662180c9cd,
title = "Aberrant epigenetic silencing is triggered by a transient reduction in gene expression",
abstract = "Many models designed to examine initiation of silencing track normal epigenetic changes during development at imprinted genes [7] or during X chromosome inactivation [8], but developmentally programmed silencing may progress differently than aberrant silencing occurring in cancer.",
author = "Oyer, {Jon A.} and Adrian Chu and Sukhmani Brar and Mitchell Turker",
year = "2013",
month = "1",
day = "1",
doi = "10.1201/b16304",
language = "English (US)",
isbn = "9781926895789",
pages = "173--200",
booktitle = "Epigenetics and Pathology",
publisher = "Apple Academic Press",

}

TY - CHAP

T1 - Aberrant epigenetic silencing is triggered by a transient reduction in gene expression

AU - Oyer, Jon A.

AU - Chu, Adrian

AU - Brar, Sukhmani

AU - Turker, Mitchell

PY - 2013/1/1

Y1 - 2013/1/1

N2 - Many models designed to examine initiation of silencing track normal epigenetic changes during development at imprinted genes [7] or during X chromosome inactivation [8], but developmentally programmed silencing may progress differently than aberrant silencing occurring in cancer.

AB - Many models designed to examine initiation of silencing track normal epigenetic changes during development at imprinted genes [7] or during X chromosome inactivation [8], but developmentally programmed silencing may progress differently than aberrant silencing occurring in cancer.

UR - http://www.scopus.com/inward/record.url?scp=85054693390&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85054693390&partnerID=8YFLogxK

U2 - 10.1201/b16304

DO - 10.1201/b16304

M3 - Chapter

AN - SCOPUS:85054693390

SN - 9781926895789

SP - 173

EP - 200

BT - Epigenetics and Pathology

PB - Apple Academic Press

ER -