Abstract
A mutant Rauscher spleen focus-forming virus (mutant 4-3) that causes mild splenic erythroblastoma in mice has a 44-base-pair deletion in the 3' region of its envelope glycoprotein (env) gene. The encoded glycoprotein terminates prematurely, lacks a hydrophobic membrane anchor, and has a shortened intracellular lifespan. An active site for causing erythroblast proliferation may occur in the undamaged amino-terminal domain of the env glycoprotein.
Original language | English (US) |
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Pages (from-to) | 990-993 |
Number of pages | 4 |
Journal | Journal of virology |
Volume | 53 |
Issue number | 3 |
DOIs | |
State | Published - 1985 |
Externally published | Yes |
ASJC Scopus subject areas
- Microbiology
- Immunology
- Insect Science
- Virology