A tissue-specific endothelial cell molecule involved in lymphocyte homing

Philip Streeter, Ellen Lakey Berg, Bich Tien N Rouse, Robert F. Bargatze, Eugene C. Butcher

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Abstract

An endothelial cell surface molecule that is selectively expressed in mucosal organs is required for lymphocyte homing to mucosal lymphoid tissues. This 'vascular addressin' appears to function as a tissue-specific marker or address signal for recognition by lymphocytes circulating in the blood.

Original languageEnglish (US)
Pages (from-to)41-46
Number of pages6
JournalNature
Volume331
Issue number6151
Publication statusPublished - 1988
Externally publishedYes

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Cite this

Streeter, P., Berg, E. L., Rouse, B. T. N., Bargatze, R. F., & Butcher, E. C. (1988). A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature, 331(6151), 41-46.