A tissue-specific endothelial cell molecule involved in lymphocyte homing

Philip R. Streeter, Ellen Lakey Berg, Bich Tien N. Rouse, Robert F. Bargatze, Eugene C. Butcher

Research output: Contribution to journalArticle

594 Scopus citations

Abstract

An endothelial cell surface molecule that is selectively expressed in mucosal organs is required for lymphocyte homing to mucosal lymphoid tissues. This 'vascular addressin' appears to function as a tissue-specific marker or address signal for recognition by lymphocytes circulating in the blood.

Original languageEnglish (US)
Pages (from-to)41-46
Number of pages6
JournalNature
Volume331
Issue number6151
DOIs
StatePublished - Jan 1 1988

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    Streeter, P. R., Berg, E. L., Rouse, B. T. N., Bargatze, R. F., & Butcher, E. C. (1988). A tissue-specific endothelial cell molecule involved in lymphocyte homing. Nature, 331(6151), 41-46. https://doi.org/10.1038/331041a0