A Time and a Place for Nkx2-1 in Interneuron Specification and Migration

Laura A B Elias, Gregory Potter, Arnold R. Kriegstein

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The homeobox transcription factor, Nkx2-1, plays multiple roles during forebrain development. Using restricted genetic ablation of Nkx2-1, in this issue of Neuron, Butt et al. show that Nkx2-1 in telencephalic progenitors regulates interneuron subtype specification, while Nóbrega-Pereira et al. demonstrate that postmitotic Nkx2-1 regulates migration and sorting of interneurons to the striatum or cortex by controlling the expression of the guidance receptor, Neuropilin-2.

Original languageEnglish (US)
Pages (from-to)679-682
Number of pages4
JournalNeuron
Volume59
Issue number5
DOIs
StatePublished - Sep 11 2008
Externally publishedYes

Fingerprint

Interneurons
Neuropilin-2
Telencephalon
Homeobox Genes
Prosencephalon
Transcription Factors
Neurons

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

A Time and a Place for Nkx2-1 in Interneuron Specification and Migration. / Elias, Laura A B; Potter, Gregory; Kriegstein, Arnold R.

In: Neuron, Vol. 59, No. 5, 11.09.2008, p. 679-682.

Research output: Contribution to journalArticle

Elias, Laura A B ; Potter, Gregory ; Kriegstein, Arnold R. / A Time and a Place for Nkx2-1 in Interneuron Specification and Migration. In: Neuron. 2008 ; Vol. 59, No. 5. pp. 679-682.
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