TY - JOUR
T1 - A Time and a Place for Nkx2-1 in Interneuron Specification and Migration
AU - Elias, Laura A.B.
AU - Potter, Gregory B.
AU - Kriegstein, Arnold R.
PY - 2008/9/11
Y1 - 2008/9/11
N2 - The homeobox transcription factor, Nkx2-1, plays multiple roles during forebrain development. Using restricted genetic ablation of Nkx2-1, in this issue of Neuron, Butt et al. show that Nkx2-1 in telencephalic progenitors regulates interneuron subtype specification, while Nóbrega-Pereira et al. demonstrate that postmitotic Nkx2-1 regulates migration and sorting of interneurons to the striatum or cortex by controlling the expression of the guidance receptor, Neuropilin-2.
AB - The homeobox transcription factor, Nkx2-1, plays multiple roles during forebrain development. Using restricted genetic ablation of Nkx2-1, in this issue of Neuron, Butt et al. show that Nkx2-1 in telencephalic progenitors regulates interneuron subtype specification, while Nóbrega-Pereira et al. demonstrate that postmitotic Nkx2-1 regulates migration and sorting of interneurons to the striatum or cortex by controlling the expression of the guidance receptor, Neuropilin-2.
UR - http://www.scopus.com/inward/record.url?scp=50849088323&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=50849088323&partnerID=8YFLogxK
U2 - 10.1016/j.neuron.2008.08.017
DO - 10.1016/j.neuron.2008.08.017
M3 - Short survey
C2 - 18786351
AN - SCOPUS:50849088323
SN - 0896-6273
VL - 59
SP - 679
EP - 682
JO - Neuron
JF - Neuron
IS - 5
ER -