A Tale of Two Metals

Research output: Contribution to journalShort survey

5 Scopus citations

Abstract

A recent study by Thomas O'Halloran and his group at Northwestern University (Avarez et al. Sciencexpress, www.scienceexpress.org, 26 November 2009) has provided insights into how tetrathiomolybdate inhibits copper-trafficking proteins through metal cluster formation. The broader context of the work provides an attractive explanation of the long recognized but poorly understood antagonistic effects of Mo and Cu in living organisms.

Original languageEnglish (US)
Pages (from-to)8-9
Number of pages2
JournalChemistry and Biology
Volume17
Issue number1
DOIs
StatePublished - Jan 29 2010

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ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry

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