Abstract
A recent study by Thomas O'Halloran and his group at Northwestern University (Avarez et al. Sciencexpress, www.scienceexpress.org, 26 November 2009) has provided insights into how tetrathiomolybdate inhibits copper-trafficking proteins through metal cluster formation. The broader context of the work provides an attractive explanation of the long recognized but poorly understood antagonistic effects of Mo and Cu in living organisms.
Original language | English (US) |
---|---|
Pages (from-to) | 8-9 |
Number of pages | 2 |
Journal | Chemistry and Biology |
Volume | 17 |
Issue number | 1 |
DOIs | |
State | Published - Jan 29 2010 |
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ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Molecular Biology
- Clinical Biochemistry
- Molecular Medicine
- Pharmacology
Cite this
A Tale of Two Metals. / Blackburn, Ninian.
In: Chemistry and Biology, Vol. 17, No. 1, 29.01.2010, p. 8-9.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A Tale of Two Metals
AU - Blackburn, Ninian
PY - 2010/1/29
Y1 - 2010/1/29
N2 - A recent study by Thomas O'Halloran and his group at Northwestern University (Avarez et al. Sciencexpress, www.scienceexpress.org, 26 November 2009) has provided insights into how tetrathiomolybdate inhibits copper-trafficking proteins through metal cluster formation. The broader context of the work provides an attractive explanation of the long recognized but poorly understood antagonistic effects of Mo and Cu in living organisms.
AB - A recent study by Thomas O'Halloran and his group at Northwestern University (Avarez et al. Sciencexpress, www.scienceexpress.org, 26 November 2009) has provided insights into how tetrathiomolybdate inhibits copper-trafficking proteins through metal cluster formation. The broader context of the work provides an attractive explanation of the long recognized but poorly understood antagonistic effects of Mo and Cu in living organisms.
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U2 - 10.1016/j.chembiol.2010.01.004
DO - 10.1016/j.chembiol.2010.01.004
M3 - Article
C2 - 20142035
AN - SCOPUS:75149157575
VL - 17
SP - 8
EP - 9
JO - Cell Chemical Biology
JF - Cell Chemical Biology
SN - 2451-9448
IS - 1
ER -