A systematic review of intracranial chondrosarcoma and survival

Orin G. Bloch, Brian J. Jian, Isaac Yang, Seunggu J. Han, Derick Aranda, Brian J. Ahn, Andrew T. Parsa

Research output: Contribution to journalReview article

81 Scopus citations

Abstract

Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A systematic review was performed to study the relationship between potential prognostic factors and survival. The survival rates were analyzed according to modality of treatment, treatment history, histological subtype, and histological grade. A total of 560 patients with intracranial chondrosarcoma were analyzed. Median follow-up time was 60 months. The 5-year mortality among all patients was 11.5% with median survival of 24 months. Mortality at 5 years was significantly greater for patients with tumors of higher grade, or of the mesenchymal subtype, or who had received surgical resection alone. The results of our systematic review provide useful data in predicting survival among intracranial chondrosarcoma patients.

Original languageEnglish (US)
Pages (from-to)1547-1551
Number of pages5
JournalJournal of Clinical Neuroscience
Volume16
Issue number12
DOIs
StatePublished - Dec 2009

Keywords

  • Cranial chondrosarcoma
  • Survival outcomes
  • Systematic review

ASJC Scopus subject areas

  • Surgery
  • Neurology
  • Clinical Neurology
  • Physiology (medical)

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    Bloch, O. G., Jian, B. J., Yang, I., Han, S. J., Aranda, D., Ahn, B. J., & Parsa, A. T. (2009). A systematic review of intracranial chondrosarcoma and survival. Journal of Clinical Neuroscience, 16(12), 1547-1551. https://doi.org/10.1016/j.jocn.2009.05.003