A systematic review of intracranial chondrosarcoma and survival

Orin G. Bloch; Brian J. Jian; Isaac Yang; Seunggu J. Han; Derick Aranda; Brian J. Ahn; Andrew T. Parsa

doi:10.1016/j.jocn.2009.05.003

A systematic review of intracranial chondrosarcoma and survival

Orin G. Bloch, Brian J. Jian, Isaac Yang, Seunggu J. Han, Derick Aranda, Brian J. Ahn, Andrew T. Parsa

Research output: Contribution to journal › Review article › peer-review

128 Scopus citations

Abstract

Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A systematic review was performed to study the relationship between potential prognostic factors and survival. The survival rates were analyzed according to modality of treatment, treatment history, histological subtype, and histological grade. A total of 560 patients with intracranial chondrosarcoma were analyzed. Median follow-up time was 60 months. The 5-year mortality among all patients was 11.5% with median survival of 24 months. Mortality at 5 years was significantly greater for patients with tumors of higher grade, or of the mesenchymal subtype, or who had received surgical resection alone. The results of our systematic review provide useful data in predicting survival among intracranial chondrosarcoma patients.

Original language	English (US)
Pages (from-to)	1547-1551
Number of pages	5
Journal	Journal of Clinical Neuroscience
Volume	16
Issue number	12
DOIs	https://doi.org/10.1016/j.jocn.2009.05.003
State	Published - Dec 2009
Externally published	Yes

Keywords

Cranial chondrosarcoma
Survival outcomes
Systematic review

ASJC Scopus subject areas

Surgery
Neurology
Clinical Neurology
Physiology (medical)

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10.1016/j.jocn.2009.05.003

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title = "A systematic review of intracranial chondrosarcoma and survival",

abstract = "Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A systematic review was performed to study the relationship between potential prognostic factors and survival. The survival rates were analyzed according to modality of treatment, treatment history, histological subtype, and histological grade. A total of 560 patients with intracranial chondrosarcoma were analyzed. Median follow-up time was 60 months. The 5-year mortality among all patients was 11.5% with median survival of 24 months. Mortality at 5 years was significantly greater for patients with tumors of higher grade, or of the mesenchymal subtype, or who had received surgical resection alone. The results of our systematic review provide useful data in predicting survival among intracranial chondrosarcoma patients.",

keywords = "Cranial chondrosarcoma, Survival outcomes, Systematic review",

author = "Bloch, {Orin G.} and Jian, {Brian J.} and Isaac Yang and Han, {Seunggu J.} and Derick Aranda and Ahn, {Brian J.} and Parsa, {Andrew T.}",

note = "Funding Information: The authors gratefully acknowledge the following sources of support: IY was partially supported by a UCSF Clinical and Translational Scientist Training Research Award and a NIH National Research Service Award grant. SJH was funded by a Howard Hughes Medical Institute Research Training Fellowship. ATP the senior author is partially funded by a Reza and Georgianna Khatib Endowed Chair in Skull Base Tumor Surgery.",

year = "2009",

month = dec,

doi = "10.1016/j.jocn.2009.05.003",

language = "English (US)",

volume = "16",

pages = "1547--1551",

journal = "Journal of Clinical Neuroscience",

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T1 - A systematic review of intracranial chondrosarcoma and survival

AU - Bloch, Orin G.

AU - Jian, Brian J.

AU - Yang, Isaac

AU - Han, Seunggu J.

AU - Aranda, Derick

AU - Ahn, Brian J.

AU - Parsa, Andrew T.

N1 - Funding Information: The authors gratefully acknowledge the following sources of support: IY was partially supported by a UCSF Clinical and Translational Scientist Training Research Award and a NIH National Research Service Award grant. SJH was funded by a Howard Hughes Medical Institute Research Training Fellowship. ATP the senior author is partially funded by a Reza and Georgianna Khatib Endowed Chair in Skull Base Tumor Surgery.

PY - 2009/12

Y1 - 2009/12

N2 - Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A systematic review was performed to study the relationship between potential prognostic factors and survival. The survival rates were analyzed according to modality of treatment, treatment history, histological subtype, and histological grade. A total of 560 patients with intracranial chondrosarcoma were analyzed. Median follow-up time was 60 months. The 5-year mortality among all patients was 11.5% with median survival of 24 months. Mortality at 5 years was significantly greater for patients with tumors of higher grade, or of the mesenchymal subtype, or who had received surgical resection alone. The results of our systematic review provide useful data in predicting survival among intracranial chondrosarcoma patients.

AB - Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A systematic review was performed to study the relationship between potential prognostic factors and survival. The survival rates were analyzed according to modality of treatment, treatment history, histological subtype, and histological grade. A total of 560 patients with intracranial chondrosarcoma were analyzed. Median follow-up time was 60 months. The 5-year mortality among all patients was 11.5% with median survival of 24 months. Mortality at 5 years was significantly greater for patients with tumors of higher grade, or of the mesenchymal subtype, or who had received surgical resection alone. The results of our systematic review provide useful data in predicting survival among intracranial chondrosarcoma patients.

KW - Cranial chondrosarcoma

KW - Survival outcomes

KW - Systematic review

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JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

IS - 12

ER -

A systematic review of intracranial chondrosarcoma and survival

Abstract

Keywords

ASJC Scopus subject areas

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