A statistical model and simulator for cardiovascular pressure signals

C. Staats, Daniel Austin, M. Aboy

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Physiological signal simulators are often used to conduct validation studies of commercially available devices such as oscillometric non-invasive blood pressure (NIBP) monitors. Numerous assessment studies have been conducted using simulators to validate commercial NIBP monitors. While there are several simulators commercially available to evaluate oscillometric NIBP devices, currently there are no simulators designed to validate invasive pressure signal devices. A statistical model and simulator for invasive cardiovascular pressure signals such as arterial blood pressure and intracranial pressure are described. The model incorporates the effects of respiration on pressure signals and can be used to generate synthetic signals with time and frequency domain characteristics matching any desired subject population. Additionally, the way that noise and artefacts typically present in real pressure signals should be modelled is described. The proposed statistical model is a useful tool for validation of algorithms designed to process or analyse biomedical pressure signals to estimate parameters of clinical interest such as the cardiac frequency, heart rate variability, respiratory frequency, and pulse pressure variation in the presence of noise. The model can be used to simulate signals in order to validate commercial devices that process and analyse invasive pressure signals.

Original languageEnglish (US)
Pages (from-to)991-998
Number of pages8
JournalProceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
Volume222
Issue number6
DOIs
StatePublished - Jun 1 2008

Fingerprint

Statistical Models
Blood pressure
Simulators
Pressure
Blood Pressure Monitors
Equipment and Supplies
Noise
Blood Pressure
Validation Studies
Intracranial Pressure
Artifacts
Arterial Pressure
Respiration
Heart Rate
Population

Keywords

  • Arterial blood pressure
  • Intracranial pressure
  • Non-invasive blood pressure simulators
  • Simulators

ASJC Scopus subject areas

  • Mechanical Engineering
  • Medicine(all)

Cite this

A statistical model and simulator for cardiovascular pressure signals. / Staats, C.; Austin, Daniel; Aboy, M.

In: Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, Vol. 222, No. 6, 01.06.2008, p. 991-998.

Research output: Contribution to journalArticle

@article{f0bbafe49fc44992b355dda7aa0ac3f1,
title = "A statistical model and simulator for cardiovascular pressure signals",
abstract = "Physiological signal simulators are often used to conduct validation studies of commercially available devices such as oscillometric non-invasive blood pressure (NIBP) monitors. Numerous assessment studies have been conducted using simulators to validate commercial NIBP monitors. While there are several simulators commercially available to evaluate oscillometric NIBP devices, currently there are no simulators designed to validate invasive pressure signal devices. A statistical model and simulator for invasive cardiovascular pressure signals such as arterial blood pressure and intracranial pressure are described. The model incorporates the effects of respiration on pressure signals and can be used to generate synthetic signals with time and frequency domain characteristics matching any desired subject population. Additionally, the way that noise and artefacts typically present in real pressure signals should be modelled is described. The proposed statistical model is a useful tool for validation of algorithms designed to process or analyse biomedical pressure signals to estimate parameters of clinical interest such as the cardiac frequency, heart rate variability, respiratory frequency, and pulse pressure variation in the presence of noise. The model can be used to simulate signals in order to validate commercial devices that process and analyse invasive pressure signals.",
keywords = "Arterial blood pressure, Intracranial pressure, Non-invasive blood pressure simulators, Simulators",
author = "C. Staats and Daniel Austin and M. Aboy",
year = "2008",
month = "6",
day = "1",
doi = "10.1243/09544119JEIM348",
language = "English (US)",
volume = "222",
pages = "991--998",
journal = "Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine",
issn = "0954-4119",
publisher = "SAGE Publications Ltd",
number = "6",

}

TY - JOUR

T1 - A statistical model and simulator for cardiovascular pressure signals

AU - Staats, C.

AU - Austin, Daniel

AU - Aboy, M.

PY - 2008/6/1

Y1 - 2008/6/1

N2 - Physiological signal simulators are often used to conduct validation studies of commercially available devices such as oscillometric non-invasive blood pressure (NIBP) monitors. Numerous assessment studies have been conducted using simulators to validate commercial NIBP monitors. While there are several simulators commercially available to evaluate oscillometric NIBP devices, currently there are no simulators designed to validate invasive pressure signal devices. A statistical model and simulator for invasive cardiovascular pressure signals such as arterial blood pressure and intracranial pressure are described. The model incorporates the effects of respiration on pressure signals and can be used to generate synthetic signals with time and frequency domain characteristics matching any desired subject population. Additionally, the way that noise and artefacts typically present in real pressure signals should be modelled is described. The proposed statistical model is a useful tool for validation of algorithms designed to process or analyse biomedical pressure signals to estimate parameters of clinical interest such as the cardiac frequency, heart rate variability, respiratory frequency, and pulse pressure variation in the presence of noise. The model can be used to simulate signals in order to validate commercial devices that process and analyse invasive pressure signals.

AB - Physiological signal simulators are often used to conduct validation studies of commercially available devices such as oscillometric non-invasive blood pressure (NIBP) monitors. Numerous assessment studies have been conducted using simulators to validate commercial NIBP monitors. While there are several simulators commercially available to evaluate oscillometric NIBP devices, currently there are no simulators designed to validate invasive pressure signal devices. A statistical model and simulator for invasive cardiovascular pressure signals such as arterial blood pressure and intracranial pressure are described. The model incorporates the effects of respiration on pressure signals and can be used to generate synthetic signals with time and frequency domain characteristics matching any desired subject population. Additionally, the way that noise and artefacts typically present in real pressure signals should be modelled is described. The proposed statistical model is a useful tool for validation of algorithms designed to process or analyse biomedical pressure signals to estimate parameters of clinical interest such as the cardiac frequency, heart rate variability, respiratory frequency, and pulse pressure variation in the presence of noise. The model can be used to simulate signals in order to validate commercial devices that process and analyse invasive pressure signals.

KW - Arterial blood pressure

KW - Intracranial pressure

KW - Non-invasive blood pressure simulators

KW - Simulators

UR - http://www.scopus.com/inward/record.url?scp=58149142502&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58149142502&partnerID=8YFLogxK

U2 - 10.1243/09544119JEIM348

DO - 10.1243/09544119JEIM348

M3 - Article

VL - 222

SP - 991

EP - 998

JO - Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine

JF - Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine

SN - 0954-4119

IS - 6

ER -