(Chemical Equation Presented) Watching live: The FRET reporter PENN/SATE (see picture; FRET = fluorescence resonance energy transfer) is membrane permeant and enters cells and small organisms by using a prodrug approach. Once inside cells the reporter is cleaved by phospholipases, which results in a 30-fold change in the emission ratio.
- Bioorganic chemistry
- FRET (fluorescence resonance energy transfer)
- Fluorescent probes
- Signal transduction
ASJC Scopus subject areas