A single spinal lesion arising from an intradural meningioma contiguous with an extradural lymphoma: Case report

Pawel P. Jankowski, Lissa Baird, Sassan Keshavarzi, Mary E. Goolsby, William R. Taylor, Andrew D. Nguyen

Research output: Contribution to journalArticle


The authors describe here a unique case of contiguous, synchronous meningioma and lymphoma in the spinal column. Both tumors were present at the same vertebral level, one intradural and the other extradural. A patient presented with bilateral leg pain, acute weakness, and sensory loss in the lower extremities. Magnetic resonance imaging revealed an intradural mass at T6-7 with ambiguous boundaries relative to the thecal sac and compressing the spinal cord. The patient underwent resection of the epidural and intradural mass at T6-7. Histopathology revealed the epidural specimen to be a double-hit B-cell lymphoma and the intradural mass to be a transitional meningioma. Postoperatively, the patient did well, with an immediate return of strength and sensation. A postoperative MR image showed complete resection of the intradural mass. The authors suggest that biopsy may be prudent in patients with known systemic lymphoma presenting with a spinal lesion that has unclear boundaries relative to the thecal sac prior to commencing radiation and chemotherapy.

Original languageEnglish (US)
Pages (from-to)263-267
Number of pages5
JournalJournal of Neurosurgery: Spine
Issue number3
StatePublished - Sep 2012
Externally publishedYes



  • Contiguous and synchronous tumor
  • Double-hit lymphoma
  • Oncology
  • Spine
  • Transitional meningioma

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery
  • Neurology

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