A review of vascular disease risk factors and multiple sclerosis

Meena R. Kannan, Vijayshree Yadav

Research output: Contribution to journalReview articlepeer-review


Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system and the most common non-traumatic cause of disability in young adults. Recent research shows that vascular disease risk factors (VDRFs) such as obesity, smoking, hyperlipidemia, hypertension, type II diabetes mellitus, and metabolic syndrome, can influence MS on its onset, disease activity, progression, and resultant disability. This review evaluates the current knowledge on the role of VDRFs on outcomes among people with MS (PwMS) and shows that while VDRF prevalence may or may not be higher among PwMS compared with the general population, its presence can influence MS in myriad ways. Management of VDRFs through early detection and treatment may be a promising approach to improving outcomes in PwMS.

Original languageEnglish (US)
Pages (from-to)90-93
Number of pages4
JournalEuropean Neurological Review
Issue number2
StatePublished - 2017


  • Dyslipidemia
  • Hypertension
  • Metabolic syndrome
  • Multiple sclerosis
  • Obesity
  • Smoking
  • Type II diabetes

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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