A real-time 3-dimensional digital Doppler method for measurement of flow rate and volume through mitral valve in children: A validation study compared with magnetic resonance imaging

Shuping Ge, Liping Bu, Honghai Zhang, Erik Schelbert, Michelle Disterhoft, Xiangning Li, Xiaokui Li, David Sahn, Alan Stolpen, Milan Sonka

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

We developed and assessed a real-time 3-dimensional (3D) digital Doppler method for measurement of flow volumes through the mitral valve in children. A total of 13 children (aged 10.46 ± 2.5 years; 8 boys/5 girls) were enrolled. An ultrasound system (Sonos 7500, Philips, Andover, Mass) was used to acquire raw 3D velocity data for flow measurement based on Gaussian control surface theorem [flow (mL/s) = mean velocity × flow area]. Stroke volume (SV) measured by real-time 3D digital Doppler with the control surface at the mitral valve annulus or orifice was compared with the SV by phase velocity cine magnetic resonance imaging (MRI) at the ascending aorta and by left ventricular volumetric MRI measurement. The best correlation and agreement were seen at the mitral valve orifice by real-time 3D digital Doppler compared with SV by phase velocity cine MRI at the ascending aorta (r = 0.92, mean difference = -5.2 ± 12.0 mL) and SV by left ventricular volumetric MRI measurement (r = 0.94, mean difference = -0.2 ± 10.3 mL).

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalJournal of the American Society of Echocardiography
Volume18
Issue number1
DOIs
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'A real-time 3-dimensional digital Doppler method for measurement of flow rate and volume through mitral valve in children: A validation study compared with magnetic resonance imaging'. Together they form a unique fingerprint.

  • Cite this