A RAVE about opioid withdrawal

Veronica Alvarez; Seksiri Arttamangkul; John T. Williams

doi:10.1016/S0896-6273(01)00530-X

A RAVE about opioid withdrawal

Veronica Alvarez, Seksiri Arttamangkul, John T. Williams

Vollum Institute

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Abstract

Control of trafficking of g protein-linked receptors is thought to be an important regulatory mechanism for receptor signaling. Finn and Whistler test the hypothesis that agonist-induced trafficking of opioid receptors regulates the development of tolerance and dependence. The results show that measures of tolerance and withdrawal to morphine are decreased under conditions where receptors are trafficked through the endocytic/recycling pathway.

Original language	English (US)
Pages (from-to)	761-763
Number of pages	3
Journal	Neuron
Volume	32
Issue number	5
DOIs	https://doi.org/10.1016/S0896-6273(01)00530-X
State	Published - Dec 6 2001

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/S0896-6273(01)00530-X

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title = "A RAVE about opioid withdrawal",

abstract = "Control of trafficking of g protein-linked receptors is thought to be an important regulatory mechanism for receptor signaling. Finn and Whistler test the hypothesis that agonist-induced trafficking of opioid receptors regulates the development of tolerance and dependence. The results show that measures of tolerance and withdrawal to morphine are decreased under conditions where receptors are trafficked through the endocytic/recycling pathway.",

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N2 - Control of trafficking of g protein-linked receptors is thought to be an important regulatory mechanism for receptor signaling. Finn and Whistler test the hypothesis that agonist-induced trafficking of opioid receptors regulates the development of tolerance and dependence. The results show that measures of tolerance and withdrawal to morphine are decreased under conditions where receptors are trafficked through the endocytic/recycling pathway.

AB - Control of trafficking of g protein-linked receptors is thought to be an important regulatory mechanism for receptor signaling. Finn and Whistler test the hypothesis that agonist-induced trafficking of opioid receptors regulates the development of tolerance and dependence. The results show that measures of tolerance and withdrawal to morphine are decreased under conditions where receptors are trafficked through the endocytic/recycling pathway.

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DO - 10.1016/S0896-6273(01)00530-X

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A RAVE about opioid withdrawal

Abstract

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