A prospective model of care for breast cancer rehabilitation

Bone health and arthralgias

Kerri Winters-Stone, Anna L. Schwartz, Sandra C. Hayes, Carol J. Fabian, Kristin L. Campbell

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Musculoskeletal health can be compromised by breast cancer treatment. In particular, bone loss and arthralgias are prevalent side effects experienced by women treated with chemotherapy and/or adjuvant endocrine therapy. Bone loss leads to osteoporosis and related fractures, while arthralgias threaten quality of life and compliance to treatment. Because the processes that lead to these musculoskeletal problems are initiated when treatment begins, early identification of women who may be at higher risk of developing problems, routine monitoring of bone density and pain at certain stages of treatment, and prudent application of therapeutic interventions are key to preventing and/or minimizing musculoskeletal sequelae. Exercise may be a particularly suitable intervention strategy because of its potential to address a number of impairments; it may slow bone loss, appears to reduce joint pain in noncancer conditions, and improves other breast cancer outcomes. Research efforts continue in the areas of etiology, measurement, and treatment of bone loss and arthralgias. The purpose of this review is to provide an overview of the current knowledge on the management and treatment of bone loss and arthralgias in breast cancer survivors and to present a framework for rehabilitation care to preserve musculoskeletal health in women treated for breast cancer.

Original languageEnglish (US)
Pages (from-to)2288-2299
Number of pages12
JournalCancer
Volume118
Issue numberSUPPL.8
DOIs
StatePublished - Apr 15 2012

Fingerprint

Bone Neoplasms
Arthralgia
Rehabilitation
Breast Neoplasms
Health
Bone and Bones
Therapeutics
Knowledge Management
Women's Health
Adjuvant Chemotherapy
Bone Density
Osteoporosis
Survivors
Quality of Life
Exercise
Pain

Keywords

  • Fracture
  • Joint pain
  • Osteoporosis
  • Quality of life

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Winters-Stone, K., Schwartz, A. L., Hayes, S. C., Fabian, C. J., & Campbell, K. L. (2012). A prospective model of care for breast cancer rehabilitation: Bone health and arthralgias. Cancer, 118(SUPPL.8), 2288-2299. https://doi.org/10.1002/cncr.27465

A prospective model of care for breast cancer rehabilitation : Bone health and arthralgias. / Winters-Stone, Kerri; Schwartz, Anna L.; Hayes, Sandra C.; Fabian, Carol J.; Campbell, Kristin L.

In: Cancer, Vol. 118, No. SUPPL.8, 15.04.2012, p. 2288-2299.

Research output: Contribution to journalArticle

Winters-Stone, K, Schwartz, AL, Hayes, SC, Fabian, CJ & Campbell, KL 2012, 'A prospective model of care for breast cancer rehabilitation: Bone health and arthralgias', Cancer, vol. 118, no. SUPPL.8, pp. 2288-2299. https://doi.org/10.1002/cncr.27465
Winters-Stone, Kerri ; Schwartz, Anna L. ; Hayes, Sandra C. ; Fabian, Carol J. ; Campbell, Kristin L. / A prospective model of care for breast cancer rehabilitation : Bone health and arthralgias. In: Cancer. 2012 ; Vol. 118, No. SUPPL.8. pp. 2288-2299.
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