A primer on incorporating sex as a biological variable into the conduct and reporting of basic and clinical research studies

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1 Scopus citations

Abstract

The recent move to require sex as a biological variable (SABV), which includes gender, into the reporting of research published by the American Journal of Physiology-Heart and Circulatory Physiology follows a growing, and much-needed, trend by journals. Understandably, there is concern over how to do this without adding considerable work, especially if one's primary research focus is not on elucidating sex/gender differences. The purpose of this article is to provide additional guidance and examples on how to incorporate SABV into the conduct and reporting of basic and clinical research. Using examples from our research, which includes both studies focused and not focused on sex/gender differences, we offer suggestions for how to incorporate SABV into basic and clinical research studies.

Original languageEnglish (US)
Pages (from-to)H350-H354
JournalAmerican Journal of Physiology - Heart and Circulatory Physiology
Volume322
Issue number3
DOIs
StatePublished - Mar 2022

Keywords

  • Cardiovascular
  • Gender
  • Heart failure
  • Sex
  • Study design

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)

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