A pediatric case of T-cell prolymphocytic leukemia

Bryan Mitton; Steven Coutre; Jennifer Willert; Krysta Schlis; Matthew Porteus; Sandhya Kharbanda; Rajni Agarwal-Hashmi

doi:10.1002/pbc.25336

A pediatric case of T-cell prolymphocytic leukemia

Bryan Mitton, Steven Coutre, Jennifer Willert, Krysta Schlis, Matthew Porteus, Sandhya Kharbanda, Rajni Agarwal-Hashmi

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

T-cell Prolymphocytic Leukemia (T-PLL) is a rare entity, and to date has never been reported in children. Here, we describe the first pediatric case of T-PLL in a 16-year old male and review his clinical course through treatment. He underwent therapy with alemtuzumab and pentostatin, which was successful in inducing initial remission. He then underwent an allogeneic matched sibling stem cell transplant following a myeloablative conditioning regimen and remains disease-free 1.5 years after diagnosis.

Original language	English (US)
Pages (from-to)	1061-1062
Number of pages	2
Journal	Pediatric Blood and Cancer
Volume	62
Issue number	6
DOIs	https://doi.org/10.1002/pbc.25336
State	Published - Jun 1 2015
Externally published	Yes

Keywords

Bone marrow transplant
Pediatrics
T-cell prolymphocytic leukemia

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1002/pbc.25336

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title = "A pediatric case of T-cell prolymphocytic leukemia",

abstract = "T-cell Prolymphocytic Leukemia (T-PLL) is a rare entity, and to date has never been reported in children. Here, we describe the first pediatric case of T-PLL in a 16-year old male and review his clinical course through treatment. He underwent therapy with alemtuzumab and pentostatin, which was successful in inducing initial remission. He then underwent an allogeneic matched sibling stem cell transplant following a myeloablative conditioning regimen and remains disease-free 1.5 years after diagnosis.",

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AU - Mitton, Bryan

AU - Coutre, Steven

AU - Willert, Jennifer

AU - Schlis, Krysta

AU - Porteus, Matthew

AU - Kharbanda, Sandhya

AU - Agarwal-Hashmi, Rajni

PY - 2015/6/1

Y1 - 2015/6/1

N2 - T-cell Prolymphocytic Leukemia (T-PLL) is a rare entity, and to date has never been reported in children. Here, we describe the first pediatric case of T-PLL in a 16-year old male and review his clinical course through treatment. He underwent therapy with alemtuzumab and pentostatin, which was successful in inducing initial remission. He then underwent an allogeneic matched sibling stem cell transplant following a myeloablative conditioning regimen and remains disease-free 1.5 years after diagnosis.

AB - T-cell Prolymphocytic Leukemia (T-PLL) is a rare entity, and to date has never been reported in children. Here, we describe the first pediatric case of T-PLL in a 16-year old male and review his clinical course through treatment. He underwent therapy with alemtuzumab and pentostatin, which was successful in inducing initial remission. He then underwent an allogeneic matched sibling stem cell transplant following a myeloablative conditioning regimen and remains disease-free 1.5 years after diagnosis.

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KW - Pediatrics

KW - T-cell prolymphocytic leukemia

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A pediatric case of T-cell prolymphocytic leukemia

Abstract

Keywords

ASJC Scopus subject areas

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