A normal initial colonoscopy after age 50 does not predict a polyp-free status for life

S. Squillace, P. Berggreen, P. Jaffe, M (Brian) Fennerty, L. Hixson, H. Garewal, R. E. Sampliner

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Objectives: The prevalence of colon polyps increases with age in the general population. It is unknown whether a lack of adenomatous polyps determined at one time point after the age of 50 is predictive of a subsequent low risk of polyp development. Methods: Twenty-nine patients between ages 50 and 70 who had no prior history of polyps and had a normal colonoscopy at least 5 yr previously were recruited for follow-up colonoscopy to evaluate the incidence of neoplastic disease in this presumably low-risk group. Results: The incidence of adenomatous polyps after a mean of 5.74 yr was 41.4% (95% confidence interval: 23.5-61.1%). A total of 20 adenomatous polyps were found in 12 patients. Seven polyps were 5 mm or more in size. Conclusions: We conclude that in patients with no history of colonic neoplasia who are 50 yr old, or older, the finding of a normal colonoscopy does not predict diminished risk of neoplasia.

Original languageEnglish (US)
Pages (from-to)1156-1159
Number of pages4
JournalAmerican Journal of Gastroenterology
Volume89
Issue number8
StatePublished - 1994
Externally publishedYes

Fingerprint

Colonoscopy
Polyps
Adenomatous Polyps
Incidence
Neoplasms
Colon
Confidence Intervals
Population

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Squillace, S., Berggreen, P., Jaffe, P., Fennerty, M. B., Hixson, L., Garewal, H., & Sampliner, R. E. (1994). A normal initial colonoscopy after age 50 does not predict a polyp-free status for life. American Journal of Gastroenterology, 89(8), 1156-1159.

A normal initial colonoscopy after age 50 does not predict a polyp-free status for life. / Squillace, S.; Berggreen, P.; Jaffe, P.; Fennerty, M (Brian); Hixson, L.; Garewal, H.; Sampliner, R. E.

In: American Journal of Gastroenterology, Vol. 89, No. 8, 1994, p. 1156-1159.

Research output: Contribution to journalArticle

Squillace, S, Berggreen, P, Jaffe, P, Fennerty, MB, Hixson, L, Garewal, H & Sampliner, RE 1994, 'A normal initial colonoscopy after age 50 does not predict a polyp-free status for life', American Journal of Gastroenterology, vol. 89, no. 8, pp. 1156-1159.
Squillace, S. ; Berggreen, P. ; Jaffe, P. ; Fennerty, M (Brian) ; Hixson, L. ; Garewal, H. ; Sampliner, R. E. / A normal initial colonoscopy after age 50 does not predict a polyp-free status for life. In: American Journal of Gastroenterology. 1994 ; Vol. 89, No. 8. pp. 1156-1159.
@article{29bd9a2f785d4a9fb868a409b9102f3f,
title = "A normal initial colonoscopy after age 50 does not predict a polyp-free status for life",
abstract = "Objectives: The prevalence of colon polyps increases with age in the general population. It is unknown whether a lack of adenomatous polyps determined at one time point after the age of 50 is predictive of a subsequent low risk of polyp development. Methods: Twenty-nine patients between ages 50 and 70 who had no prior history of polyps and had a normal colonoscopy at least 5 yr previously were recruited for follow-up colonoscopy to evaluate the incidence of neoplastic disease in this presumably low-risk group. Results: The incidence of adenomatous polyps after a mean of 5.74 yr was 41.4{\%} (95{\%} confidence interval: 23.5-61.1{\%}). A total of 20 adenomatous polyps were found in 12 patients. Seven polyps were 5 mm or more in size. Conclusions: We conclude that in patients with no history of colonic neoplasia who are 50 yr old, or older, the finding of a normal colonoscopy does not predict diminished risk of neoplasia.",
author = "S. Squillace and P. Berggreen and P. Jaffe and Fennerty, {M (Brian)} and L. Hixson and H. Garewal and Sampliner, {R. E.}",
year = "1994",
language = "English (US)",
volume = "89",
pages = "1156--1159",
journal = "American Journal of Gastroenterology",
issn = "0002-9270",
publisher = "Nature Publishing Group",
number = "8",

}

TY - JOUR

T1 - A normal initial colonoscopy after age 50 does not predict a polyp-free status for life

AU - Squillace, S.

AU - Berggreen, P.

AU - Jaffe, P.

AU - Fennerty, M (Brian)

AU - Hixson, L.

AU - Garewal, H.

AU - Sampliner, R. E.

PY - 1994

Y1 - 1994

N2 - Objectives: The prevalence of colon polyps increases with age in the general population. It is unknown whether a lack of adenomatous polyps determined at one time point after the age of 50 is predictive of a subsequent low risk of polyp development. Methods: Twenty-nine patients between ages 50 and 70 who had no prior history of polyps and had a normal colonoscopy at least 5 yr previously were recruited for follow-up colonoscopy to evaluate the incidence of neoplastic disease in this presumably low-risk group. Results: The incidence of adenomatous polyps after a mean of 5.74 yr was 41.4% (95% confidence interval: 23.5-61.1%). A total of 20 adenomatous polyps were found in 12 patients. Seven polyps were 5 mm or more in size. Conclusions: We conclude that in patients with no history of colonic neoplasia who are 50 yr old, or older, the finding of a normal colonoscopy does not predict diminished risk of neoplasia.

AB - Objectives: The prevalence of colon polyps increases with age in the general population. It is unknown whether a lack of adenomatous polyps determined at one time point after the age of 50 is predictive of a subsequent low risk of polyp development. Methods: Twenty-nine patients between ages 50 and 70 who had no prior history of polyps and had a normal colonoscopy at least 5 yr previously were recruited for follow-up colonoscopy to evaluate the incidence of neoplastic disease in this presumably low-risk group. Results: The incidence of adenomatous polyps after a mean of 5.74 yr was 41.4% (95% confidence interval: 23.5-61.1%). A total of 20 adenomatous polyps were found in 12 patients. Seven polyps were 5 mm or more in size. Conclusions: We conclude that in patients with no history of colonic neoplasia who are 50 yr old, or older, the finding of a normal colonoscopy does not predict diminished risk of neoplasia.

UR - http://www.scopus.com/inward/record.url?scp=0028023361&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028023361&partnerID=8YFLogxK

M3 - Article

C2 - 8053427

AN - SCOPUS:0028023361

VL - 89

SP - 1156

EP - 1159

JO - American Journal of Gastroenterology

JF - American Journal of Gastroenterology

SN - 0002-9270

IS - 8

ER -