A new optional vena cava filter: Retrieval at 12 weeks in an animal model

Elias N. Brountzos, John A. Kaufman, Anthony C. Venbrux, P. Rand Brown, Jason Harry, Thomas F. Kinst, Stephen Kleshinski, Adrian C. Ravenscroft

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

PURPOSE: To test the feasibility and safety of percutaneous retrieval of a new inferior vena cava (IVC) filter, the Recovery Filter (RF), acutely and after 12-week implantation in sheep. MATERIALS AND METHODS: The RF is a bilevel filter with stabilizing arms and elastic hooks that allow retrieval with a unique retrieval cone after incorporation into the wall of the IVC. Twenty-four filters were placed in the infrarenal IVCs of 18 sheep. In six sheep, two filters were placed and then removed immediately; three sheep were killed acutely and three were killed after a healing period of 3 weeks. In 12 sheep, a single filter was placed and then removed 12 weeks later; six were killed after retrieval and six were killed after an 8-week healing period. RESULTS: The mean (±SD) transverse vena caval diameter was 15.3 mm ± 2. All filters were deployed as intended and retrieved without difficulty. At sacrifice, there was no evidence of IVC perforation or retroperitoneal abnormality. The IVCs of the animals in the acute retrieval group showed minimal acute superficial injury that was largely reversed at 3 weeks. At 12 weeks, there was evidence of transmural incorporation of filter elements with narrowing of the IVCs. Solitary fibrotic abnormalities were present in the aorta adjacent to IVC lesions in nine of the 12 animals in the 12-week group. The IVC and aortic abnormalities were largely healed, with reversal of IVC narrowing after 8 weeks. CONCLUSION: The recovery filter can be reliably and safely retrieved acutely and 12 weeks after implantation in sheep.

Original languageEnglish (US)
Pages (from-to)763-772
Number of pages10
JournalJournal of Vascular and Interventional Radiology
Volume14
Issue number6
DOIs
StatePublished - Jun 1 2003

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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    Brountzos, E. N., Kaufman, J. A., Venbrux, A. C., Brown, P. R., Harry, J., Kinst, T. F., Kleshinski, S., & Ravenscroft, A. C. (2003). A new optional vena cava filter: Retrieval at 12 weeks in an animal model. Journal of Vascular and Interventional Radiology, 14(6), 763-772. https://doi.org/10.1097/01.RVI.0000079986.80153.CC