A new DNA polymerase activity of Escherichia coli. I. Purification and properties of the activity present in E. coli polAl

Robb E. Moses, Charles C. Richardson

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A new DNA polymerase activity present in cells of Escherichia coli has been purified to homogeneity from E. coli polAl. The new enzyme (polymerase II) differs from the previously described polymerase (polymerase I) in chromatographic properties, sensitivity to sulfhydryl-blocking agents, response to antibody, and template requirements.

Original languageEnglish (US)
Pages (from-to)1557-1564
Number of pages8
JournalBiochemical and Biophysical Research Communications
Issue number6
StatePublished - Dec 24 1970


ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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