A Longitudinal Study of LASIK Flap and Stromal Thickness with High-speed Optical Coherence Tomography

Yan Li, Marcelo V. Netto, Raj Shekhar, Ronald R. Krueger, David Huang

Research output: Contribution to journalArticle

80 Citations (Scopus)

Abstract

Objective: To assess corneal anatomic changes after LASIK with a high-speed corneal and anterior segment optical coherence tomography (CAS-OCT) system. Design: Cross-sectional observational study. Participants: Fifty-one eyes of 26 healthy persons undergoing LASIK. Methods: The CAS-OCT prototype operated at a 1.3-μm wavelength and 2000 axial scans/second. The corneas were scanned with a flap profile pattern (horizontal line, 512 axial scans) and a flap map pattern (4 radials, 256 axial scans each). Both patterns are 8 mm long and are centered on the corneal vertex. LASIK flaps were created using either a mechanical microkeratome (Hansatome; Bausch & Lomb, Inc., Rochester, NY) or a femtosecond laser (Pulsion; IntraLase Corp., Irvine, CA). Intraoperative pachymetry was performed using a 50-MHz ultrasound probe. Three OCT scans were obtained on preoperative and post-LASIK visits up to 6 months. An automated algorithm was developed to process the OCT images and to calculate corneal, flap, and stromal bed thickness profiles and maps. The profiles and maps were divided into central (diameter,

Original languageEnglish (US)
JournalOphthalmology
Volume114
Issue number6
DOIs
StatePublished - Jun 2007

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Laser In Situ Keratomileusis
Optical Coherence Tomography
Longitudinal Studies
Cornea
Observational Studies
Lasers
Cross-Sectional Studies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

A Longitudinal Study of LASIK Flap and Stromal Thickness with High-speed Optical Coherence Tomography. / Li, Yan; Netto, Marcelo V.; Shekhar, Raj; Krueger, Ronald R.; Huang, David.

In: Ophthalmology, Vol. 114, No. 6, 06.2007.

Research output: Contribution to journalArticle

Li, Yan ; Netto, Marcelo V. ; Shekhar, Raj ; Krueger, Ronald R. ; Huang, David. / A Longitudinal Study of LASIK Flap and Stromal Thickness with High-speed Optical Coherence Tomography. In: Ophthalmology. 2007 ; Vol. 114, No. 6.
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