A long sought after "receptor" for ERFE?

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations


In this issue of Blood, Arezes and colleagues present new and exciting evidence that erythropoietin (EPO) suppresses bone morphogenetic protein (BMP)-mediated signaling in an erythroferrone (ERFE)-dependent mechanism and ERFE in turn interferes with the binding of a specific set of BMPs to their receptors.1 These findings represent a breakthrough in the understanding of how EPO and ERFE function to decrease hepcidin expression.

Original languageEnglish (US)
Pages (from-to)1463-1464
Number of pages2
Issue number14
StatePublished - Oct 4 2018

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology


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