A long sought after "receptor" for ERFE?

Research output: Contribution to journalReview article

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Abstract

In this issue of Blood, Arezes and colleagues present new and exciting evidence that erythropoietin (EPO) suppresses bone morphogenetic protein (BMP)-mediated signaling in an erythroferrone (ERFE)-dependent mechanism and ERFE in turn interferes with the binding of a specific set of BMPs to their receptors.1 These findings represent a breakthrough in the understanding of how EPO and ERFE function to decrease hepcidin expression.

Original languageEnglish (US)
Pages (from-to)1463-1464
Number of pages2
JournalBlood
Volume132
Issue number14
DOIs
Publication statusPublished - Oct 4 2018

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ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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