A long sought after "receptor" for ERFE?

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

In this issue of Blood, Arezes and colleagues present new and exciting evidence that erythropoietin (EPO) suppresses bone morphogenetic protein (BMP)-mediated signaling in an erythroferrone (ERFE)-dependent mechanism and ERFE in turn interferes with the binding of a specific set of BMPs to their receptors.1 These findings represent a breakthrough in the understanding of how EPO and ERFE function to decrease hepcidin expression.

Original languageEnglish (US)
Pages (from-to)1463-1464
Number of pages2
JournalBlood
Volume132
Issue number14
DOIs
StatePublished - Oct 4 2018

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Erythropoietin
Hepcidins
Bone Morphogenetic Proteins
Blood

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

Cite this

A long sought after "receptor" for ERFE? / Zhang, An-Sheng; Enns, Caroline.

In: Blood, Vol. 132, No. 14, 04.10.2018, p. 1463-1464.

Research output: Contribution to journalReview article

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abstract = "In this issue of Blood, Arezes and colleagues present new and exciting evidence that erythropoietin (EPO) suppresses bone morphogenetic protein (BMP)-mediated signaling in an erythroferrone (ERFE)-dependent mechanism and ERFE in turn interferes with the binding of a specific set of BMPs to their receptors.1 These findings represent a breakthrough in the understanding of how EPO and ERFE function to decrease hepcidin expression.",
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