A Histone Deacetylase Regulates Addiction

Research output: Contribution to journalShort survey

10 Scopus citations

Abstract

Epigenetic modification of chromatin has been proposed to translate environmental stimuli into persistent "cellular memories." Recent studies suggest that epigenetic pathways regulate long-term behavioral adaptation in the nervous system. In this issue of Neuron, Renthal et al. utilize genetic manipulations of HDAC5 to provide strong evidence for a role for histone acetylation in the behavioral response to cocaine.

Original languageEnglish (US)
Pages (from-to)415-417
Number of pages3
JournalNeuron
Volume56
Issue number3
DOIs
StatePublished - Nov 8 2007

ASJC Scopus subject areas

  • Neuroscience(all)

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