A fungal story fatal forty DDI: Fluconazole, phenytoin, CYP2C9, CYP2C19

Jerusha Taylor; Ansgar Brambrink

doi:10.1007/978-1-4614-7495-1_107

A fungal story fatal forty DDI: Fluconazole, phenytoin, CYP2C9, CYP2C19

Jerusha Taylor, Ansgar Brambrink

Anesthesiology & Perioperative Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This cases discusses a pharamcokinetic interaction between phenytoin and fl uconazole, resulting in phenytoin toxicity. Phenytoin is a cytochrome P450 2C9 and 2C19 substrate and fl uconazole is a 2C9 and 2C19 inhibitor.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	491-493
Number of pages	3
ISBN (Print)	9781461474951, 9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_107
State	Published - Sep 15 2015

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-1-4614-7495-1_107

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abstract = "This cases discusses a pharamcokinetic interaction between phenytoin and fl uconazole, resulting in phenytoin toxicity. Phenytoin is a cytochrome P450 2C9 and 2C19 substrate and fl uconazole is a 2C9 and 2C19 inhibitor.",

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