A fungal story fatal forty DDI: Fluconazole, phenytoin, CYP2C9, CYP2C19

Jerusha Taylor, Ansgar Brambrink

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This cases discusses a pharamcokinetic interaction between phenytoin and fl uconazole, resulting in phenytoin toxicity. Phenytoin is a cytochrome P450 2C9 and 2C19 substrate and fl uconazole is a 2C9 and 2C19 inhibitor.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Pages491-493
Number of pages3
ISBN (Print)9781461474951, 9781461474944
DOIs
StatePublished - Sep 15 2015

ASJC Scopus subject areas

  • Medicine(all)

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    Taylor, J., & Brambrink, A. (2015). A fungal story fatal forty DDI: Fluconazole, phenytoin, CYP2C9, CYP2C19. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 491-493). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_107