A concise algorithm for detection of vibration from Fourier domain OCT

Steven Jacques, S. Ramamoorthy, T. C. Petrie, Anh Nguyen-Huynh, Alfred Nuttall

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Optical interferometry using Fourier domain OCT (FD-OCT) can image structures using vibration as the contrast mechanism. An A-scan measurement of light reflected from a tissue at a position x,y yields an intensity spectrum, I(λ), which is sequentially acquired over a short time period, 88 ms, to yield 1000 spectra at equally spaced time points, I(λ,t), while an audio frequency of sound pressure is imparted to the tissue to induce vibration. Analysis converts I(λ,t) into displacement Δz(z,t) of tissue structures along the z axis. Fourier analysis converts Δz(t) at each z into a vibration spectrum, and the amplitude of vibration at the driving audio frequency is specified. This process is repeated for each x position at a given y, to yield an image of vibration amplitude, A(z,x) [nm]. Hence, vibration amplitude becomes the contrast mechanism. This method is not a new idea, but a derivative of Doppler OCT. This report simply provides a concise algorithm in MATLAB for students wishing to implement vibration measurements using FD-OCT. An example shows the vibration of the ossicles of the middle ear viewed through the intact tympanic membrane.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8565
DOIs
Publication statusPublished - 2013
EventPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
Duration: Feb 2 2013Feb 7 2013

Other

OtherPhotonic Therapeutics and Diagnostics IX
CountryUnited States
CitySan Francisco, CA
Period2/2/132/7/13

    Fingerprint

Keywords

  • Ear
  • OCT
  • Optical Coherence Tomography
  • Ossicles
  • Vibration

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Jacques, S., Ramamoorthy, S., Petrie, T. C., Nguyen-Huynh, A., & Nuttall, A. (2013). A concise algorithm for detection of vibration from Fourier domain OCT. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8565). [85652B] https://doi.org/10.1117/12.2008966