A concise algorithm for detection of vibration from Fourier domain OCT

S. L. Jacques, S. Ramamoorthy, T. C. Petrie, A. Nguyen-Huynh, A. L. Nuttall

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Optical interferometry using Fourier domain OCT (FD-OCT) can image structures using vibration as the contrast mechanism. An A-scan measurement of light reflected from a tissue at a position x,y yields an intensity spectrum, I(λ), which is sequentially acquired over a short time period, 88 ms, to yield 1000 spectra at equally spaced time points, I(λ,t), while an audio frequency of sound pressure is imparted to the tissue to induce vibration. Analysis converts I(λ,t) into displacement Δz(z,t) of tissue structures along the z axis. Fourier analysis converts Δz(t) at each z into a vibration spectrum, and the amplitude of vibration at the driving audio frequency is specified. This process is repeated for each x position at a given y, to yield an image of vibration amplitude, A(z,x) [nm]. Hence, vibration amplitude becomes the contrast mechanism. This method is not a new idea, but a derivative of Doppler OCT. This report simply provides a concise algorithm in MATLAB for students wishing to implement vibration measurements using FD-OCT. An example shows the vibration of the ossicles of the middle ear viewed through the intact tympanic membrane.

Original languageEnglish (US)
Title of host publicationPhotonic Therapeutics and Diagnostics IX
DOIs
StatePublished - May 30 2013
EventPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
Duration: Feb 2 2013Feb 7 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8565
ISSN (Print)1605-7422

Other

OtherPhotonic Therapeutics and Diagnostics IX
CountryUnited States
CitySan Francisco, CA
Period2/2/132/7/13

Keywords

  • Ear
  • OCT
  • Optical Coherence Tomography
  • Ossicles
  • Vibration

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Jacques, S. L., Ramamoorthy, S., Petrie, T. C., Nguyen-Huynh, A., & Nuttall, A. L. (2013). A concise algorithm for detection of vibration from Fourier domain OCT. In Photonic Therapeutics and Diagnostics IX [85652B] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8565). https://doi.org/10.1117/12.2008966