Abstract
The ability to identify medical reversals and other low-value medical practices is an essential prerequisite for efforts to reduce spending on such practices. Through an analysis of more than 3000 randomized controlled trials (RCTs) published in three leading medical journals (the Journal of the American Medical Association, the Lancet, and the New England Journal of Medicine), we have identified 396 medical reversals. Most of the studies (92%) were conducted on populations in high-income counties, cardiovascular disease was the most common medical category (20%), and medication was the most common type of intervention (33%).
| Original language | English (US) |
|---|---|
| Journal | eLife |
| Volume | 8 |
| DOIs | |
| State | Published - Jun 11 2019 |
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Keywords
- evidence-based medicine
- human
- low-value care
- medical reversal
ASJC Scopus subject areas
- Neuroscience(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Immunology and Microbiology(all)
Cite this
A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals. / Herrera-Perez, Diana; Haslam, Alyson; Crain, Tyler; Gill, Jennifer; Livingston, Catherine; Kaestner, Victoria; Hayes, Michael; Morgan, Dan; Cifu, Adam S.; Prasad, Vinay.
In: eLife, Vol. 8, 11.06.2019.Research output: Contribution to journal › Article
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TY - JOUR
T1 - A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals
AU - Herrera-Perez, Diana
AU - Haslam, Alyson
AU - Crain, Tyler
AU - Gill, Jennifer
AU - Livingston, Catherine
AU - Kaestner, Victoria
AU - Hayes, Michael
AU - Morgan, Dan
AU - Cifu, Adam S.
AU - Prasad, Vinay
PY - 2019/6/11
Y1 - 2019/6/11
N2 - The ability to identify medical reversals and other low-value medical practices is an essential prerequisite for efforts to reduce spending on such practices. Through an analysis of more than 3000 randomized controlled trials (RCTs) published in three leading medical journals (the Journal of the American Medical Association, the Lancet, and the New England Journal of Medicine), we have identified 396 medical reversals. Most of the studies (92%) were conducted on populations in high-income counties, cardiovascular disease was the most common medical category (20%), and medication was the most common type of intervention (33%).
AB - The ability to identify medical reversals and other low-value medical practices is an essential prerequisite for efforts to reduce spending on such practices. Through an analysis of more than 3000 randomized controlled trials (RCTs) published in three leading medical journals (the Journal of the American Medical Association, the Lancet, and the New England Journal of Medicine), we have identified 396 medical reversals. Most of the studies (92%) were conducted on populations in high-income counties, cardiovascular disease was the most common medical category (20%), and medication was the most common type of intervention (33%).
KW - evidence-based medicine
KW - human
KW - low-value care
KW - medical reversal
UR - http://www.scopus.com/inward/record.url?scp=85067789782&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85067789782&partnerID=8YFLogxK
U2 - 10.7554/eLife.45183
DO - 10.7554/eLife.45183
M3 - Article
C2 - 31182188
AN - SCOPUS:85067789782
VL - 8
JO - eLife
JF - eLife
SN - 2050-084X
ER -