A comprehensive analysis of single-trial and criterion maze learning in three inbred strains of mice

John Jr Crabbe, Herbert P. Alpern

Research output: Contribution to journalArticle

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Abstract

A six-unit, appetitively motivated, brightness discrimination maze for mice was employed to examine the learning of males and females of three inbred strains of mice (A/J, C57BL/6J, DBA/2J). Error measures indexed memory for the maze habit, while latency measures also indexed performance factors unrelated to memory. Strain differences with respect to latency measures, but not error measures, were found. These results were interpreted to indicate an essential similarity in the memory capabilities of these strains for the task employed. It was concluded that this task would be appropriate for studies of memory functioning in mice that desire to manipulate both physiological and genetic variables.

Original languageEnglish (US)
Pages (from-to)681-693
Number of pages13
JournalBehavioral Biology
Volume9
Issue number6
DOIs
Publication statusPublished - 1973
Externally publishedYes

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ASJC Scopus subject areas

  • Physiology
  • Medicine(all)

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