TY - JOUR
T1 - A comprehensive analysis of single-trial and criterion maze learning in three inbred strains of mice
AU - Crabbe, John C.
AU - Alpern, Herbert P.
N1 - Funding Information:
1This investigation was supported by National Institute of Mental Health Grant MH 11167 and MH 20574-01.
PY - 1973/12
Y1 - 1973/12
N2 - A six-unit, appetitively motivated, brightness discrimination maze for mice was employed to examine the learning of males and females of three inbred strains of mice (A/J, C57BL/6J, DBA/2J). Error measures indexed memory for the maze habit, while latency measures also indexed performance factors unrelated to memory. Strain differences with respect to latency measures, but not error measures, were found. These results were interpreted to indicate an essential similarity in the memory capabilities of these strains for the task employed. It was concluded that this task would be appropriate for studies of memory functioning in mice that desire to manipulate both physiological and genetic variables.
AB - A six-unit, appetitively motivated, brightness discrimination maze for mice was employed to examine the learning of males and females of three inbred strains of mice (A/J, C57BL/6J, DBA/2J). Error measures indexed memory for the maze habit, while latency measures also indexed performance factors unrelated to memory. Strain differences with respect to latency measures, but not error measures, were found. These results were interpreted to indicate an essential similarity in the memory capabilities of these strains for the task employed. It was concluded that this task would be appropriate for studies of memory functioning in mice that desire to manipulate both physiological and genetic variables.
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U2 - 10.1016/S0091-6773(73)80129-4
DO - 10.1016/S0091-6773(73)80129-4
M3 - Article
C2 - 4764252
AN - SCOPUS:0015740274
VL - 9
SP - 681
EP - 693
JO - Communications in behavioral biology. Part A: [Original articles]
JF - Communications in behavioral biology. Part A: [Original articles]
SN - 1074-7427
IS - 6
ER -