Abstract
The effects of stress on plasma renin activity (PRA), plasma prolactin and corticosterone levels, and hypothalamic 5-HT and 5-HIAA concentrations were investigated using a 3 and 12 min conditioned fear (CER) paradigm; 20 min immobilization; 20 min exposure to shallow or deep cold water; 2, 12 and 22 min of intermittent footshock with or without 20 min recovery; and, a 3 min CER with 0, 10, 30 and 60 min recovery. PRA was increased by all the stressors, except shallow cold water, reaching a maximun after 12 min and returning to control values within 10-20 min post-stress. Prolactin levels also were increased by all the stressors, except shallow and deep cold water. Prolactin levels were maximal after 12 min and returned to baseline within 20-60 min post-stress, depending on the stressor. Corticosterone levels were elevated by all the stressors, but not as rapidly as PRA or prolactin, reaching a maximum after about 20 min and returning to baseline concentrations within 30-60 min post-stress. None of the stressors produced significant changes in hypothalamic 5-HT and 5-HIAA concentrations.
Original language | English (US) |
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Pages (from-to) | 33-43 |
Number of pages | 11 |
Journal | Physiology and Behavior |
Volume | 39 |
Issue number | 1 |
DOIs | |
State | Published - 1987 |
Keywords
- 5-Hydroxyindoleacetic acid (5-HIAA)
- Cold swim
- Conditioned fear
- Corticosterone
- Hypothalamus
- Immobilization
- Prolactin
- Rat
- Renin
- Serotonin (5-HT)
- Stress
ASJC Scopus subject areas
- Experimental and Cognitive Psychology
- Behavioral Neuroscience