A clinical trial of CCNU (1‐(2 chloroethyl)‐3‐cyclohexyl‐1‐nitrosourea) (NSC 79037) in advanced ovarian carcinoma

Truman M. Sasaki; Donald B. McConnell; H. Stephens Moseley; G. Craig Merhoff; William S. Fletcher

doi:10.1002/jso.2930070504

A clinical trial of CCNU (1‐(2 chloroethyl)‐3‐cyclohexyl‐1‐nitrosourea) (NSC 79037) in advanced ovarian carcinoma

Truman M. Sasaki, Donald B. McConnell, H. Stephens Moseley, G. Craig Merhoff, William S. Fletcher

Surgery

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

CCNU is a useful drug in treating advanced ovarian carcinoma. Of patients with advanced ovarian carcinoma 37% responded favorably to CCNU. Thrombocytopenia was the primary toxic reaction. Clinical trials are in progress to compare the relative effectiveness, the degree of cross‐resistance, and the difference in toxicity between CCNU and alkylating agents.

Original language	English (US)
Pages (from-to)	347-350
Number of pages	4
Journal	Journal of surgical oncology
Volume	7
Issue number	5
DOIs	https://doi.org/10.1002/jso.2930070504
State	Published - 1975

Keywords

CCNU
ovarian carcinoma

ASJC Scopus subject areas

Surgery
Oncology

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10.1002/jso.2930070504

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abstract = "CCNU is a useful drug in treating advanced ovarian carcinoma. Of patients with advanced ovarian carcinoma 37% responded favorably to CCNU. Thrombocytopenia was the primary toxic reaction. Clinical trials are in progress to compare the relative effectiveness, the degree of cross‐resistance, and the difference in toxicity between CCNU and alkylating agents.",

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AU - McConnell, Donald B.

AU - Moseley, H. Stephens

AU - Merhoff, G. Craig

AU - Fletcher, William S.

PY - 1975

Y1 - 1975

N2 - CCNU is a useful drug in treating advanced ovarian carcinoma. Of patients with advanced ovarian carcinoma 37% responded favorably to CCNU. Thrombocytopenia was the primary toxic reaction. Clinical trials are in progress to compare the relative effectiveness, the degree of cross‐resistance, and the difference in toxicity between CCNU and alkylating agents.

AB - CCNU is a useful drug in treating advanced ovarian carcinoma. Of patients with advanced ovarian carcinoma 37% responded favorably to CCNU. Thrombocytopenia was the primary toxic reaction. Clinical trials are in progress to compare the relative effectiveness, the degree of cross‐resistance, and the difference in toxicity between CCNU and alkylating agents.

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KW - ovarian carcinoma

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A clinical trial of CCNU (1‐(2 chloroethyl)‐3‐cyclohexyl‐1‐nitrosourea) (NSC 79037) in advanced ovarian carcinoma

Abstract

Keywords

ASJC Scopus subject areas

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