A central role of salicylic acid in plant disease resistance

Terrence P. Delaney, Scott Uknes, Bernard Vernooij, Leslie Friedrich, Kristianna Weymann, David Negrotto, Thomas Gaffney, Manuela Gut-Rella, Helmut Kessmann, Eric Ward, John Ryals

Research output: Contribution to journalArticle

1214 Citations (Scopus)

Abstract

Transgenic tobacco and Arabidopsis thaliana expressing the bacterial enzyme salicylate hydroxylase cannot accumulate salicylic acid (SA). This defect not only makes the plants unable to induce systemic acquired resistance, but also leads to increased susceptibility to viral, fungal, and bacterial pathogens. The enhanced susceptibility extends even to host-pathogen combinations that would normally result in genetic resistance. Therefore, SA accumulation is essential for expression of multiple modes of plant disease resistance.

Original languageEnglish (US)
Pages (from-to)1247-1250
Number of pages4
JournalScience
Volume266
Issue number5188
StatePublished - 1994
Externally publishedYes

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Plant Diseases
Disease Resistance
Salicylic Acid
salicylate 1-monooxygenase
Arabidopsis
Tobacco
Enzymes

ASJC Scopus subject areas

  • Medicine(all)
  • General

Cite this

Delaney, T. P., Uknes, S., Vernooij, B., Friedrich, L., Weymann, K., Negrotto, D., ... Ryals, J. (1994). A central role of salicylic acid in plant disease resistance. Science, 266(5188), 1247-1250.

A central role of salicylic acid in plant disease resistance. / Delaney, Terrence P.; Uknes, Scott; Vernooij, Bernard; Friedrich, Leslie; Weymann, Kristianna; Negrotto, David; Gaffney, Thomas; Gut-Rella, Manuela; Kessmann, Helmut; Ward, Eric; Ryals, John.

In: Science, Vol. 266, No. 5188, 1994, p. 1247-1250.

Research output: Contribution to journalArticle

Delaney, TP, Uknes, S, Vernooij, B, Friedrich, L, Weymann, K, Negrotto, D, Gaffney, T, Gut-Rella, M, Kessmann, H, Ward, E & Ryals, J 1994, 'A central role of salicylic acid in plant disease resistance', Science, vol. 266, no. 5188, pp. 1247-1250.
Delaney TP, Uknes S, Vernooij B, Friedrich L, Weymann K, Negrotto D et al. A central role of salicylic acid in plant disease resistance. Science. 1994;266(5188):1247-1250.
Delaney, Terrence P. ; Uknes, Scott ; Vernooij, Bernard ; Friedrich, Leslie ; Weymann, Kristianna ; Negrotto, David ; Gaffney, Thomas ; Gut-Rella, Manuela ; Kessmann, Helmut ; Ward, Eric ; Ryals, John. / A central role of salicylic acid in plant disease resistance. In: Science. 1994 ; Vol. 266, No. 5188. pp. 1247-1250.
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