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  • Jeffrey Kaye

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific Reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Advancing Research on Care Needs and Supportive Approaches for Persons With Dementia: Recommendations and Rationale

Kolanowski, A., Fortinsky, R. H., Calkins, M., Devanand, D. P., Gould, E., Heller, T., Hodgson, N. A., Kales, H. C., Kaye, J., Lyketsos, C., Resnick, B., Schicker, M. & Zimmerman, S., Dec 2018, In : Journal of the American Medical Directors Association. 19, 12, p. 1047-1053 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

A Multi-study Coordinated Meta-analysis of Pulmonary Function and Cognition in Aging

Duggan, E. C., Piccinin, A. M., Clouston, S., Koval, A. V., Robitaille, A., Zammit, A. R., Wu, C., Brown, C. L., Lee, L. O., Finkel, D., Beasley, W. H., Kaye, J., Terrera, G. M., Katz, M., Lipton, R. B., Deeg, D., Bennett, D. A., Praetorius Björk, M., Johansson, B., Spiro, A. & 2 others, Weuve, J. & Hofer, S. M., Oct 4 2019, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 74, 11, p. 1793-1804 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

An Agenda for Addressing Multimorbidity and Racial and Ethnic Disparities in Alzheimer's Disease and Related Dementia

Quiñones, A. R., Kaye, J., Allore, H. G., Botoseneanu, A. & Thielke, S. M., Jan 1 2020, In : American Journal of Alzheimer's Disease and Other Dementias. 35, p. 1533317520960874

Research output: Contribution to journalArticle

Open Access

An ecologically valid, longitudinal, and unbiased assessment of treatment efficacy in alzheimer disease (The Evaluate-ad Trial): Proof-of-concept study

Thomas, N. W. D., Beattie, Z., Marcoe, J., Wright, K., Sharma, N., Mattek, N., Dodge, H., Wild, K. & Kaye, J., May 2020, In : JMIR Research Protocols. 9, 5, e17603.

Research output: Contribution to journalArticle

Open Access

APOE DNA methylation is altered in Lewy body dementia

Tulloch, J., Leong, L., Chen, S., Keene, C. D., Millard, S. P., Shutes-David, A., Lopez, O. L., Kofler, J., Kaye, J. A., Woltjer, R., Nelson, P. T., Neltner, J. H., Jicha, G. A., Galasko, D., Masliah, E., Leverenz, J. B., Yu, C. E. & Tsuang, D., Jul 2018, In : Alzheimer's and Dementia. 14, 7, p. 889-894 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

A randomized clinical trial to evaluate home-based assessment of people over 75 years old

Alzheimer Disease Cooperative Study Investigators, May 2019, In : Alzheimer's and Dementia. 15, 5, p. 615-624 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Association of perivascular localization of aquaporin-4 with cognition and Alzheimer disease in aging brains

Zeppenfeld, D. M., Simon, M., Haswell, J. D., D'Abreo, D., Murchison, C., Quinn, J., Grafe, M., Woltjer, R. R., Kaye, J. & Iliff, J., Jan 1 2017, In : JAMA Neurology. 74, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle

92 Scopus citations

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : JAMA Neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

215 Scopus citations

Baseline NAWM structural integrity and CBF predict periventricular WMH expansion over time

Promjunyakul, N. O., Dodge, H. H., Lahna, D., Boespflug, E. L., Kaye, J. A., Rooney, W. D. & Silbert, L. C., Jun 12 2018, In : Neurology. 90, 24, p. e2107-e2118

Research output: Contribution to journalArticle

11 Scopus citations

Biometric monitoring devices for assessing end points in clinical trials: Developing an ecosystem

Arneric, S. P., Cedarbaum, J. M., Khozin, S., Papapetropoulos, S., Hill, D. L., Ropacki, M., Rhodes, J., Dacks, P. A., Hudson, L. D., Gordon, M. F., Kern, V. D., Romero, K., Vradenburg, G., Au, R., Karlin, D. R., Facheris, M. F., Fitzer-Attas, C. J., Vitolo, O. V., Wang, J., Miller, B. M. & 1 others, Kaye, J. A., Oct 1 2017, In : Nature Reviews Drug Discovery. 16, 10, 1 p.

Research output: Contribution to journalLetter

17 Scopus citations

Brain health INnovation Diplomacy: A model binding diverse disciplines to manage the promise and perils of technological innovation

Ternes, K., Iyengar, V., Lavretsky, H., Dawson, W. D., Booi, L., Ibanez, A., Vahia, I., Reynolds, C., Dekosky, S., Cummings, J., Miller, B., Perissinotto, C., Kaye, J. & Eyre, H. A., Aug 1 2020, In : International Psychogeriatrics. 32, 8, p. 955-979 25 p.

Research output: Contribution to journalReview article

3 Scopus citations

Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states

Mahjoub, I., Mahjoub, M. A., Rekik, I., Weiner, M., Aisen, P., Petersen, R., Jack, C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R. & 221 others, Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Grifth, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graf-Radford, N., Parftt, F., Kendall, T., Johnson, H., Farlow, M., Hake, A. M., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Johnson, P. L., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Dec 1 2018, In : Scientific Reports. 8, 1, 4103.

Research output: Contribution to journalArticle

26 Scopus citations

Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features

Singanamalli, A., Wang, H., Madabhushi, A., Weiner, M., Aisen, P., Petersen, R., Jack, C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R. & 221 others, Dolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff-Radford, N., Parfitt, F., Kendall, T., Johnson, H., Farlow, M., Marie Hake, A., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Lynn Johnson, P., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Robbartha, Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific Reports. 7, 1, 8137.

Research output: Contribution to journalArticle

3 Scopus citations

Categorizing Sleep in Older Adults with Wireless Activity Monitors Using LSTM Neural Networks

Yildiz, S., Opel, R. A., Elliott, J. E., Kaye, J., Cao, H. & Lim, M. M., Jul 2019, 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Institute of Electrical and Electronics Engineers Inc., p. 3368-3372 5 p. 8857453. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer’s disease

For the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In : Scientific Reports. 8, 1, 13807.

Research output: Contribution to journalArticle

4 Scopus citations
Open Access
13 Scopus citations
3 Scopus citations

Dementia Care Comes Home: Patient and Caregiver Assessment via Telemedicine

Lindauer, A., Seelye, A., Lyons, B., Dodge, H. H., Mattek, N., Mincks, K., Kaye, J. & Erten-Lyons, D., Oct 1 2017, In : Gerontologist. 57, 5, p. e85-e93

Research output: Contribution to journalArticle

20 Scopus citations

Detecting cognitive changes in preclinical Alzheimer's disease: A review of its feasibility

Mortamais, M., Ash, J. A., Harrison, J., Kaye, J., Kramer, J., Randolph, C., Pose, C., Albala, B., Ropacki, M., Ritchie, C. W. & Ritchie, K., Apr 1 2017, In : Alzheimer's and Dementia. 13, 4, p. 468-492 25 p.

Research output: Contribution to journalReview article

45 Scopus citations

Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease: A Randomized Clinical Trial

Van Dyck, C. H., Nygaard, H. B., Chen, K., Donohue, M. C., Raman, R., Rissman, R. A., Brewer, J. B., Koeppe, R. A., Chow, T. W., Rafii, M. S., Gessert, D., Choi, J., Turner, R. S., Kaye, J. A., Gale, S. A., Reiman, E. M., Aisen, P. S. & Strittmatter, S. M., Oct 2019, In : JAMA Neurology. 76, 10, p. 1219-1229 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
2 Scopus citations

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, Jan 1 2018, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journalArticle

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Alzheimer Disease Genetics Consortium (ADGC), The European Alzheimer’s Disease Initiative (EADI), Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), & Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES), Mar 1 2019, In : Nature genetics. 51, 3, p. 414-430 17 p.

Research output: Contribution to journalArticle

220 Scopus citations
Open Access

Increased free prostate specific antigen serum levels in Alzheimer's disease, correlation with Cognitive Decline

Sternberg, Z., Podolsky, R., Nir, A., Yu, J., Nir, R., Halvorsen, S. W., Chadha, K., Quinn, J., Kaye, J. & Kolb, C., May 15 2019, In : Journal of the neurological sciences. 400, p. 188-193 6 p.

Research output: Contribution to journalArticle

Internet searches and their relationship to cognitive function in older adults: Cross-sectional analysis

Austin, J., Hollingshead, K. & Kaye, J., Sep 2017, In : Journal of medical Internet research. 19, 9, e307.

Research output: Contribution to journalArticle

7 Scopus citations

Investigating the concept of participant burden in aging technology research

Kabacińska, K., Sharma, N., Kaye, J., Mattek, N., Kuzeljevic, B. & Robillard, J. M., Feb 12 2020, In : BMC Geriatrics. 20, 1, 50.

Research output: Contribution to journalArticle

Open Access

Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

Huang, M., Yang, W., Feng, Q., Chen, W., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., Shaw, L. M., Kaye, J., Quinn, J., Silbert, L., Lind, B. & 219 others, Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., DeToledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Maillard, P., Olichney, J., DeCarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Jan 12 2017, In : Scientific Reports. 7, 39880.

Research output: Contribution to journalArticle

27 Scopus citations

Methodology for establishing a community-wide life laboratory for capturing unobtrusive and continuous remote activity and health data

Kaye, J., Reynolds, C., Bowman, M., Sharma, N., Riley, T., Golonka, O., Lee, J., Quinn, C., Beattie, Z., Austin, J., Seelye, A., Wild, K. & Mattek, N., Jul 27 2018, In : Journal of Visualized Experiments. 2018, 137, e56942.

Research output: Contribution to journalArticle

9 Scopus citations

MR imaging-based multimodal autoidentification of perivascular spaces (mMAPS): Automated morphologic segmentation of enlarged perivascular spaces at clinical field strength

Boespflug, E. L., Schwartz, D. L., Lahna, D., Pollock, J., Iliff, J. J., Kaye, J. A., Rooney, W. & Silbert, L. C., Feb 2018, In : RADIOLOGY. 286, 2, p. 632-642 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer’s Disease using structural MR and FDG-PET images

Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2018, In : Scientific Reports. 8, 1, 5697.

Research output: Contribution to journalArticle

Open Access
56 Scopus citations

Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis

Irwin, D. J., Grossman, M., Weintraub, D., Hurtig, H. I., Duda, J. E., Xie, S. X., Lee, E. B., Van Deerlin, V. M., Lopez, O. L., Kofler, J. K., Nelson, P. T., Jicha, G. A., Woltjer, R., Quinn, J. F., Kaye, J., Leverenz, J. B., Tsuang, D., Longfellow, K., Yearout, D., Kukull, W. & 4 others, Keene, C. D., Montine, T. J., Zabetian, C. P. & Trojanowski, J. Q., Jan 1 2017, In : The Lancet Neurology. 16, 1, p. 55 1 p.

Research output: Contribution to journalArticle

153 Scopus citations

Observation of Reduced Homeostatic Metabolic Activity and/or Coupling in White Matter Aging

Anderson, V. C., Tagge, I. J., Li, X., Quinn, J. F., Kaye, J. A., Bourdette, D. N., Spain, R. I., Riccelli, L. P., Sammi, M. K., Springer, C. S. & Rooney, W. D., Sep 1 2020, In : Journal of Neuroimaging. 30, 5, p. 658-665 8 p.

Research output: Contribution to journalArticle

Participant satisfaction with dementia prevention research: Results from Home-Based Assessment trial

Sano, M., Egelko, S., Zhu, C. W., Li, C., Donohue, M. C., Ferris, S., Kaye, J., Mundt, J. C., Sun, C. K., Aisen, P. S. & Feldman, H. H., Nov 1 2018, In : Alzheimer's & dementia : the journal of the Alzheimer's Association. 14, 11, p. 1397-1405 9 p.

Research output: Contribution to journalArticle

Passive assessment of routine driving with unobtrusive sensors: A new approach for identifying and monitoring functional level in normal aging and mild cognitive impairment

Seelye, A., Mattek, N., Sharma, N., Witter, P., Brenner, A., Wild, K., Dodge, H. & Kaye, J., 2017, In : Journal of Alzheimer's Disease. 59, 4, p. 1427-1437 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pathologies underlying longitudinal cognitive decline in the oldest old

Nguyen, M. T., Mattek, N., Woltjer, R., Howieson, D., Silbert, L., Hofer, S., Kaye, J., Dodge, H. & Erten-Lyons, D., 2018, In : Alzheimer Disease and Associated Disorders. 32, 4, p. 265-269 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J., Shaw, L. M. & 293 others, Khachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In : Scientific Reports. 7, 1, 14052.

Research output: Contribution to journalArticle

4 Scopus citations

Performance-based and observational assessments in clinical trials across the alzheimer’s disease spectrum

Harvey, P. D., Cosentino, S., Curiel, R., Goldberg, T. E., Kaye, J., Loewenstein, D., Marson, D., Salmon, D., Wesnes, K. & Posner, H., 2017, In : Innovations in Clinical Neuroscience. 14, 1-2, p. 30-39 10 p.

Research output: Contribution to journalReview article

10 Scopus citations

Predicting Alzheimer’s disease progression using multi-modal deep learning approach

for Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific Reports. 9, 1, 1952.

Research output: Contribution to journalArticle

Open Access
32 Scopus citations
34 Scopus citations

Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

For the Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific Reports. 9, 1, 2235.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations
Open Access
5 Scopus citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R. & 426 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, W. T., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. 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A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In : Nature genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

259 Scopus citations

Recommended cognitive outcomes in preclinical Alzheimer's disease: Consensus statement from the European Prevention of Alzheimer's Dementia project

Ritchie, K., Ropacki, M., Albala, B., Harrison, J., Kaye, J., Kramer, J., Randolph, C. & Ritchie, C. W., Feb 1 2017, In : Alzheimer's and Dementia. 13, 2, p. 186-195 10 p.

Research output: Contribution to journalShort survey

41 Scopus citations

Regional Amyloid-β Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer’s Dementia

For the Alzheimer’s Disease Neuroimaging Initiative, Jul 1 2019, In : Molecular Neurobiology. 56, 7, p. 4916-4924 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Retention of Alzheimer Disease Research Participants

Grill, J. D., Kwon, J., Teylan, M. A., Pierce, A., Vidoni, E. D., Burns, J. M., Lindauer, A., Quinn, J., Kaye, J., Gillen, D. L. & Nan, B., 2019, In : Alzheimer Disease and Associated Disorders. 33, 4, p. 299-306 8 p.

Research output: Contribution to journalArticle

Risk of incident clinical diagnosis of Alzheimer's disease–type dementia attributable to pathology-confirmed vascular disease

and the & SMART data consortium, Jun 2017, In : Alzheimer's and Dementia. 13, 6, p. 613-623 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Serum hepcidin levels, iron dyshomeostasis and cognitive loss in Alzheimer'S Disease

Sternberg, Z., Hu, Z., Sternberg, D., Waseh, S., Quinn, J. F., Wild, K., Kaye, J., Zhao, L. & Garrick, M., 2017, In : Aging and Disease. 8, 2, p. 215-227 13 p.

Research output: Contribution to journalArticle

14 Scopus citations