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  • Gordon Mills
2020

AACR calls on congress to take immediate action against COVID-19 and protect patients with cancer during the pandemic

Mardis, E. R., Ribas, A., Hait, W. N., Jaffee, E. M., Foti, M., Abate-Shen, C., Albini, A., Bernards, R., Cruz-Correa, M. R., Flaherty, K. T., Greenberg, P. D., June, C. H., Knudsen, K. E., Liu, E. T., Mills, G. B., Piccart, M. J., Roussel, M. F., Siu, L. L., Swanton, C. & Tuveson, D. A., Jun 2020, In : Cancer discovery. 10, 6, p. 771-774 4 p.

Research output: Contribution to journalArticle

Open Access

Candidate biomarker assessment for pharmacological response

Reinhold, W. C., Elloumi, F., Varma, S., Robert, J., Mills, G. B. & Pommier, Y., Oct 2020, In : Translational Oncology. 13, 10, 100830.

Research output: Contribution to journalArticle

Open Access

Clinical relevance of TP53 hotspot mutations in high-grade serous ovarian cancers

Tuna, M., Ju, Z., Yoshihara, K., Amos, C. I., Tanyi, J. L. & Mills, G. B., Feb 4 2020, In : British Journal of Cancer. 122, 3, p. 405-412 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Comparison of Real-Time Fluorescence Confocal Digital Microscopy With Hematoxylin-Eosin-Stained Sections of Core-Needle Biopsy Specimens

Krishnamurthy, S., Sabir, S., Ban, K., Wu, Y., Sheth, R., Tam, A., Meric-Bernstam, F., Shaw, K., Mills, G., Bassett, R., Hamilton, S., Hicks, M. & Gupta, S., Mar 2 2020, In : JAMA Network Open. 3, 3, p. e200476

Research output: Contribution to journalArticle

Open Access

Comprehensive assessment of computational algorithms in predicting cancer driver mutations

Chen, H., Li, J., Wang, Y., Ng, P. K. S., Tsang, Y. H., Shaw, K. R., Mills, G. B. & Liang, H., Feb 20 2020, In : Genome biology. 21, 1, 43.

Research output: Contribution to journalArticle

Open Access

Development of prediction models for lymph node metastasis in endometrioid endometrial carcinoma

Berg, H. F., Ju, Z., Myrvold, M., Fasmer, K. E., Halle, M. K., Hoivik, E. A., Westin, S. N., Trovik, J., Haldorsen, I. S., Mills, G. B., Krakstad, C. & Werner, H. M. J., Jan 1 2020, (Accepted/In press) In : British Journal of Cancer.

Research output: Contribution to journalArticle

Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression

Tsang, Y. H., Wang, Y., Kong, K., Grzeskowiak, C., Zagorodna, O., Dogruluk, T., Lu, H., Villafane, N., Bhavana, V. H., Moreno, D., Elsea, S. H., Liang, H., Mills, G. B. & Scott, K. L., Apr 2020, In : eLife. 9, e48963.

Research output: Contribution to journalArticle

Open Access

Downregulation of the ubiquitin-e3 ligase rnf123 promotes upregulation of the nf-κb1 target serpine1 in aggressive glioblastoma tumors

Wang, X., Bustos, M. A., Zhang, X., Ramos, R. I., Tan, C., Iida, Y., Chang, S. C., Salomon, M. P., Tran, K., Gentry, R., Kravtsova-Ivantsiv, Y., Kelly, D. F., Mills, G. B., Ciechanover, A., Mao, Y. & Hoon, D. S. B., May 2020, In : Cancers. 12, 5, 1081.

Research output: Contribution to journalArticle

Open Access

MAPK pathway mutations in head and neck cancer affect immune microenvironments and ErbB3 signaling

Ngan, H. L., Liu, Y., Fong, A. Y., Poon, P. H. Y., Yeung, C. K., Chan, S. S. M., Lau, A., Piao, W., Li, H., Tse, J. S. W., Lo, K. W., Chan, S. M., Su, Y. X., Chan, J. Y. K., Lau, C. W., Mills, G. B., Grandis, J. R. & Lui, V. W. Y., May 7 2020, In : Life science alliance. 3, 4, LSA.201900545.

Research output: Contribution to journalArticle

Open Access

Mutant P53 induces MELK expression by release of wild-type P53-dependent suppression of FOXM1

Bollu, L. R., Shepherd, J., Zhao, D., Ma, Y., Tahaney, W., Speers, C., Mazumdar, A., Mills, G. B. & Brown, P. H., Dec 1 2020, In : npj Breast Cancer. 6, 1, 2.

Research output: Contribution to journalArticle

Open Access

Phase II, 2-stage, 2-arm, PIK3CA mutation stratified trial of MK-2206 in recurrent endometrial cancer

Myers, A. P., Konstantinopoulos, P. A., Barry, W. T., Luo, W., Broaddus, R. R., Makker, V., Drapkin, R., Liu, J., Doyle, A., Horowitz, N. S., Meric-Bernstam, F., Birrer, M., Aghajanian, C., Coleman, R. L., Mills, G. B., Cantley, L. C., Matulonis, U. A. & Westin, S. N., Jul 15 2020, In : International Journal of Cancer. 147, 2, p. 413-422 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis

Yu, K., Lin, C. C. J., Hatcher, A., Lozzi, B., Kong, K., Huang-Hobbs, E., Cheng, Y. T., Beechar, V. B., Zhu, W., Zhang, Y., Chen, F., Mills, G. B., Mohila, C. A., Creighton, C. J., Noebels, J. L., Scott, K. L. & Deneen, B., Feb 6 2020, In : Nature. 578, 7793, p. 166-171 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer

McGrail, D. J., Garnett, J., Yin, J., Dai, H., Shih, D. J. H., Lam, T. N. A., Li, Y., Sun, C., Li, Y., Schmandt, R., Wu, J. Y., Hu, L., Liang, Y., Peng, G., Jonasch, E., Menter, D., Yates, M. S., Kopetz, S., Lu, K. H., Broaddus, R. & 3 others, Mills, G. B., Sahni, N. & Lin, S. Y., Mar 16 2020, In : Cancer Cell. 37, 3, p. 371-386.e12

Research output: Contribution to journalArticle

2 Scopus citations

Results of an abbreviated phase II study of AKT inhibitor MK-2206 in the treatment of recurrent platinum-resistant high grade serous ovarian, fallopian tube, or primary peritoneal carcinoma (NCT 01283035)

Lee, E. K., Tan-Wasielewski, Z., Aghajanian, C., Coleman, R. L., Curtis, J., Hirsch, M. S., Matulonis, U. A., Cantley, L. C., Mills, G. B., Doyle, L. A. & Liu, J. F., May 2020, In : Gynecologic Oncology Reports. 32, 100546.

Research output: Contribution to journalArticle

Open Access

Sex-associated molecular differences for cancer immunotherapy

Ye, Y., Jing, Y., Li, L., Mills, G. B., Diao, L., Liu, H. & Han, L., Dec 1 2020, In : Nature communications. 11, 1, 1779.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Upregulation of cell surface GD3 ganglioside phenotype is associated with human melanoma brain metastasis

Ramos, R. I., Bustos, M. A., Wu, J., Jones, P., Chang, S. C., Kiyohara, E., Tran, K., Zhang, X., Stern, S. L., Izraely, S., Sagi-Assif, O., Witz, I. P., Davies, M. A., Mills, G. B., Kelly, D. F., Irie, R. F. & Hoon, D. S. B., 2020, (Accepted/In press) In : Molecular Oncology.

Research output: Contribution to journalArticle

Open Access

Which path to follow? Utilizing proteomics to improve therapy choices for breast cancer patients

Blucher, A. S., Mills, G. B. & Tsang, Y. H., Mar 3 2020, In : Expert Review of Proteomics. 17, 3, p. 187-190 4 p.

Research output: Contribution to journalEditorial

Open Access
2019

A-to-I-edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis

Xu, X., Wang, Y., Mojumdar, K., Zhou, Z., Jeong, K. J., Mangala, L. S., Yu, S., Tsang, Y. H., Rodriguez-Aguayo, C., Lu, Y., Lopez-Berestein, G., Sood, A. K., Mills, G. B. & Liang, H., Dec 2 2019, In : Journal of Clinical Investigation. 129, 12, p. 5343-5356 14 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Author Correction: Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis (Nature Communications, (2018), 9, 1, (5426), 10.1038/s41467-018-07126-9)

Liu, S., Zhang, G., Guo, J., Chen, X., Lei, J., Ze, K., Dong, L., Dai, X., Gao, Y., Song, D., Ecker, B. L., Yang, R., Feltcher, C., Peng, K., Feng, C., Chen, H., Lee, R. X., Kerestes, H., Niu, J., Kumar, S. & 15 others, Xu, W., Zhang, J., Wei, Z., Martin, J. S., Liu, X., Mills, G., Lu, Y., Guo, W., Sun, L., Zhang, L., Weeraratna, A., Herlyn, M., Wei, W., Lee, F. S. & Xu, X., Dec 1 2019, In : Nature communications. 10, 1, 1211.

Research output: Contribution to journalComment/debate

Open Access

Breast cancer quantitative proteome and proteogenomic landscape

Consortia Oslo Breast Cancer Research Consortium (OSBREAC), Dec 1 2019, In : Nature communications. 10, 1, 1600.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Characterization of hypoxia-associated molecular features to aid hypoxia-targeted therapy

Ye, Y., Hu, Q., Chen, H., Liang, K., Yuan, Y., Xiang, Y., Ruan, H., Zhang, Z., Song, A., Zhang, H., Liu, L., Diao, L., Lou, Y., Zhou, B., Wang, L., Zhou, S., Gao, J., Jonasch, E., Lin, S. H., Xia, Y. & 5 others, Lin, C., Yang, L., Mills, G. B., Liang, H. & Han, L., Apr 1 2019, In : Nature Metabolism. 1, 4, p. 431-444 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Combined MEK and Bcl-2/XL inhibition is effective in high-grade serous ovarian cancer patient–derived xenograft models and BIM levels are predictive of responsiveness

Iavarone, C., Zervantonakis, I. K., Selfors, L. M., Palakurthi, S., Liu, J. F., Drapkin, R., Matulonis, U. A., Hallberg, D., Velculescu, V. E., Leverson, J. D., Sampath, D., Mills, G. B. & Brugge, J. S., Mar 2019, In : Molecular cancer therapeutics. 18, 3, p. 642-655 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Confocal fluorescence microscopy platform suitable for rapid evaluation of small fragments of tissue in surgical pathology practice

Krishnamurthy, S., Ban, K., Shaw, K., Mills, G., Sheth, R., Tam, A., Gupta, S. & Sabir, S., Mar 1 2019, In : Archives of Pathology and Laboratory Medicine. 143, 3, p. 305-313 9 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Cooperative effect of oncogenic MET and PIK3CA in an HGF-dominant environment in breast cancer

Liu, S., Li, S., Wang, B., Liu, W., Gagea, M., Chen, H., Sohn, J., Parinyanitikul, N., Primeau, T., Do, K. A., Vande Woude, G. F., Mendelsohn, J., Ueno, N. T., Mills, G. B., Tripathy, D. & Gonzalez-Angulo, A. M., Feb 2019, In : Molecular cancer therapeutics. 18, 2, p. 399-412 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Correction: A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory (Oncotarget (2017) 8 (41806-41814) DOI: 10.18632/oncotarget.16018

Arango, N. P., Brusco, L., Shaw, K. R. M., Chen, K., Eterovic, A. K., Holla, V., Johnson, A., Litzenburger, B., Khotskaya, Y. B., Sanchez, N., Bailey, A., Zheng, X., Horombe, C., Kopetz, S., Farhangfar, C. J., Routbort, M., Broaddus, R., Bernstam, E. V., Mendelsohn, J., Mills, G. B. & 1 others, Meric-Bernstam, F., 2019, In : Oncotarget. 10, 50, 1 p.

Research output: Contribution to journalComment/debate

Open Access

Correction: Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer (Oncogene, (2017), 36, 12, (1745-1752), 10.1038/onc.2016.327)

Kang, M. H., Jeong, K. J., Kim, W. Y., Lee, H. J., Gong, G., Suh, N., Győrffy, B., Kim, S., Jeong, S. Y., Mills, G. B. & Park, Y. Y., May 30 2019, In : Oncogene. 38, 22, p. 4427-4428 2 p.

Research output: Contribution to journalComment/debate

Open Access
1 Scopus citations

Correction: RCP induces Slug expression and cancer cell invasion by stabilizing β1 integrin (Oncogene, (2017), 36, 8, (1102-1111), 10.1038/onc.2016.277)

Hwang, M. H., Cho, K. H., Jeong, K. J., Park, Y. Y., Kim, J. M., Yu, S. L., Park, C. G., Mills, G. & Lee, H. Y., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference

Bast, R. C., Matulonis, U. A., Sood, A. K., Ahmed, A. A., Amobi, A. E., Balkwill, F. R., Wielgos-Bonvallet, M., Bowtell, D. D. L., Brenton, J. D., Brugge, J. S., Coleman, R. L., Draetta, G. F., Doberstein, K., Drapkin, R. I., Eckert, M. A., Edwards, R. P., Elias, K. M., Ennis, D., Futreal, A., Gershenson, D. M. & 23 others, Greenberg, R. A., Huntsman, D. G., Ji, J. X. Y., Kohn, E. C., Iavarone, C., Lengyel, E. R., Levine, D. A., Lord, C. J., Lu, Z., Mills, G. B., Modugno, F., Nelson, B. H., Odunsi, K., Pilsworth, J. A., Rottapel, R. K., Powell, D. J., Shen, L., Shih, I. M., Spriggs, D. R., Walton, J., Zhang, K., Zhang, R. & Zou, L., Jun 15 2019, In : Cancer. 125, 12, p. 1963-1972 10 p.

Research output: Contribution to journalComment/debate

7 Scopus citations

Deregulated Gab2 phosphorylation mediates aberrant AKT and STAT3 signaling upon PIK3R1 loss in ovarian cancer

Li, X., Mak, V. C. Y., Zhou, Y., Wang, C., Wong, E. S. Y., Sharma, R., Lu, Y., Cheung, A. N. Y., Mills, G. B. & Cheung, L. W. T., Dec 1 2019, In : Nature communications. 10, 1, 716.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Detection of breast cancer stem cell gene mutations in circulating free DNA during the evolution of metastases

Liu, Z. B., Ezzedine, N. E., Eterovic, A. K., Ensor, J. E., Huang, H. J., Albanell, J., Choi, D. S., Lluch, A., Liu, Y., Rojo, F., Wong, H., Martínez-Dueñas, E., Guerrero-Zotano, Á., Shao, Z. M., Darcourt, J. G., Mills, G. B., Dave, B. & Chang, J. C., Nov 1 2019, In : Breast Cancer Research and Treatment. 178, 2, p. 251-261 11 p.

Research output: Contribution to journalArticle

Dynamic clonal remodelling in breast cancer metastases is associated with subtype conversion

Lluch, A., González-Angulo, A. M., Casadevall, D., Eterovic, A. K., Martínez de Dueñas, E., Zheng, X., Guerrero-Zotano, Á., Liu, S., Pérez, R., Chen, K., Chacón, J. I., Mills, G. B., Antolín, S., Blancas, I., López-Serra, P., Carrasco, E., Caballero, R., Prat, A., Rojo, F., Gonzalez-Perez, A. & 2 others, Meric-Bernstam, F. & Albanell, J., Oct 2019, In : European Journal of Cancer. 120, p. 54-64 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Erratum to: PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas (Nature, (2017), 10.1038/nature24040)

Lu, H., Liu, S., Zhang, G., Wu, B., Zhu, Y., Frederick, D. T., Hu, Y., Zhong, W., Randell, S., Sadek, N., Zhang, W., Chen, G., Cheng, C., Zeng, J., Wu, L. W., Zhang, J., Liu, X., Xu, W., Krepler, C., Sproesser, K. & 21 others, Xiao, M., Miao, B., Liu, J., Song, C. D., Liu, J. Y., Karakousis, G. C., Schuchter, L. M., Lu, Y., Mills, G., Cong, Y., Chernoff, J., Guo, J., Boland, G. M., Sullivan, R. J., Wei, Z., Field, J., Amaravadi, R. K., Flaherty, K. T., Herlyn, M., Xu, X. & Guo, W., Jan 10 2019, In : Nature. 565, 7738, p. E4

Research output: Contribution to journalComment/debate

Expanded analysis of secondary germline findings from matched tumor/normal sequencing identifies additional clinically significant mutations

Dumbrava, E. I., Brusco, L., Daniels, M. S., Wathoo, C., Shaw, K. R., Lu, K. H., Zheng, X., Strong, L. C., Litton, J., Arun, B. K., Eterovic, A. K., Routbort, M. J., Patel, K. P., Qi, Y., Piha-Paul, S. A., Subbiah, V., Hong, D. S., Rodon, J., Kopetz, S., Mendelsohn, J. & 3 others, Mills, G. B., Chen, K. & Meric-Bernstam, F., Jan 1 2019, In : JCO Precision Oncology. 3

Research output: Contribution to journalArticle

2 Scopus citations
8 Scopus citations

Genome-Wide Profiling of Acquired Uniparental Disomy Reveals Prognostic Factors in Head and Neck Squamous Cell Carcinoma

Tuna, M., Liu, W., Amos, C. I. & Mills, G. B., Nov 2019, In : Neoplasia (United States). 21, 11, p. 1102-1109 8 p.

Research output: Contribution to journalArticle

Open Access

GPNMB augments Wnt-1 mediated breast tumor initiation and growth by enhancing PI3K/AKT/mTOR pathway signaling and β-catenin activity

Maric, G., Annis, M. G., MacDonald, P. A., Russo, C., Perkins, D., Siwak, D. R., Mills, G. & Siegel, P. M., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

4 Scopus citations

Identification and validation of a prognostic proteomic signature for cervical cancer

Rader, J. S., Pan, A., Corbin, B., Iden, M., Lu, Y., Vellano, C. P., Akbani, R., Mills, G. & Simpson, P., Jan 1 2019, (Accepted/In press) In : Gynecologic oncology.

Research output: Contribution to journalArticle

1 Scopus citations

Impact of cold ischemic time and freeze-thaw cycles on RNA, DNA and protein quality in colorectal cancer tissues biobanking

Fan, X. J., Huang, Y., Wu, P. H., Yin, X. K., Yu, X. H., Fu, X. H., Feng, L. L., Wang, Y. L., Yi, H. J., Chen, Z. T., Yin, J. X., Zhang, D. L., Feng, W. X., Bai, S. M., Kim, T., Mills, G. B., Lu, Y. L., Wan, X. B. & Wang, L., 2019, In : Journal of Cancer. 10, 20, p. 4978-4988 11 p.

Research output: Contribution to journalArticle

Open Access

Integrated transcriptomic–genomic tool Texomer profiles cancer tissues

Wang, F., Zhang, S., Kim, T. B., Lin, Y. Y., Iqbal, R., Wang, Z., Mohanty, V., Sircar, K., Karam, J. A., Wendl, M. C., Meric-Bernstam, F., Weinstein, J. N., Ding, L., Mills, G. B. & Chen, K., May 1 2019, In : Nature Methods. 16, 5, p. 401-404 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

MERIT: Systematic Analysis and Characterization of Mutational Effect on RNA Interactome Topology

Li, Y., McGrail, D. J., Xu, J., Li, J., Liu, N. N., Sun, M., Lin, R., Pancsa, R., Zhang, J., Lee, J. S., Wang, H., Mills, G. B., Li, X., Yi, S. & Sahni, N., 2019, In : Hepatology. 70, 2, p. 532-546 15 p.

Research output: Contribution to journalArticle

7 Scopus citations

miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer

Parashar, D., Geethadevi, A., Aure, M. R., Mishra, J., George, J., Chen, C., Mishra, M. K., Tahiri, A., Zhao, W., Nair, B., Lu, Y., Mangala, L. S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Camara, A. K. S., Liang, M., Rader, J. S., Ramchandran, R., You, M., Sood, A. K. & 4 others, Kristensen, V. N., Mills, G. B., Pradeep, S. & Chaluvally-Raghavan, P., Dec 24 2019, In : Cell Reports. 29, 13, p. 4389-4406.e10

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Molecular mechanisms and pathobiology of oncogenic fusion transcripts in epithelial tumors

Tuna, M., Amos, C. I. & Mills, G. B., 2019, In : Oncotarget. 10, 21, p. 2095-2111 17 p.

Research output: Contribution to journalReview article

Open Access

Next-generation characterization of the Cancer Cell Line Encyclopedia

Ghandi, M., Huang, F. W., Jané-Valbuena, J., Kryukov, G. V., Lo, C. C., McDonald, E. R., Barretina, J., Gelfand, E. T., Bielski, C. M., Li, H., Hu, K., Andreev-Drakhlin, A. Y., Kim, J., Hess, J. M., Haas, B. J., Aguet, F., Weir, B. A., Rothberg, M. V., Paolella, B. R., Lawrence, M. S. & 48 others, Akbani, R., Lu, Y., Tiv, H. L., Gokhale, P. C., de Weck, A., Mansour, A. A., Oh, C., Shih, J., Hadi, K., Rosen, Y., Bistline, J., Venkatesan, K., Reddy, A., Sonkin, D., Liu, M., Lehar, J., Korn, J. M., Porter, D. A., Jones, M. D., Golji, J., Caponigro, G., Taylor, J. E., Dunning, C. M., Creech, A. L., Warren, A. C., McFarland, J. M., Zamanighomi, M., Kauffmann, A., Stransky, N., Imielinski, M., Maruvka, Y. E., Cherniack, A. D., Tsherniak, A., Vazquez, F., Jaffe, J. D., Lane, A. A., Weinstock, D. M., Johannessen, C. M., Morrissey, M. P., Stegmeier, F., Schlegel, R., Hahn, W. C., Getz, G., Mills, G. B., Boehm, J. S., Golub, T. R., Garraway, L. A. & Sellers, W. R., May 23 2019, In : Nature. 569, 7757, p. 503-508 6 p.

Research output: Contribution to journalArticle

127 Scopus citations

Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models

Wang, Z., Sun, K., Xiao, Y., Feng, B., Mikule, K., Ma, X. Y., Feng, N., Vellano, C. P., Federico, L., Marszalek, J. R., Mills, G., Hanke, J., Ramaswamy, S. & Wang, J., Dec 1 2019, In : Scientific Reports. 9, 1, 1853.

Research output: Contribution to journalArticle

Open Access
26 Scopus citations

Olaparib and α-specific PI3K inhibitor alpelisib for patients with epithelial ovarian cancer: a dose-escalation and dose-expansion phase 1b trial

Konstantinopoulos, P. A., Barry, W. T., Birrer, M., Westin, S. N., Cadoo, K. A., Shapiro, G. I., Mayer, E. L., O'Cearbhaill, R. E., Coleman, R. L., Kochupurakkal, B., Whalen, C., Curtis, J., Farooq, S., Luo, W., Eismann, J., Buss, M. K., Aghajanian, C., Mills, G. B., Palakurthi, S., Kirschmeier, P. & 8 others, Liu, J., Cantley, L. C., Kaufmann, S. H., Swisher, E. M., D'Andrea, A. D., Winer, E., Wulf, G. M. & Matulonis, U. A., Apr 2019, In : The Lancet Oncology. 20, 4, p. 570-580 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

PARPI triggers the STING-dependent immune response and enhances the therapeutic efficacy of immune checkpoint blockade independent of BRCANEss

Shen, J., Zhao, W., Ju, Z., Wang, L., Peng, Y., Labrie, M., Yap, T. A., Mills, G. & Peng, G., Jan 15 2019, In : Cancer Research. 79, 2, p. 311-319 9 p.

Research output: Contribution to journalArticle

56 Scopus citations

PIK3CA amplification associates with aggressive phenotype but not markers of AKT-mTOR signaling in endometrial carcinoma

Holst, F., Werner, H. M. J., Mjøs, S., Hoivik, E. A., Kusonmano, K., Wik, E., Berg, A., Birkeland, E., Gibson, W. J., Halle, M. K., Trovik, J., Cherniack, A. D., Kalland, K. H., Mills, G., Singer, C. F., Krakstad, C., Beroukhim, R. & Salvesen, H. B., Jan 1 2019, In : Clinical Cancer Research. 25, 1, p. 334-345 12 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prospective clinical sequencing of adult glioma

Zheng, S., Alfaro-Munoz, K., Wei, W., Wang, X., Wang, F., Eterovic, A. K., Shaw, K. R. M., Meric-Bernstam, F., Fuller, G. N., Chen, K., Verhaak, R. G., Mills, G. B., Yung, W. K. A., Weathers, S. P. & De Groot, J. F., Jan 1 2019, In : Molecular cancer therapeutics. 18, 5, p. 991-1000 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Protein Kinase C Quality Control by Phosphatase PHLPP1 Unveils Loss-of-Function Mechanism in Cancer

Baffi, T. R., Van, A. A. N., Zhao, W., Mills, G. B. & Newton, A. C., Apr 18 2019, In : Molecular Cell. 74, 2, p. 378-392.e5

Research output: Contribution to journalArticle

2 Scopus citations

Proteomics advances for precision therapy in ovarian cancer

Labrie, M., Kendsersky, N. D., Ma, H., Campbell, L., Eng, J., Chin, K. & Mills, G. B., Oct 3 2019, In : Expert Review of Proteomics. 16, 10, p. 841-850 10 p.

Research output: Contribution to journalReview article