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  • Kevin Winthrop
2020

American College of Rheumatology Guidance for the Management of Rheumatic Disease in Adult Patients During the COVID-19 Pandemic: Version 1

Mikuls, T. R., Johnson, S. R., Fraenkel, L., Arasaratnam, R. J., Baden, L. R., Bermas, B. L., Chatham, W., Cohen, S., Costenbader, K., Gravallese, E. M., Kalil, A. C., Weinblatt, M. E., Winthrop, K., Mudano, A. S., Turner, A. & Saag, K. G., Aug 1 2020, In : Arthritis and Rheumatology. 72, 8, p. 1241-1251 11 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

An Integrated Analysis of the Safety of Tofacitinib in Psoriatic Arthritis across Phase III and Long-Term Extension Studies with Comparison to Real-World Observational Data

Burmester, G. R., Curtis, J. R., Yun, H., FitzGerald, O., Winthrop, K. L., Azevedo, V. F., Rigby, W. F. C., Kanik, K. S., Wang, C., Biswas, P., Jones, T., Palmetto, N., Hendrikx, T., Menon, S. & Rojo, R., Apr 1 2020, In : Drug Safety. 43, 4, p. 379-392 14 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Effect of short-term methotrexate discontinuation on rheumatoid arthritis disease activity: post-hoc analysis of two randomized trials

Park, J. K., Kim, M. J., Choi, Y., Winthrop, K., Song, Y. W. & Lee, E. B., Feb 1 2020, In : Clinical Rheumatology. 39, 2, p. 375-379 5 p.

Research output: Contribution to journalArticle

Evaluation of hepatitis B virus in clinical trials of baricitinib in rheumatoid arthritis

Harigai, M., Winthrop, K., Takeuchi, T., Hsieh, T. Y., Chen, Y. M., Smolen, J. S., Burmester, G., Walls, C., Wu, W. S., Dickson, C., Liao, R. & Genovese, M. C., Feb 25 2020, In : RMD open. 6, 1, e001095.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Finding the relevance of antimicrobial stewardship for cystic fibrosis

Antimicrobial Resistance International Working Group in Cystic Fibrosis, Jul 2020, In : Journal of Cystic Fibrosis. 19, 4, p. 511-520 10 p.

Research output: Contribution to journalReview article

1 Scopus citations

Immunosuppression and the risk of readmission and mortality in patients with rheumatoid arthritis undergoing hip fracture, abdominopelvic and cardiac surgery

George, M. D., Baker, J. F., Winthrop, K. L., Goldstein, S. D., Alemao, E., Chen, L., Wu, Q., Xie, F. & Curtis, J. R., May 1 2020, In : Annals of the rheumatic diseases. 79, 5, 1 p.

Research output: Contribution to journalArticle

Incidence and prevalence of nontuberculous mycobacterial lung disease in a Large U.S. Managed Care Health Plan, 2008-2015

Winthrop, K. L., Marras, T. K., Adjemian, J., Zhang, H., Wang, P. & Zhang, Q., Jan 1 2020, In : Annals of the American Thoracic Society. 17, 2, p. 178-185 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Long-term effectiveness of live herpes zoster vaccine in patients with rheumatoid arthritis subsequently treated with tofacitinib

Winthrop, K. L., Wouters, A., Choy, E. H., Chen, C., Biswas, P., Wang, L., Soma, K., Needle, E., Valdez, H. & Rigby, W. F. C., May 1 2020, In : Annals of the rheumatic diseases. 79, 5, p. 669-671 3 p.

Research output: Contribution to journalLetter

Open Access

Mycobacteria and immunosuppression

Winthrop, K. L. & Roy, E. E., 2020, Handbook of Systemic Autoimmune Diseases. Elsevier Ltd, p. 83-107 25 p. (Handbook of Systemic Autoimmune Diseases; vol. 16).

Research output: Chapter in Book/Report/Conference proceedingChapter

Mycobacterial Infections Potentiated by Biologics

Calabrese, C. & Winthrop, K. L., Jun 2020, In : Infectious Disease Clinics of North America. 34, 2, p. 413-423 11 p.

Research output: Contribution to journalReview article

Safety profile of baricitinib for the treatment of rheumatoid arthritis over a median of 3 years of treatment: an updated integrated safety analysis

Genovese, M. C., Smolen, J. S., Takeuchi, T., Burmester, G., Brinker, D., Rooney, T. P., Zhong, J., Daojun, M., Saifan, C., Cardoso, A., Issa, M., Wu, W. S. & Winthrop, K. L., Jun 2020, In : The Lancet Rheumatology. 2, 6, p. e347-e357

Research output: Contribution to journalArticle

1 Scopus citations

Safety profile of baricitinib in Japanese patients with active rheumatoid arthritis with over 1.6 years median time in treatment: An integrated analysis of Phases 2 and 3 trials

Harigai, M., Takeuchi, T., Smolen, J. S., Winthrop, K. L., Nishikawa, A., Rooney, T. P., Saifan, C. G., Issa, M., Isaka, Y., Akashi, N., Ishii, T. & Tanaka, Y., Jan 2 2020, In : Modern Rheumatology. 30, 1, p. 36-43 8 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Treatment of nontuberculous mycobacterial pulmonary disease: an official ATS/ERS/ESCMID/IDSA clinical practice guideline

Daley, C. L., Iaccarino, J. M., Lange, C., Cambau, E., Wallace, R. J., Andrejak, C., Böttger, E. C., Brozek, J., Griffith, D. E., Guglielmetti, L., Huitt, G. A., Knight, S. L., Leitman, P., Marras, T. K., Olivier, K. N., Santin, M., Stout, J. E., Tortoli, E., van Ingen, J., Wagner, D. & 1 others, Winthrop, K. L., Jul 1 2020, In : The European respiratory journal. 56, 1

Research output: Contribution to journalArticle

Open Access

Unmet need in rheumatology: Reports from the Targeted Therapies meeting 2019

Winthrop, K. L., Weinblatt, M. E., Bathon, J., Burmester, G. R., Mease, P. J., Crofford, L., Bykerk, V., Dougados, M., Rosenbaum, J. T., Mariette, X., Sieper, J., Melchers, F., Cronstein, B. N., Breedveld, F. C., Kalden, J., Smolen, J. S. & Furst, D., Jan 1 2020, In : Annals of the rheumatic diseases. 79, 1, p. 88-93 6 p.

Research output: Contribution to journalReview article

Open Access
3 Scopus citations

Who Needs a Corona?

Winthrop, K. L., Jun 1 2020, In : Arthritis and Rheumatology. 72, 6, p. 874-876 3 p.

Research output: Contribution to journalComment/debate

Open Access
2 Scopus citations

‘Lady Windermere's counterpart? Pulmonary nontuberculous mycobacteria in men with bronchiectasis

Ku, J. H., Ranches, G., Siegel, S. A. R. & Winthrop, K. L., Feb 2020, In : Diagnostic Microbiology and Infectious Disease. 96, 2, 114916.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Advancing translational science for pulmonary nontuberculous mycobacterial infections: A road map for research

Daniel-Wayman, S., Abate, G., Barber, D. L., Bermudez, L. E., Coler, R. N., Cynamon, M. H., Daley, C. L., Davidson, R. M., Dick, T., Floto, R. A., Henkle, E., Holland, S. M., Jackson, M., Lee, R. E., Nuermberger, E. L., Olivier, K. N., Ordway, D. J., Prevots, D. R., Sacchettini, J. C., Salfinger, M. & 4 others, Sassetti, C. M., Sizemore, C. F., Winthrop, K. L. & Zelazny, A. M., Apr 2019, In : American journal of respiratory and critical care medicine. 199, 8, p. 947-951 5 p.

Research output: Contribution to journalReview article

10 Scopus citations

A systematic review and meta-analysis of infection risk with small molecule JAK inhibitors in rheumatoid arthritis

Bechman, K., Subesinghe, S., Norton, S., Atzeni, F., Galli, M., Cope, A. P., Winthrop, K. L. & Galloway, J. B., Oct 1 2019, In : Rheumatology (United Kingdom). 58, 10, p. 1755-1766 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Autoimmunity to bactericidal/permeability-increasing protein in bronchiectasis exhibits a requirement for Pseudomonas aeruginosa IgG response

Skopelja-Gardner, S., Theprungsirikul, J., Meagher, R. E., Beliveau, C. M., Bradley, K. E., Avery, M., Henkle, E., Siegel, S., Gifford, A. H., Winthrop, K. L. & Rigby, W. F. C., Feb 1 2019, In : European Respiratory Journal. 53, 2, 1801891.

Research output: Contribution to journalLetter

5 Scopus citations

Comparative risks of chronic inhaled corticosteroids and macrolides for bronchiectasis

Henkle, E., Curtis, J. R., Chen, L., Chan, B., Aksamit, T. R., Daley, C. L., Griffith, D. E. & Winthrop, K. L., Jul 1 2019, In : The European respiratory journal. 54, 1

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Direct-acting antivirals for hepatitis C: Predictors of early discontinuation in the real world

De Ávila Machado, M. A., De Moura, C. S., Klein, M., Winthrop, K., Carleton, B., Abrahamowicz, M., Feld, J., Curtis, J. R., Beauchamp, M. E. & Bernatsky, S., Jan 1 2019, In : Journal of Managed Care and Specialty Pharmacy. 25, 6, p. 697-704 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Evaluation of pneumococcal and tetanus vaccine responses in patients with rheumatoid arthritis receiving baricitinib: Results from a long-term extension trial substudy

Winthrop, K. L., Bingham, C. O., Komocsar, W. J., Bradley, J., Issa, M., Klar, R. & Kartman, C. E., Apr 18 2019, In : Arthritis Research and Therapy. 21, 1, 102.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Individualized decision aid for diverse women with lupus nephritis (IDEA-WON): A randomized controlled trial

Singh, J. A., Fraenkel, L., Green, C., Alarcón, G. S., Barton, J. L., Saag, K. G., Hanrahan, L. M., Raymond, S. C., Kimberly, R. P., Leong, A. L., Reyes, E., Street, R. L., Suarez-Almazor, M. E., Eakin, G. S., Marrow, L., Morgan, C. J., Caro, B., Sloan, J. A., Jandali, B., Garcia, S. R. & 8 others, Grossman, J., Winthrop, K. L., Trupin, L., Dall’era, M., Meara, A., Rizvi, T., Chatham, W. W. & Yazdany, J., May 2019, In : PLoS Medicine. 16, 5, e1002800.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2 Scopus citations

Long-term safety of certolizumab pegol in rheumatoid arthritis, axial spondyloarthritis, psoriatic arthritis, psoriasis and Crohn's disease: A pooled analysis of 11 317 patients across clinical trials

Curtis, J. R., Mariette, X., Gaujoux-Viala, C., Blauvelt, A., Kvien, T. K., Sandborn, W. J., Winthrop, K., De Longueville, M., Huybrechts, I. & Bykerk, V. P., May 1 2019, In : RMD open. 5, 1, e000942.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Long-Term Safety of Rituximab in Patients With Rheumatoid Arthritis: Results of a Five-Year Observational Study

Winthrop, K. L., Saag, K., Cascino, M. D., Pei, J., John, A., Jahreis, A., Haselkorn, T. & Furst, D. E., Aug 2019, In : Arthritis Care and Research. 71, 8, p. 993-1003 11 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Practice Patterns of Pneumocystis Pneumonia Prophylaxis in Connective Tissue Diseases: A Survey of Infectious Disease Physicians

Wolfe, R. M., Beekmann, S. E., Polgreen, P. M., Winthrop, K. L. & Peacock, J. E., Oct 5 2019, In : Open Forum Infectious Diseases. 6, 9, ofz315.

Research output: Contribution to journalArticle

Open Access

Prescribing patterns for treatment of mycobacterium avium complex and m. Xenopi pulmonary disease in ontario, canada, 2001–2013

Brode, S. K., Chung, H., Campitelli, M. A., Kwong, J. C., Marchand-Austin, A., Winthrop, K. L., Jamieson, F. B. & Marras, T. K., Jul 2019, In : Emerging infectious diseases. 25, 7, p. 1271-1280 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Risk for Herpes Zoster in Tofacitinib-Treated Rheumatoid Arthritis Patients With and Without Concomitant Methotrexate and Glucocorticoids

Curtis, J. R., Xie, F., Yang, S., Bernatsky, S., Chen, L., Yun, H. & Winthrop, K., Sep 1 2019, In : Arthritis Care and Research. 71, 9, p. 1249-1254 6 p.

Research output: Contribution to journalArticle

8 Scopus citations

Safety profile of baricitinib in patients with active rheumatoid arthritis with over 2 years median time in treatment

Smolen, J. S., Genovese, M. C., Takeuchi, T., Hyslop, D. L., Macias, W. L., Rooney, T., Chen, L., Dickson, C. L., Riddle Camp, J., Cardillo, T. E., Ishii, T. & Winthrop, K. L., Jan 1 2019, In : Journal of Rheumatology. 46, 1, p. 7-18 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Small-Molecule Protein Kinases Inhibitors and the Risk of Fungal Infections

Bechman, K., Galloway, J. B. & Winthrop, K. L., Dec 1 2019, In : Current Fungal Infection Reports. 13, 4, p. 229-243 15 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

The clinical features of bronchiectasis associated with alpha-1 antitrypsin deficiency, common variable immunodeficiency and primary ciliary dyskinesia-Results from the U.S. bronchiectasis research registry

Eden, E., Choate, R., Barker, A., Addrizzo-Harris, D., Aksamit, T. R., Daley, C. L., Daniels, M. L. A., DiMango, A., Fennelly, K., Griffith, D. E., Johnson, M. M., Knowles, M. R., Metersky, M. L., Noone, P. G., O'Donnell, A. E., Olivier, K. N., Salathe, M. A., Schmid, A., Thomashow, B., Tino, G. & 2 others, Turino, G. M. & Winthrop, K. L., 2019, In : Chronic Obstructive Pulmonary Diseases. 6, 2, p. 145-153 9 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

The Interface Between Digital Health and Rheumatology

Curtis, J. R., Michaud, K. & Winthrop, K., May 1 2019, In : Rheumatic Disease Clinics of North America. 45, 2, p. xv-xvi

Research output: Contribution to journalEditorial

Timing of Abatacept Before Elective Arthroplasty and Risk of Postoperative Outcomes

George, M. D., Baker, J. F., Winthrop, K., Alemao, E., Chen, L., Connolly, S., Hsu, J. Y., Simon, T. A., Wu, Q., Xie, F., Yang, S. & Curtis, J. R., Jan 1 2019, In : Arthritis Care and Research.

Research output: Contribution to journalArticle

3 Scopus citations

Unmet need in rheumatology: Reports from the Targeted Therapies meeting 2018

Winthrop, K. L., Weinblatt, M. E., Crow, M. K., Burmester, G. R., Mease, P. J., So, A. K., Bykerk, V., Van Vollenhoven, R. F., Dougados, M., Kay, J., Mariette, X., Sieper, J., Melchers, F., Cronstein, B. N., Shevach, E., Breedfeld, F. C., Kalden, J., Smolen, J. S. & Furst, D. E., Jul 1 2019, In : Annals of the rheumatic diseases. 78, 7, p. 872-878 7 p.

Research output: Contribution to journalReview article

7 Scopus citations

Ustekinumab use in patients with severe psoriasis co-infected with hepatitis B and/or C

Siegel, S. A. R., Winthrop, K., Ehst, B. B. & Ortega Loayza, A., Jan 1 2019, (Accepted/In press) In : British Journal of Dermatology.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Amikacin liposome inhalation suspension for treatment-refractory lung disease caused by Mycobacterium avium complex (CONVERT) a prospective, open-label, randomized study

Griffith, D. E., Eagle, G., Thomson, R., Aksamit, T. R., Hasegawa, N., Morimoto, K., Addrizzo-Harris, D. J., O'Donnell, A. E., Marras, T. K., Flume, P. A., Loebinger, M. R., Morgan, L., Codecasa, L. R., Hill, A. T., Ruoss, S. J., Yim, J. J., Ringshausen, F. C., Field, S. K., Philley, J. V., Wallace, R. J. & 4 others, Van Ingen, J., Coulter, C., Nezamis, J. & Winthrop, K. L., Dec 15 2018, In : American journal of respiratory and critical care medicine. 198, 12, p. 1559-1569 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Association between inhaled corticosteroid use and pulmonary nontuberculous mycobacterial infection

Liu, V. X., Winthrop, K., Lu, Y., Sharifi, H., Nasiri, H. U. & Ruoss, S. J., Oct 1 2018, In : Annals of the American Thoracic Society. 15, 10, p. 1169-1176 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Characteristics and Health-care Utilization History of Patients With Bronchiectasis in US Medicare Enrollees With Prescription Drug Plans, 2006 to 2014

Henkle, E., Chan, B., Curtis, J. R., Aksamit, T. R., Daley, C. L. & Winthrop, K. L., Dec 2018, In : CHEST. 154, 6, p. 1311-1320 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Effect of oral valproic acid vs placebo for vision loss in patients with autosomal dominant retinitis pigmentosa a randomized phase 2 multicenter placebo-controlled

Birch, D. G., Bernstein, P. S., Iannacone, A., Pennesi, M., Lam, B. L., Heckenlively, J., Csaky, K., Hartnett, M. E., Winthrop, K., Jayasundera, T., Hughbanks-Wheaton, D. K., Warner, J., Yang, P., Fish, G. E., Teske, M. P., Sklaver, N. L., Erker, L., Chegarnov, E., Smith, T., Wahle, A. & 8 others, VanVeldhuisen, P. C., McCormack, J., Lindblad, R., Bramer, S., Rose, S., Zilliox, P., Francis, P. J. & Weleber, R., Aug 1 2018, In : JAMA Ophthalmology. 136, 8, p. 849-856 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Epidemiology of nontuberculous mycobacterial infections in the U.S. Veterans Health Administration

Jones, M. M., Winthrop, K. L., Nelson, S. D., Duvall, S. L., Patterson, O. V., Nechodom, K. E., Findley, K. E., Radonovich, L. J., Samore, M. H. & Fennelly, K. P., Jun 2018, In : PloS one. 13, 6, 0197976.

Research output: Contribution to journalArticle

5 Scopus citations
52 Scopus citations

Herpes zoster infection in patients with ulcerative colitis receiving tofacitinib

Winthrop, K. L., Melmed, G. Y., Vermeire, S., Long, M. D., Chan, G., Pedersen, R. D., Lawendy, N., Thorpe, A. J., Nduaka, C. I. & Su, C., Oct 2018, In : Inflammatory Bowel Diseases. 24, 10, p. 2258-2265 8 p.

Research output: Contribution to journalArticle

45 Scopus citations

Impact of temporary methotrexate discontinuation for 2 weeks on immunogenicity of seasonal influenza vaccination in patients with rheumatoid arthritis: A randomised clinical trial

Park, J. K., Lee, Y. J., Shin, K., Ha, Y. J., Lee, E. Y., Song, Y. W., Choi, Y., Winthrop, K. & Lee, E. B., Jun 1 2018, In : Annals of the Rheumatic Diseases. 77, 6, p. 898-904 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Interaction between B-cell activation factor and methotrexate impacts immunogenicity of seasonal influenza vaccination in patients with rheumatoid arthritis

Park, J. K., Lee, Y. J., Bitoun, S., Winthrop, K., Choi, Y., Lee, E. B. & Mariette, X., Jan 1 2018, (Accepted/In press) In : Annals of the Rheumatic Diseases.

Research output: Contribution to journalArticle

1 Scopus citations
4 Scopus citations

Multicenter study of QuantiFERON®-TB Gold Plus in patients with active tuberculosis

Horne, D. J., Jones, B. E., Kamada, A., Fukushima, K., Winthrop, K. L., Siegel, S. A. R., Kovacs, A., Anthony, P., Meekin, K. A., Bhat, S., Kerndt, P., Chang, A., Koelle, D. M. & Narita, M., Jun 1 2018, In : International Journal of Tuberculosis and Lung Disease. 22, 6, p. 617-621 5 p.

Research output: Contribution to journalArticle

13 Scopus citations

Mycobacterial Disease: Evolving Concepts

Flume, P. A. & Winthrop, K., Jan 1 2018, In : Seminars in Respiratory and Critical Care Medicine. 39, 3, 1 p.

Research output: Contribution to journalEditorial

Pneumocystis and glucocorticoid use: To prophylax or not to prophylax (and when?); That is the question

Winthrop, K. & Baddley, J. W., May 1 2018, In : Annals of the Rheumatic Diseases. 77, 5, p. 631-633 3 p.

Research output: Contribution to journalEditorial

13 Scopus citations