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  • 2020
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  • Edward Neuwelt
2020

Diagnostic impact of preoperative corticosteroids in primary central nervous system lymphoma

Bullis, C. L., Maldonado-Perez, A., Bowden, S. G., Yaghi, N., Munger, D., Wood, M. D., Barajas, R. F., Ambady, P., Neuwelt, E. A. & Han, S. J., Feb 2020, In : Journal of Clinical Neuroscience. 72, p. 287-291 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Impact of maintenance rituximab on duration of response in primary central nervous system lymphoma

Ambady, P., Fu, R., Szidonya, L., Peereboom, D. M., Doolittle, N. & Neuwelt, E. A., Jan 1 2020, (Accepted/In press) In : Journal of Neuro-Oncology.

Research output: Contribution to journalReview article

1 Scopus citations
2019

Combined iron oxide nanoparticle ferumoxytol and gadolinium contrast enhanced MRI define glioblastoma pseudoprogression

Barajas, R. F., Hamilton, B. E., Schwartz, D., Mcconnell, H. L., Pettersson, D. R., Horvath, A., Szidonya, L., Varallyay, C. G., Firkins, J., Jaboin, J. J., Kubicky, C. D., Raslan, A. M., Dogan, A., Cetas, J. S., Ciporen, J., Han, S. J., Ambady, P., Muldoon, L. L., Woltjer, R., Rooney, W. D. & 1 others, Neuwelt, E. A., Mar 18 2019, In : Neuro-Oncology. 21, 4, p. 517-526 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Toll-like Receptor 4 Signaling and Downstream Neutrophilic Inflammation Mediate Endotoxemia-Enhanced Blood-Labyrinth Barrier Trafficking

Urdang, Z. D., Bills, J. L., Cahana, D. Y., Muldoon, L. L. & Neuwelt, E. A., Jan 1 2019, (Accepted/In press) In : Otology and Neurotology.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Blood-Brain Barrier Disruption Chemotherapy

McGregor, J. M., Bell, S. D., Doolittle, N., Murillo, T. P. & Neuwelt, E., Apr 24 2018, Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy: Second Edition. Elsevier Inc., p. 145-153 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Cerebral blood volume mapping with ferumoxytol in dynamic susceptibility contrast perfusion MRI: Comparison to standard of care

Varallyay, C. G., Nesbit, E., Horvath, A., Varallyay, P., Fu, R. R., Gahramanov, S., Muldoon, L., Li, X., Rooney, W. & Neuwelt, E., Jan 1 2018, (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

2 Scopus citations

Combination immunotherapy as a non-chemotherapy alternative for refractory or recurrent CNS lymphoma

Ambady, P., Szidonya, L., Firkins, J., James, J., Johansson, K., White, T., Jezierski, C., Doolittle, N. & Neuwelt, E., Jan 1 2018, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalArticle

2 Scopus citations

Neurovascular unit: Basic and clinical imaging with emphasis on advantages of ferumoxytol

Netto, J. P., Iliff, J., Stanimirovic, D., Krohn, K. A., Hamilton, B., Varallyay, C., Gahramanov, S., Daldrup-Link, H., D'Esterre, C., Zlokovic, B., Sair, H., Lee, Y., Taheri, S., Jain, R., Panigrahy, A., Reich, D. S., Drewes, L. R., Castillo, M. & Neuwelt, E., Jan 1 2018, In : Neurosurgery. 82, 6, p. 770-780 11 p.

Research output: Contribution to journalReview article

Open Access
9 Scopus citations

Sodium thiosulfate for protection from cisplatin-induced hearing loss

Brock, P. R., Maibach, R., Childs, M., Rajput, K., Roebuck, D., Sullivan, M. J., Laithier, V., Ronghe, M., Dall'Igna, P., Hiyama, E., Brichard, B., Skeen, J., Mateos, M. E., Capra, M., Rangaswami, A. A., Ansari, M., Rechnitzer, C., Veal, G. J., Covezzoli, A., Brugières, L. & 4 others, Perilongo, G., Czauderna, P., Morland, B. & Neuwelt, E. A., Jun 21 2018, In : New England Journal of Medicine. 378, 25, p. 2376-2385 10 p.

Research output: Contribution to journalArticle

51 Scopus citations
2017

Comprehensive review of the ThinkFirst injury prevention programs: A 30-Year success story for organized neurosurgery

Youngers, E. H., Zundel, K., Gerhardstein, D., Martínez, M., Bertrán, C., Proctor, M. R., Spatola, M. A. & Neuwelt, E. A., Sep 1 2017, In : Clinical Neurosurgery. 81, 3, p. 416-421 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Current and potential imaging applications of ferumoxytol for magnetic resonance imaging

Toth, G. B., Varallyay, C. G., Horvath, A., Bashir, M. R., Choyke, P. L., Daldrup-Link, H. E., Dosa, E., Finn, J. P., Gahramanov, S., Harisinghani, M., Macdougall, I., Neuwelt, A., Vasanawala, S. S., Ambady, P., Barajas, R., Cetas, J. S., Ciporen, J., DeLoughery, T. J., Doolittle, N. D., Fu, R. & 13 others, Grinstead, J., Guimaraes, A. R., Hamilton, B. E., Li, X., McConnell, H. L., Muldoon, L. L., Nesbit, G., Netto, J. P., Petterson, D., Rooney, W. D., Schwartz, D., Szidonya, L. & Neuwelt, E. A., Jul 2017, In : Kidney International. 92, 1, p. 47-66 20 p.

Research output: Contribution to journalReview article

73 Scopus citations

Dose escalation study of intravenous and intra-arterial N-acetylcysteine for the prevention of oto- and nephrotoxicity of cisplatin with a contrast-induced nephropathy model in patients with renal insufficiency

Dósa, E., Heltai, K., Radovits, T., Molnár, G., Kapocsi, J., Merkely, B., Fu, R., Doolittle, N. D., Tóth, G. B., Urdang, Z. & Neuwelt, E. A., Oct 3 2017, In : Fluids and Barriers of the CNS. 14, 1, 26.

Research output: Contribution to journalArticle

6 Scopus citations

Effects of sodium thiosulfate versus observation on development of cisplatin-induced hearing loss in children with cancer (ACCL0431): a multicentre, randomised, controlled, open-label, phase 3 trial

Freyer, D. R., Chen, L., Krailo, M. D., Knight, K., Villaluna, D., Bliss, B., Pollock, B. H., Ramdas, J., Lange, B., Van Hoff, D., VanSoelen, M. L., Wiernikowski, J., Neuwelt, E. A. & Sung, L., Jan 1 2017, In : The Lancet Oncology. 18, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors

Ambady, P., Wu, Y. J., Walker, J. M., Kersch, C., Pagel, M. A., Woltjer, R. R., Fu, R. R., Muldoon, L. & Neuwelt, E., Aug 1 2017, In : Cancer Gene Therapy. 24, 8, p. 348-357 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Group-Wide, Prospective Study of Ototoxicity Assessment in Children Receiving Cisplatin Chemotherapy (ACCL05C1): A Report From the Children's Oncology Group

Knight, K. R., Chen, L., Freyer, D., Aplenc, R., Bancroft, M., Bliss, B., Dang, H., Gillmeister, B., Hendershot, E., Kraemer, D. F., Lindenfeld, L., Meza, J., Neuwelt, E. A., Pollock, B. H. & Sung, L., Feb 1 2017, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 35, 4, p. 440-445 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

High αv integrin level of cancer cells is associated with development of brain metastasis in athymic rats

Wu, Y. J., Pagel, M. A., Muldoon, L., Fu, R. R. & Neuwelt, E., Aug 1 2017, In : Anticancer Research. 37, 8, p. 4029-4040 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
13 Scopus citations

Pseudo-extravasation rate constant of dynamic susceptibility contrast-MRI determined from pharmacokinetic first principles

Li, X., Varallyay, C. G., Gahramanov, S., Fu, R. R., Rooney, W. & Neuwelt, E., 2017, (Accepted/In press) In : NMR in Biomedicine.

Research output: Contribution to journalArticle

Quantitative comparison of delayed ferumoxytol T1 enhancement with immediate gadoteridol enhancement in high grade gliomas

Horváth, A., Varallyay, C. G., Schwartz, D., Toth, G. B., Netto, J. P., Barajas, R., Várallyay, P., Szidonya, L., Firkins, J., Youngers, E., Fu, R. R., Ambady, P., Bogner, P. & Neuwelt, E., Jan 1 2017, (Accepted/In press) In : Magnetic Resonance in Medicine.

Research output: Contribution to journalArticle

4 Scopus citations

The translational significance of the neurovascular unit

McConnell, H. L., Kersch, C. N., Woltjer, R. R. & Neuwelt, E., Jan 20 2017, In : Journal of Biological Chemistry. 292, 3, p. 762-770 9 p.

Research output: Contribution to journalReview article

75 Scopus citations

What does the boxed warning tell us? Safe practice of using ferumoxytol as an MRI CONTRAST AGENT

Varallyay, C. G., Toth, G. B., Fu, R. R., Netto, J. P., Firkins, J., Ambady, P. & Neuwelt, E., Jul 1 2017, In : American Journal of Neuroradiology. 38, 7, p. 1297-1302 6 p.

Research output: Contribution to journalArticle

21 Scopus citations
2016

Ferumoxytol-enhanced MRI differentiation of meningioma from dural metastases: a pilot study with immunohistochemical observations

Hamilton, B., Woltjer, R. R., Prola-Netto, J., Nesbit, G., Gahramanov, S., Pham, T., Wagner, J. & Neuwelt, E., Jul 8 2016, (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-9 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ferumoxytol nanoparticle uptake in brain during acute neuroinflammation is cell-specific

McConnell, H. L., Schwartz, D. L., Richardson, B. E., Woltjer, R. R., Muldoon, L. & Neuwelt, E., Aug 1 2016, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 12, 6, p. 1535-1542 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
11 Scopus citations
3 Scopus citations

Outwitting the Blood-Brain Barrier

Neuwelt, E., Ambady, P., Muldoon, L., McConnell, H. & Doolittle, N., Nov 15 2016, In : Oncology (Williston Park, N.Y.). 30, 11

Research output: Contribution to journalArticle

2 Scopus citations

Safety Report of Ferumoxytol for Magnetic Resonance Imaging in Children and Young Adults

Muehe, A. M., Feng, D., Von Eyben, R., Luna-Fineman, S., Link, M. P., Muthig, T., Huddleston, A. E., Neuwelt, E. A. & Daldrup-Link, H. E., Apr 1 2016, In : Investigative Radiology. 51, 4, p. 221-227 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

Therapy for secondary CNS involvement inmalignant lymphomas: No standard yet!

Korfel, A., Chamberlain, M., Neuwelt, E., Thiel, E., Doolittle, N., Schlegel, U., Dreyling, M., Rubenstein, J., Fischer, L., Björkholm, M., Martus, P., Weller, M. & Glantz, M., May 20 2016, In : Journal of Clinical Oncology. 34, 15, p. 1829-1830 2 p.

Research output: Contribution to journalLetter

3 Scopus citations