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  • John Nutt
2020

Aromatic L-Amino Acid Decarboxylase Gene Therapy Enhances Levodopa Response in Parkinson's Disease

Nutt, J. G., Curtze, C., Hiller, A., Anderson, S., Larson, P. S., Van Laar, A. D., Richardson, R. M., Thompson, M. E., Sedkov, A., Leinonen, M., Ravina, B., Bankiewicz, K. S. & Christine, C. W., May 1 2020, In : Movement Disorders. 35, 5, p. 851-858 8 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cognitively Challenging Agility Boot Camp Program for Freezing of Gait in Parkinson Disease

King, L. A., Mancini, M., Smulders, K., Harker, G., Lapidus, J., Ramsey, K., Carlson-Kuhta, P., Fling, B., Nutt, J. G., Peterson, D. S. & Horak, F. B., May 1 2020, In : Neurorehabilitation and Neural Repair. 34, 5, p. 417-427 11 p.

Research output: Contribution to journalArticle

Quantity and quality of gait and turning in people with multiple sclerosis, Parkinson’s disease and matched controls during daily living

Shah, V. V., McNames, J., Mancini, M., Carlson-Kuhta, P., Spain, R., Nutt, J. G., El-Gohary, M., Curtze, C. & Horak, F. B., Apr 1 2020, In : Journal of Neurology. 267, 4, p. 1188-1196 9 p.

Research output: Contribution to journalArticle

2019

A Two-Stage Tremor Detection Algorithm for Wearable Inertial Sensors during Normal Daily Activities

McNames, J., Shah, V. V., Mancini, M., Curtze, C., El-Gohary, M., Aboy, M., Carlson-Kuhta, P., Nutt, J. G. & Horak, F., Jul 2019, 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019. Institute of Electrical and Electronics Engineers Inc., p. 2535-2538 4 p. 8857133. (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Effects of augmenting cholinergic neurotransmission on balance in Parkinson's disease

Mancini, M., Chung, K., Zajack, A., Martini, D. N., Ramsey, K., Lapidus, J., Horak, F. B. & Nutt, J. G., Dec 2019, In : Parkinsonism and Related Disorders. 69, p. 40-47 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

How to select balance measures sensitive to parkinson’s disease from body-worn inertial sensors—separating the trees from the forest

Hasegawa, N., Shah, V. V., Carlson-Kuhta, P., Nutt, J. G., Horak, F. B. & Mancini, M., Aug 1 2019, In : Sensors (Switzerland). 19, 15, 3320.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Magnetic Resonance Imaging–Guided Phase 1 Trial of Putaminal AADC Gene Therapy for Parkinson's Disease

Christine, C. W., Bankiewicz, K. S., Van Laar, A. D., Richardson, R. M., Ravina, B., Kells, A. P., Boot, B., Martin, A. J., Nutt, J., Thompson, M. E. & Larson, P. S., Jan 1 2019, In : Annals of Neurology.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Overview of the cholinergic contribution to gait, balance and falls in Parkinson's disease

Morris, R., Martini, D. N., Madhyastha, T., Kelly, V. E., Grabowski, T. J., Nutt, J. & Horak, F., Jun 2019, In : Parkinsonism and Related Disorders. 63, p. 20-30 11 p.

Research output: Contribution to journalReview article

9 Scopus citations
2018

Apraxia of gait- or apraxia of postural transitions?

Dale, M., Curtze, C. & Nutt, J., Jan 1 2018, (Accepted/In press) In : Parkinsonism and Related Disorders.

Research output: Contribution to journalArticle

1 Scopus citations

Assessment of the ability of open- and closed-loop cueing to improve turning and freezing in people with Parkinson’s disease

Mancini, M., Smulders, K., Harker, G., Stuart, S. & Nutt, J., Dec 1 2018, In : Scientific Reports. 8, 1, 12773.

Research output: Contribution to journalArticle

17 Scopus citations

A wrinkle in ON-time - A GI structural abnormality confounding levodopa therapy with Duodopa rescue; a case study

Staisch, J., Bakis, G. & Nutt, J., May 1 2018, In : Parkinsonism and Related Disorders. 50, p. 130-131 2 p.

Research output: Contribution to journalLetter

3 Scopus citations

Case studies in neuroscience: a dissociation of balance and posture demonstrated by camptocormia

St George, R. J., Gurfinkel, V. S., Kraakevik, J., Nutt, J. G. & Horak, F. B., Jan 2018, In : Journal of neurophysiology. 119, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Gait stability has phase-dependent dual-task costs in Parkinson's disease

Fino, P. C., Mancini, M., Curtze, C., Nutt, J. G. & Horak, F. B., May 30 2018, In : Frontiers in Neurology. 9, MAY, 373.

Research output: Contribution to journalArticle

5 Scopus citations

Neurological disorders of gait, balance and posture: A sign-based approach

Nonnekes, J., Goselink, R. J. M., Růzicka, E., Fasano, A., Nutt, J. & Bloem, B. R., Mar 1 2018, In : Nature Reviews Neurology. 14, 3, p. 183-189 7 p.

Research output: Contribution to journalReview article

19 Scopus citations

Non-dopaminergic therapies

Nutt, J. G. & Bohnen, N. I., 2018, In : Journal of Parkinson's Disease. 8, s1, p. S73-S78

Research output: Contribution to journalReview article

3 Scopus citations

The Impact of Freezing of Gait on Balance Perception and Mobility in Community-Living with Parkinson'S Disease

Mancini, M., Curtze, C., Stuart, S., El-Gohary, M., McNames, J., Nutt, J. & Horak, F., Oct 26 2018, 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2018. Institute of Electrical and Electronics Engineers Inc., Vol. 2018-July. p. 3040-3043 4 p. 8512910

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations
2017

Dual task interference on postural sway, postural transitions and gait in people with Parkinson's disease and freezing of gait

de Souza Fortaleza, A. C., Mancini, M., Carlson-Kuhta, P., King, L., Nutt, J., Chagas, E. F., Freitas, I. F. & Horak, F., Jul 1 2017, In : Gait and Posture. 56, p. 76-81 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

Impaired perception of surface tilt in progressive supranuclear palsy

Dale, M. L., Horak, F. B., Wright, W. G., Schoneburg, B. M., Nutt, J. G. & Mancini, M., Mar 2017, In : PloS one. 12, 3, e0173351.

Research output: Contribution to journalArticle

4 Scopus citations

Investigation of anticipatory postural adjustments during One-Leg Stance using inertial sensors: Evidence from subjects with Parkinsonism

Bonora, G., Mancini, M., Carpinella, I., Chiari, L., Ferrarin, M., Nutt, J. G. & Horak, F. B., Jul 25 2017, In : Frontiers in Neurology. 8, JUL, 361.

Research output: Contribution to journalArticle

6 Scopus citations

Recovery from multiple apas delays gait initiation in parkinson’s disease

Cohen, R. G., Nutt, J. G. & Horak, F. B., Feb 14 2017, In : Frontiers in Human Neuroscience. 11, 60.

Research output: Contribution to journalArticle

11 Scopus citations

The clinical significance of freezing while turning in Parkinson's disease

Mancini, M., Smulders, K., Cohen, R. G., Horak, F., Giladi, N. & Nutt, J., Feb 20 2017, In : Neuroscience. 343, p. 222-228 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Trial of dextromethorphan/quinidine to treat levodopa-induced dyskinesia in Parkinson's disease

Fox, S. H., Metman, L. V., Nutt, J., Brodsky, M., Factor, S. A., Lang, A. E., Pope, L. E., Knowles, N. & Siffert, J., 2017, (Accepted/In press) In : Movement Disorders.

Research output: Contribution to journalArticle

12 Scopus citations
2016

Associations between mobility, cognition and callosal integrity in people with parkinsonism

Fling, B., Dale, M., Curtze, C., Smulders, K., Nutt, J. & Horak, F., 2016, In : NeuroImage: Clinical. 11, p. 415-422 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Balance and gait represent independent domains of mobility in Parkinson disease

Horak, F., Mancini, M., Carlson-Kuhta, P., Nutt, J. & Salarian, A., Sep 1 2016, In : Physical Therapy. 96, 9, p. 1364-1371 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Motor subtype in Parkinson's disease: Different disorders or different stages of disease?

Nutt, J., Jul 1 2016, In : Movement Disorders. 31, 7, p. 957-961 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

Objective gait and balance impairments relate to balance confidence and perceived mobility in people with parkinson disease

Curtze, C., Nutt, J., Carlson-Kuhta, P., Mancini, M. & Horak, F., Nov 1 2016, In : Physical Therapy. 96, 11, p. 1734-1743 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Pharmacological treatment in Parkinson's disease: Effects on gait

Smulders, K., Dale, M., Carlson-Kuhta, P., Nutt, J. & Horak, F., Oct 1 2016, In : Parkinsonism and Related Disorders. 31, p. 3-13 11 p.

Research output: Contribution to journalReview article

43 Scopus citations

Quantifying effects of age on balance and gait with inertial sensors in community-dwelling healthy adults

Park, J. H., Mancini, M., Carlson-Kuhta, P., Nutt, J. & Horak, F., Dec 1 2016, In : Experimental Gerontology. 85, p. 48-58 11 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015

Continuous levodopa infusion is better-for now

Nutt, J. G., Apr 1 2015, In : Movement Disorders. 30, 4, p. 443-445 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Continuous monitoring of turning in Parkinson's disease: Rehabilitation potential

Mancini, M., El-Gohary, M., Pearson, S., Mcnames, J., Schlueter, H., Nutt, J. G., King, L. A. & Horak, F. B., Aug 22 2015, In : NeuroRehabilitation. 37, 1, p. 3-10 8 p.

Research output: Contribution to journalArticle

62 Scopus citations

Do cognitive measures and brain circuitry predict outcomes of exercise in Parkinson Disease: A randomized clinical trial

King, L. A., Peterson, D. S., Mancini, M., Carlson-Kuhta, P., Fling, B. W., Smulders, K., Nutt, J. G., Dale, M., Carter, J., Winters-Stone, K. M. & Horak, F. B., Oct 24 2015, In : BMC Neurology. 15, 1, 218.

Research output: Contribution to journalArticle

13 Scopus citations

Dual-task interference and brain structural connectivity in people with Parkinson's disease who freeze

Peterson, D. S., Fling, B. W., Mancini, M., Cohen, R. G., Nutt, J. G. & Horak, F. B., Jul 1 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 7, p. 786-792 7 p.

Research output: Contribution to journalArticle

43 Scopus citations

Effect of augmenting cholinergic function on gait and balance

Mancini, M., Fling, B., Gendreau, A., Lapidus, J., Horak, F., Chung, K. K. & Nutt, J., Dec 23 2015, In : BMC Neurology. 15, 1, 264.

Research output: Contribution to journalArticle

12 Scopus citations

Effects of group, individual, and home exercise in persons with Parkinson disease: A randomized clinical trial

King, L. A., Wilhelm, J., Chen, Y., Blehm, R., Nutt, J., Chen, Z., Serdar, A. & Horak, F. B., Oct 1 2015, In : Journal of Neurologic Physical Therapy. 39, 4, p. 204-212 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Freezing of gait: A practical approach to management

Nonnekes, J., Snijders, A. H., Nutt, J. G., Deuschl, G., Giladi, N. & Bloem, B. R., Jul 1 2015, In : The Lancet Neurology. 14, 7, p. 768-778 11 p.

Research output: Contribution to journalComment/debate

123 Scopus citations

Levodopa Is a Double-Edged Sword for Balance and Gait in People With Parkinson's Disease

Curtze, C., Nutt, J. G., Carlson-Kuhta, P., Mancini, M. & Horak, F. B., Sep 1 2015, In : Movement Disorders. 30, 10, p. 1361-1370 10 p.

Research output: Contribution to journalArticle

115 Scopus citations

Life-sustaining treatment orders, location of death and co-morbid conditions in decedents with Parkinson's disease

Tuck, K. K., Zive, D. M., Schmidt, T. A., Carter, J., Nutt, J. & Fromme, E. K., Oct 1 2015, In : Parkinsonism and Related Disorders. 21, 10, p. 1205-1209 5 p., 2744.

Research output: Contribution to journalArticle

11 Scopus citations

Neuropsychological changes following deep brain stimulation surgery for Parkinson's disease: Comparisons of treatment at pallidal and subthalamic targets versus best medical therapy

Rothlind, J. C., York, M. K., Carlson, K., Luo, P., Marks, W. J., Weaver, F. M., Stern, M., Follett, K., Reda, D., Chairpersons, K. F., Ippolito, D., Stoner, G., Barnett, T., Bukowski, K., De Nicolo, R., Hur, K., Jimenez, J., Motyka, J., Simon, T., Thakkar, B. & 99 others, Woolson, R., Fye, C., Gagne, W., Harris, C., Heemskerk, J., Moy, C., Sheehy, P., O'Leary, T., Huang, G. D., Fiore, L., Hall, R., Stroupe, K., Burchiel, K., Koller, W., Pahwa, R., Sagher, O., Bakay, R., Chappell, R., Hart, R., Holloway, R., McCabe, G., Schenkman, M., Taha, J., Buckelew, J., Garin, M., Matzek, S., Smith, D., Bronstein, J., Duda, J., Hogarth, P., Horn, S., Lai, E. C., Samii, A., Atassi, F., Bello, C., Bunting-Perry, L., Conn, T., Cugley, A., Eubank, N., Fincher, L., Franks, R., Harris, T., Haselman, M., Heath, S., Hirsch, M., Janovsky, V., Lanier, E., Lloyd, M., Loehner, S., O'Connor, S., Ordonez, L., Maccarone, H., Massey-Makhoul, K., Matthews, M., Meyn, E., Mimura, K., Morrow, W., Searles, T., Valotta, J., Vasthare, U., Volz, M., Ward, C., Warker, R., Watson, H., Willson, P., Baron, M., Brodsky, M., Calabrese, V., Campbell, G., Colcher, A., Farag, E., Henry, E., Hou, J. G., Kang, G., Kleiner-Fisman, G., Kraakevik, J., Nutt, J., Ostrem, J., Sarwar, A., Subramanian, I., Vanek, Z., Baltuch, G., De Salles, A., Eller, J., Holloway, K., Larson, P., Simpson, R., Starr, P., Carne, W., Erikson, T., Kreutzer, J., Mendez, M., Moberg, P., Ragland, J., Seel, R., Soety, E., Storzbach, D., Troster, A. & Jaggi, J., Jun 1 2015, In : Journal of Neurology, Neurosurgery and Psychiatry. 86, 6, p. 622-629 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Preferences of Patients With Parkinson’s Disease for Communication About Advanced Care Planning

Tuck, K. K., Brod, L., Nutt, J. & Fromme, E. K., Feb 19 2015, In : American Journal of Hospice and Palliative Medicine. 32, 1, p. 68-77 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Reply: Does dominant pedunculopontine nucleus exist?

Fling, B. W., Nutt, J. G. & Horak, F. B., Feb 1 2015, In : Brain. 138, 2, p. e324

Research output: Contribution to journalLetter

2 Scopus citations

Reply: Does dominant pedunculopontine nucleus exist? Probably not

Fling, B. W., Nutt, J. G. & Horak, F. B., May 1 2015, In : Brain. 138, 5, p. e347

Research output: Contribution to journalLetter

The relationship between obsessive-compulsive symptoms and PARKIN genotype: The CORE-PD study

Sharp, M. E., Caccappolo, E., Mejia-Santana, H., Tang, M. X., Rosado, L., Orbe Reilly, M., Ruiz, D., Louis, E. D., Comella, C., Nance, M., Bressman, S., Scott, W. K., Tanner, C., Waters, C., Fahn, S., Cote, L., Ford, B., Rezak, M., Novak, K., Friedman, J. H. & 12 others, Pfeiffer, R., Payami, H., Molho, E., Factor, S. A., Nutt, J., Serrano, C., Arroyo, M., Pauciulo, M. W., Nichols, W. C., Clark, L. N., Alcalay, R. N. & Marder, K. S., Feb 1 2015, In : Movement Disorders. 30, 2, p. 278-283 6 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

A randomized clinical trial of high-dosage coenzyme Q10 in early parkinson disease no evidence of benefit

The Parkinson Study Group QE3 Investigators, 2014, In : JAMA Neurology. 75, 1, p. 543-552 10 p.

Research output: Contribution to journalArticle

153 Scopus citations

Cognitive and motor function in long-duration PARKIN-associated parkinson disease

Alcalay, R. N., Caccappolo, E., Mejia-Santana, H., Tang, M. X., Rosado, L., Reilly, M. O., Ruiz, D., Louis, E. D., Comella, C. L., Nance, M. A., Bressman, S. B., Scott, W. K., Tanner, C. M., Mickel, S. F., Waters, C. H., Fahn, S., Cote, L. J., Frucht, S. J., Ford, B., Rezak, M. & 16 others, Novak, K. E., Friedman, J. H., Pfeiffer, R. F., Marsh, L., Hiner, B., Payami, H., Molho, E., Factor, S. A., Nutt, J. G., Serrano, C., Arroyo, M., Ottman, R., Pauciulo, M. W., Nichols, W. C., Clark, L. N. & Marder, K. S., Jan 2014, In : JAMA Neurology. 71, 1, p. 62-67 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Comorbidity and functional mobility in persons with Parkinson disease

King, L. A., Priest, K. C., Nutt, J., Chen, Y., Chen, Z., Melnick, M. & Horak, F., Nov 1 2014, In : Archives of Physical Medicine and Rehabilitation. 95, 11, p. 2152-2157 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Deep brain stimulation may improve quality of life in people with parkinson's disease without affecting caregiver burden

Oyama, G., Okun, M. S., Schmidt, P., Tröster, A. I., Nutt, J., Go, C. L., Foote, K. D. & Malaty, I. A., Feb 2014, In : Neuromodulation. 17, 2, p. 126-132 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Dual tasking during postural stepping responses increases falls but not freezing in people with Parkinson's disease

Jacobs, J. V., Nutt, J. G., Carlson-Kuhta, P., Allen, R. & Horak, F. B., Jul 2014, In : Parkinsonism and Related Disorders. 20, 7, p. 779-781 3 p.

Research output: Contribution to journalArticle

18 Scopus citations

Functional reorganization of the locomotor network in parkinson patients with freezing of gait

Fling, B. W., Cohen, R. G., Mancini, M., Carpenter, S. D., Fair, D. A., Nutt, J. G. & Horak, F. B., Jun 17 2014, In : PloS one. 9, 6, e100291.

Research output: Contribution to journalArticle

105 Scopus citations

Inhibition, executive function, and freezing of gait

Cohen, R. G., Klein, K. A., Nomura, M., Fleming, M., Mancini, M., Giladi, N., Nutt, J. G. & Horak, F. B., 2014, In : Journal of Parkinson's Disease. 4, 1, p. 111-122 12 p.

Research output: Contribution to journalArticle

43 Scopus citations