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  A comprehensive evaluation of biomarkers predictive of response to PI3K inhibitors and of resistance mechanisms in head and neck squamous cell carcinoma

  Mazumdar, T., Byers, L. A., Ng, P. K. S., Mills, G. B., Peng, S., Diao, L., Fan, Y. H., Stemke-Hale, K., Heymach, J. V., Myers, J. N., Glisson, B. S. & Johnson, F. M., Nov 1 2014, In: Molecular cancer therapeutics. 13, 11, p. 2738-2750 13 p.

  Research output: Contribution to journal › Article › peer-review
  57 Scopus citations

• A comprehensive excitatory input map of the striatum reveals novel functional organization

  Hunnicutt, B. J., Jongbloets, B. C., Birdsong, W. T., Gertz, K. J., Zhong, H. & Mao, T., Nov 28 2016, In: eLife. 5, November2016, e19103.

  Research output: Contribution to journal › Article › peer-review
  190 Scopus citations

• A comprehensive iterative approach is highly effective in diagnosing individuals who are exome negative

  Undiagnosed Diseases Network, Jan 1 2019, In: Genetics in Medicine. 21, 1, p. 161-172 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  40 Scopus citations

• A comprehensive molecular cytogenetic analysis of chromosome rearrangements in gibbons

  Capozzi, O., Carbone, L., Stanyon, R. R., Marra, A., Yang, F., Whelan, C. W., De Jong, P. J., Rocchi, M. & Archidiacono, N., Dec 2012, In: Genome Research. 22, 12, p. 2520-2528 9 p.

  Research output: Contribution to journal › Article › peer-review
  23 Scopus citations

• A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

  The Cancer Genome Atlas Research Network, Apr 9 2018, In: Cancer Cell. 33, 4, p. 690-705.e9

  Research output: Contribution to journal › Article › peer-review

  Open Access
  249 Scopus citations

• A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

  Krepler, C., Sproesser, K., Brafford, P., Beqiri, M., Garman, B., Xiao, M., Shannan, B., Watters, A., Perego, M., Zhang, G., Vultur, A., Yin, X., Liu, Q., Anastopoulos, I. N., Wubbenhorst, B., Wilson, M. A., Xu, W., Karakousis, G., Feldman, M., Xu, X. & 34 others, Amaravadi, R., Gangadhar, T. C., Elder, D. E., Haydu, L. E., Wargo, J. A., Davies, M. A., Lu, Y., Mills, G. B., Frederick, D. T., Barzily-Rokni, M., Flaherty, K. T., Hoon, D. S., Guarino, M., Bennett, J. J., Ryan, R. W., Petrelli, N. J., Shields, C. L., Terai, M., Sato, T., Aplin, A. E., Roesch, A., Darr, D., Angus, S., Kumar, R., Halilovic, E., Caponigro, G., Jeay, S., Wuerthner, J., Walter, A., Ocker, M., Boxer, M. B., Schuchter, L., Nathanson, K. L. & Herlyn, M., Nov 14 2017, In: Cell Reports. 21, 7, p. 1953-1967 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  77 Scopus citations

• A Comprehensive Review of Complication Rates after Surgery for Adult Deformity: A Reference for Informed Consent

  Sciubba, D. M., Yurter, A., Smith, J. S., Kelly, M. P., Scheer, J. K., Goodwin, C. R., Lafage, V., Hart, R. A., Bess, S., Kebaish, K., Schwab, F., Shaffrey, C. I. & Ames, C. P., 2015, In: Spine Deformity. 3, 6, p. 575-594 20 p.

  Research output: Contribution to journal › Article › peer-review
  71 Scopus citations

• A comprehensive review of cross-sectional imaging of the nasolacrimal drainage apparatus: What radiologists need to know

  Raslan, O. A., Ozturk, A., Pham, N., Chang, J., Strong, E. B. & Bobinski, M., Jan 1 2019, In: American Journal of Roentgenology. 213, 6, p. 1331-1340 10 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• A comprehensive review of exceptional responders to anticancer drugs in the biomedical literature

  Nishikawa, G., Luo, J. & Prasad, V., Sep 2018, In: European Journal of Cancer. 101, p. 143-151 9 p.

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• A comprehensive review of randomized clinical trials in three medical journals reveals 396 medical reversals

  Herrera-Perez, D., Haslam, A., Crain, T., Gill, J., Livingston, C., Kaestner, V., Hayes, M., Morgan, D., Cifu, A. S. & Prasad, V., Jun 2019, In: eLife. 8, e45183.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  51 Scopus citations

• A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ

  Yamanaka, K., Dorjsuren, D., Eoff, R. L., Egli, M., Maloney, D. J., Jadhav, A., Simeonov, A. & Lloyd, R. S., Oct 8 2012, In: PloS one. 7, 10, e45032.

  Research output: Contribution to journal › Article › peer-review
  30 Scopus citations

• A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells

  Rix, U., Remsing Rix, L. L., Terker, A. S., Fernbach, N. V., Hantschel, O., Planyavsky, M., Breitwieser, F. P., Herrmann, H., Colinge, J., Bennett, K. L., Augustin, M., Till, J. H., Heinrich, M. C., Valent, P. & Superti-Furga, G., Jan 2010, In: Leukemia. 24, 1, p. 44-50 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  65 Scopus citations

• A comprehensive thalamocortical projection map at the mesoscopic level

  Hunnicutt, B. J., Long, B. R., Kusefoglu, D., Gertz, K. J., Zhong, H. & Mao, T., Sep 1 2014, In: Nature Neuroscience. 17, 9, p. 1276-1285 10 p.

  Research output: Contribution to journal › Article › peer-review
  71 Scopus citations

• A computational model for asynchronous oocyte growth dynamics in a batch-spawning fish

  Li, Z., Villeneuve, D. L., Jensen, K. M., Ankley, G. T. & Watanabe, K. H., Sep 1 2011, In: Canadian Journal of Fisheries and Aquatic Sciences. 68, 9, p. 1528-1538 11 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• A computational model of the hypothalamic - pituitary - gonadal axis in female fathead minnows (Pimephales promelas) exposed to 17α-ethynylestradiol and 17β-trenbolone

  Li, Z., Kroll, K. J., Jensen, K. M., Villeneuve, D. L., Ankley, G. T., Brian, J. V., Sepúlveda, M. S., Orlando, E. F., Lazorchak, J. M., Kostich, M., Armstrong, B., Denslow, N. D. & Watanabe, K. H., May 5 2011, In: BMC systems biology. 5, 63.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  36 Scopus citations

• A computational model of the hypothalamic-pituitary-gonadal axis in male fathead minnows exposed to 17α-ethinylestradiol and 17β-estradiol

  Watanabe, K. H., Li, Z., Kroll, K. J., Villeneuve, D. L., Garcia-Reyero, N., Orlando, E. F., Sepúlveda, M. S., Collette, T. W., Ekman, D. R., Ankley, G. T. & Denslow, N. D., 2009, In: Toxicological Sciences. 109, 2, p. 180-192 13 p.

  Research output: Contribution to journal › Article › peer-review
  36 Scopus citations

• A computational pipeline for protein structure prediction and analysis at genome scale

  Shah, M., Passovets, S., Kim, D., Ellrott, K., Wang, L., Vokler, I., LoCascio, P., Xu, D. & Xu, Y., Oct 12 2003, In: Bioinformatics. 19, 15, p. 1985-1996 12 p.

  Research output: Contribution to journal › Article › peer-review
  16 Scopus citations

• A computed tomography-based coronary lesion score to predict acute coronary syndrome among patients with acute chest pain and significant coronary stenosis on coronary computed tomographic angiogram

  Ferencik, M., Schlett, C. L., Ghoshhajra, B. B., Kriegel, M. F., Joshi, S. B., Maurovich-Horvat, P., Rogers, I. S., Banerji, D., Bamberg, F., Truong, Q. A., Brady, T. J., Nagurney, J. T. & Hoffmann, U., Jul 15 2012, In: American Journal of Cardiology. 110, 2, p. 183-189 7 p.

  Research output: Contribution to journal › Article › peer-review
  54 Scopus citations

• A Computer-aided Approach for the Quantitation of Regional Left Ventricular Function Using Two-dimensional Echocardiography

  Sklenar, J., Jayaweera, A. R. & Kaul, S., 1992, In: Journal of the American Society of Echocardiography. 5, 1, p. 33-40 8 p.

  Research output: Contribution to journal › Article › peer-review
  39 Scopus citations

• A computer-based assessment detects regimen misunderstandings and nonadherence for patients on HIV antiretroviral therapy

  Bangsberg, D. R., Bronstone, A. & Hofmann, R., Feb 5 2002, In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. 14, 1, p. 3-15 13 p.

  Research output: Contribution to journal › Article › peer-review
  46 Scopus citations

• A Computer-Based Method of Filing Photographs and Procedures

  Allan, J. H. & Cook, T. A., Mar 1985, In: Archives of Otolaryngology. 111, 3, p. 178-181 4 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• A computer-based training intervention for work supervisors to respond to intimate partner violence

  Glass, N., Bloom, T., Perrin, N. & Anger, W. K., Dec 2010, In: Safety and Health at Work. 1, 2, p. 167-174 8 p.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• A concept analysis of adolescent friendship

  Roach, A., 2019, In: Nursing forum. 54, 3, p. 328-335 8 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• A Conceptual Framework and Key Research Questions in Educational Needs of Blood and Marrow Transplantation Patients, Caregivers, and Families

  Schoemans, H. M., Finn, L., Foster, J., Roche-Green, A., Bevans, M., Kullberg, S., Lee, E., Sargeant, C., Schatz, B. A., Scheeler, K., Shaw, B. E., Shereck, E., Murphy, E. A., Burns, L. J. & Schmit-Pokorny, K., Jul 2019, In: Biology of Blood and Marrow Transplantation. 25, 7, p. 1416-1423 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Scopus citations

• A conceptual framework encompassing the psychoneuroimmunoendocrinological influences of listening to music in patients with heart failure

  Burrai, F., Hasan, W., Luppi, M. & Micheluzzi, V., Jan 1 2018, In: Holistic Nursing Practice. 32, 2, p. 81-89 9 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• A Conceptual Framework for Evaluating Information Technologies and Decision Support Systems for Bioterrorism Preparedness and Response

  Bravata, D. M., McDonald, K. M., Szeto, H., Smith, W. M., Rydzak, C. & Owens, D. K., Mar 2004, In: Medical Decision Making. 24, 2, p. 192-206 15 p.

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• A conceptual framework for understanding HIV risk behavior in the context of supporting fertility goals among HIV-serodiscordant couples

  Crankshaw, T. L., Matthews, L. T., Giddy, J., Kaida, A., Ware, N. C., Smit, J. A. & Bangsberg, D. R., Dec 2012, In: Reproductive Health Matters. 20, SUPPL. 39, p. 50-60 11 p.

  Research output: Contribution to journal › Article › peer-review
  41 Scopus citations

• A conceptual model for assessing quality of care for patients boarding in the emergency department: Structure-process-outcome

  Liu, S. W., Singer, S. J., Sun, B. C. & Camargo, C. A., Apr 2011, In: Academic Emergency Medicine. 18, 4, p. 430-435 6 p.

  Research output: Contribution to journal › Article › peer-review
  22 Scopus citations

• A Conceptual Model to Promote the Retention of Women with Physical Disabilities in Research

  Mood, L., Hassouneh, D. & Mcneff, E., Jul 1 2015, In: Public Health Nursing. 32, 4, p. 368-377 10 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• A conditional feedback loop regulates Ras activity through EphA2

  Macrae, M., Neve, R. M., Rodriguez-Viciana, P., Haqq, C., Yeh, J., Chen, C., Gray, J. W. & McCormick, F., Aug 2005, In: Cancer Cell. 8, 2, p. 111-118 8 p.

  Research output: Contribution to journal › Article › peer-review
  188 Scopus citations

• A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani

  Boitz, J. M. & Ullman, B., Jun 9 2006, In: Journal of Biological Chemistry. 281, 23, p. 16084-16089 6 p.

  Research output: Contribution to journal › Article › peer-review
  50 Scopus citations

• A conditional tetracycline-regulated increase in gamma amino butyric acid production near luteinizing hormone-releasing hormone nerve terminals disrupts estrous cyclicity in the rat

  Bilger, M., Heger, S., Brann, D. W., Paredes, A. & Ojeda, S. R., 2001, In: Endocrinology. 142, 5, p. 2102-2114 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  43 Scopus citations

• A conditioned stimulus decreases extracellular dopamine in the nucleus accumbens after the development of a learned taste aversion

  Mark, G. P., Blander, D. S. & Hoebel, B. G., Jun 14 1991, In: Brain research. 551, 1-2, p. 308-310 3 p.

  Research output: Contribution to journal › Article › peer-review
  162 Scopus citations

• A confocal laser microscopic study of enkephalin-immunoreactive appositions onto physiologically identified neurons in the rostral ventromedial medulla

  Mason, P., Back, S. A. & Fields, H. L., 1992, In: Journal of Neuroscience. 12, 10, p. 4023-4036 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  22 Scopus citations

• A conformation change in the extracellular domain that accompanies desensitization of acid-sensing ion channel (ASIC) 3

  Cushman, K. A., Marsh-Haffner, J., Adelman, J. P. & McCleskey, E. W., Apr 2007, In: Journal of General Physiology. 129, 4, p. 345-350 6 p.

  Research output: Contribution to journal › Article › peer-review
  53 Scopus citations

• A conjunctival lesion with histological features similar to large-cell acanthoma of the skin

  Ghazi, N. G., Patel, B. S., Olsakovsky, L. A., White, K., Patterson, J. W. & Carter, B., Oct 2010, In: Journal of cutaneous pathology. 37, 10, p. 1103-1106 4 p.

  Research output: Contribution to journal › Article › peer-review
  4 Scopus citations

• A consensus-based criterion standard for trauma center need

  Lerner, E. B., Willenbring, B. D., Pirrallo, R. G., Brasel, K. J., Cady, C. E., Colella, M. R., Cooper, A., Cushman, J. T., Gourlay, D. M., Jurkovich, G. J., Newgard, C. D., Salomone, J. P., Sasser, S. M., Shah, M. N., Swor, R. A. & Wang, S. C., Apr 2014, In: Journal of Trauma and Acute Care Surgery. 76, 4, p. 1157-1163 7 p.

  Research output: Contribution to journal › Article › peer-review
  36 Scopus citations

• A consensus on the diagnosis and treatment of acromegaly comorbidities: An update

  Giustina, A., Barkan, A., Beckers, A., Biermasz, N., Biller, B. M. K., Boguszewski, C., Bolanowski, M., Bonert, V., Bronstein, M. D., Casanueva, F. F., Clemmons, D., Colao, A., Ferone, D., Fleseriu, M., Frara, S., Gadelha, M. R., Ghigo, E., Gurnell, M., Heaney, A. P., Ho, K. & 25 others, Ioachimescu, A., Katznelson, L., Kelestimur, F., Kopchick, J., Krsek, M., Lamberts, S., Losa, M., Luger, A., Maffei, P., Marazuela, M., Mazziotti, G., Mercado, M., Mortini, P., Neggers, S., Pereira, A. M., Petersenn, S., Puig-Domingo, M., Salvatori, R., Shimon, I., Strasburger, C., Tsagarakis, S., van der Lely, A. J., Wass, J., Zatelli, M. C. & Melmed, S., Apr 1 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 4, p. E937-E946

  Research output: Contribution to journal › Article › peer-review
  94 Scopus citations

• A consensus statement on considerations for a successful CPOE implementation

  Ash, J. S., Stavri, P. Z. & Kuperman, G. J., May 2003, In: Journal of the American Medical Informatics Association. 10, 3, p. 229-234 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  182 Scopus citations

• A conservative approach to ceramic veneers: A case report

  Jurado, C. A., Watanabe, H., Tinoco, J. V., Valenzuela, H. U., Perez, G. G. & Tsujimoto, A., May 2020, In: Operative dentistry. 45, 3, p. 229-234 6 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• A conserved C-terminal 13-amino-acid motif of Gap1 Is Required for Gap1 Function and Necessary for the Biogenesis of a Serine-Rich Glycoprotein of Streptococcus parasanguinis

  Zhou, M., Peng, Z., Fives-Taylor, P. & Wu, H., Dec 2008, In: Infection and Immunity. 76, 12, p. 5624-5631 8 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• A conserved domain is crucial for acceptor substrate binding in a family of glucosyltransferases

  Zhu, F., Zhang, H. & Wu, H., 2015, In: Journal of bacteriology. 197, 3, p. 510-517 8 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• A conserved domain of previously unknown function in Gap1 mediates protein-protein interaction and is required for biogenesis of a serine-rich streptococcal adhesin

  Li, Y., Chen, Y., Huang, X., Zhou, M., Wu, R., Dong, S., Pritchard, D. G., Fives-Taylor, P. & Wu, H., Dec 2008, In: Molecular Microbiology. 70, 5, p. 1094-1104 11 p.

  Research output: Contribution to journal › Article › peer-review
  26 Scopus citations

• A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2 Å resolution

  Xu, Q., Abdubek, P., Astakhova, T., Axelrod, H. L., Bakolitsa, C., Cai, X., Carlton, D., Chen, C., Chiu, H. J., Chiu, M., Clayton, T., Das, D., Deller, M. C., Duan, L., Ellrott, K., Farr, C. L., Feuerhelm, J., Grant, J. C., Grzechnik, A., Han, G. W. & 31 others, Jaroszewski, L., Jin, K. K., Klock, H. E., Knuth, M. W., Kozbial, P., Krishna, S. S., Kumar, A., Marciano, D., McMullan, D., Miller, M. D., Morse, A. T., Nigoghossian, E., Nopakun, A., Okach, L., Puckett, C., Reyes, R., Sefcovic, N., Tien, H. J., Trame, C. B., Van Den Bedem, H., Weekes, D., Wooten, T., Yeh, A., Zhou, J., Hodgson, K. O., Wooley, J., Elsliger, M. A., Deacon, A. M., Godzik, A., Lesley, S. A. & Wilson, I. A., Oct 2010, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 66, 10, p. 1281-1286 6 p.

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• A conserved pathway that controls c-Myc protein stability through opposing phosphorylation events occurs in yeast

  Escamilla-Powers, J. R. & Sears, R. C., Feb 23 2007, In: Journal of Biological Chemistry. 282, 8, p. 5432-5442 11 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• A conserved PMK-1/p38 MAPK is required in Caenorhabditis elegans tissue-specific immune response to Yersinia pestis infection

  Bolz, D. D., Tenor, J. L. & Aballay, A., Apr 2 2010, In: Journal of Biological Chemistry. 285, 14, p. 10832-10840 9 p.

  Research output: Contribution to journal › Article › peer-review
  85 Scopus citations

• A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity

  Tenor, J. L. & Aballay, A., Jan 2008, In: EMBO Reports. 9, 1, p. 103-109 7 p.

  Research output: Contribution to journal › Article › peer-review
  131 Scopus citations

• A consortium approach to surgical education in a developing country: Educational needs assessment

  Cook, M., Howard, B. M., Yu, A., Grey, D., Hofmann, P. B., Moren, A. M., McHembe, M., Essajee, A., Mndeme, O., Peck, J. & Schecter, W. P., Nov 2015, In: JAMA Surgery. 150, 11, p. 1074-1078 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  15 Scopus citations

• A constitutively activating mutation alters the dynamics and energetics of a key conformational change in a ligand-free G protein-coupled receptor

  Tsukamoto, H. & Farrens, D. L., Sep 27 2013, In: Journal of Biological Chemistry. 288, 39, p. 28207-28216 10 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• A constitutive pan-hexose permease for the Plasmodium life cycle and transgenic models for screening of antimalarial sugar analogs

  Blume, M., Hliscs, M., Rodriguez-Contreras, D., Sanchez, M., Landfear, S., Lucius, R., Matuschewski, K. & Gupta, N., Apr 2011, In: FASEB Journal. 25, 4, p. 1218-1229 12 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations