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• 2018

  Synthesis, anti-cancer screening and tyrosyl-DNA phosphodiesterase 1 (Tdp1) inhibition activity of novel piperidinyl sulfamides

  Jun, J. H., Kumar, V., Dexheimer, T. S., Wedlich, I., Nicklaus, M. C., Pommier, Y. & Malhotra, S. V., Jan 1 2018, In: European Journal of Pharmaceutical Sciences. 111, p. 337-348 12 p.

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations

• Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter

  Provencher, B. A., Eshleman, A. J., Johnson, R. A., Shi, X., Kryatova, O., Nelson, J., Tian, J., Gonzalez, M., Meltzer, P. C. & Janowsky, A., Oct 25 2018, In: Journal of Medicinal Chemistry. 61, 20, p. 9121-9131 11 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Synthesis and Evaluation of New Bifunctional Chelators with Phosphonic Acid Arms for Gallium-68 Based PET Imaging in Melanoma

  Gai, Y., Sun, L., Lan, X., Zeng, D., Xiang, G. & Ma, X., Oct 17 2018, In: Bioconjugate Chemistry. 29, 10, p. 3483-3494 12 p.

  Research output: Contribution to journal › Article › peer-review
  15 Scopus citations

• Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia

  Jenkins, C., Luty, S. B., Maxson, J. E., Eide, C. A., Abel, M. L., Togiai, C., Nemecek, E. R., Bottomly, D., McWeeney, S. K., Wilmot, B., Loriaux, M., Chang, B. H. & Tyner, J. W., Jul 17 2018, In: Science signaling. 11, 539, eaao5617.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Systematic Analysis of Splice-Site-Creating Mutations in Cancer

  The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 270-281.e3

  Research output: Contribution to journal › Article › peer-review

  Open Access
  131 Scopus citations

• Systematic evaluation of a targeted gene capture sequencing panel for molecular diagnosis of retinitis pigmentosa

  Huang, H., Chen, Y., Chen, H., Ma, Y., Chiang, P. W., Zhong, J., Liu, X., Asan, Wu, J., Su, Y., Li, X., Deng, J., Huang, Y., Zhang, X., Li, Y., Fan, N., Wang, Y., Tang, L., Shen, J., Chen, M., & 6 othersZhang, X., Te, D., Banerjee, S., Liu, H., Qi, M. & Yi, X., Apr 2018, In: PloS one. 13, 4, e0185237.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Scopus citations

• Systematic Functional Annotation of Somatic Mutations in Cancer

  Ng, P. K. S., Li, J., Jeong, K. J., Shao, S., Chen, H., Tsang, Y. H., Sengupta, S., Wang, Z., Bhavana, V. H., Tran, R., Soewito, S., Minussi, D. C., Moreno, D., Kong, K., Dogruluk, T., Lu, H., Gao, J., Tokheim, C., Zhou, D. C., Johnson, A. M., & 20 othersZeng, J., Ip, C. K. M., Ju, Z., Wester, M., Yu, S., Li, Y., Vellano, C. P., Schultz, N., Karchin, R., Ding, L., Lu, Y., Cheung, L. W. T., Chen, K., Shaw, K. R., Meric-Bernstam, F., Scott, K. L., Yi, S., Sahni, N., Liang, H. & Mills, G. B., Mar 12 2018, In: Cancer Cell. 33, 3, p. 450-462.e10

  Research output: Contribution to journal › Article › peer-review

  Open Access
  126 Scopus citations

• Systematic review and meta-analysis of postexposure prophylaxis for crimean-congo hemorrhagic fever virus among healthcare workers

  Ergönül, Ö., Keske, Ş., Çeldir, M. G., Kara, İ. A., Pshenichnaya, N., Abuova, G., Blumberg, L. & Gönen, M., Sep 2018, In: Emerging infectious diseases. 24, 9, p. 1642-1648 7 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Systematic review for the 2017 ACC/AHA/AAPA/ABC/ ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults a report of the American College of Cardiology/American Heart Association Task Force on Clinical practice guidelines

  American College of Cardiology & American College of Cardiology/American Heart Association, Jun 2018, In: Hypertension. 71, 6, p. E116-E135

  Research output: Contribution to journal › Review article › peer-review
  89 Scopus citations

• Systematic review of health economic studies in cranial neurosurgery

  Ryu, W. H. A., Yang, M. M. H., Muram, S., Jacobs, W. B., Casha, S. & Riva-Cambrin, J., May 1 2018, In: Neurosurgical focus. 44, 5, E2.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Scopus citations

• Systematic Testing of Belief-Propagation Estimates for Absolute Free Energies in Atomistic Peptides and Proteins

  Donovan-Maiye, R. M., Langmead, C. J. & Zuckerman, D. M., Jan 9 2018, In: Journal of Chemical Theory and Computation. 14, 1, p. 426-443 18 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Systemic antibiotic use for nonbacterial dermatological conditions among referring providers

  Haynes, D., Lasarev, M. & Keller, J., May 2018, In: International Journal of Dermatology. 57, 5, p. 566-571 6 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Systemic arterial hypertension but not IGF-I treatment stimulates cardiomyocyte enlargement in neonatal lambs

  Wilburn, A. N., Giraud, G. D., Louey, S., Morgan, T., Gandhi, N. & Jonker, S. S., Nov 27 2018, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 5, p. R1038-R1048

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• Systemic complications of acromegaly and the impact of the current treatment landscape: An update

  Gadelha, M. R., Kasuki, L., Lim, D. S. T. & Fleseriu, M., Oct 10 2018, In: Endocrine reviews. 40, 1, p. 268-332 65 p.

  Research output: Contribution to journal › Review article › peer-review
  156 Scopus citations

• Systemic options for treating uveitis

  Arepalli, S. & Suhler, E. B., Oct 2018, In: Retina Today. 2018, October, p. 27-29 3 p.

  Research output: Contribution to journal › Article › peer-review

• Systems biology approach reveals a link between mTORC1 and G2/M DNA damage checkpoint recovery

  Hsieh, H. J., Zhang, W., Lin, S. H., Yang, W. H., Wang, J. Z., Shen, J., Zhang, Y., Lu, Y., Wang, H., Yu, J., Mills, G. B. & Peng, G., Dec 1 2018, In: Nature communications. 9, 1, 3982.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  21 Scopus citations

• T1-REDEEM: A randomized controlled trial to reduce diabetes distress among adults with type 1 diabetes

  Fisher, L., Hessler, D., Polonsky, W. H., Masharani, U., Guzman, S., Bowyer, V., Strycker, L., Ahmann, A., Basina, M., Blumer, I., Chloe, C., Kim, S., Peters, A. L., Shumway, M., Weihs, K. & Wu, P., Sep 1 2018, In: Diabetes care. 41, 9, p. 1862-1869 8 p.

  Research output: Contribution to journal › Article › peer-review
  44 Scopus citations

• T1 slope minus cervical lordosis (TS-CL), the cervical answer to PI-LL, defines cervical sagittal deformity in patients undergoing thoracolumbar osteotomy

  International Spine Study Group, Jun 1 2018, In: International Journal of Spine Surgery. 12, 3, p. 362-370 9 p.

  Research output: Contribution to journal › Article › peer-review
  18 Scopus citations

• T ₃ induces both markers of maturation and aging in pancreatic b-cells

  Aguayo-Mazzucato, C., Lee, T. B., Matzko, M., DiIenno, A., Rezanejad, H., Ramadoss, P., Scanlan, T., Zavacki, A. M., Larsen, P. R., Hollenberg, A., Colton, C., Sharma, A. & Bonner-Weir, S., Jul 2018, In: Diabetes. 67, 7, p. 1322-1331 10 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Tagmentation-based library preparation for low DNA input whole genome bisulfite sequencing

  Weichenhan, D., Wang, Q., Adey, A., Wolf, S., Shendure, J., Eils, R. & Plass, C., 2018, Methods in Molecular Biology. Humana Press Inc., p. 105-122 18 p. (Methods in Molecular Biology; vol. 1708).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  5 Scopus citations

• Tailored treatment of patients with hepatocellular carcinoma with portal vein invasion: Experience from a multidisciplinary hepatobiliary tumor program within a NCI comprehensive cancer center

  Walcott-Sapp, S., Naugler, S., Lim, J. Y., Wagner, J., Orloff, S. L., Farsad, K., Kolbeck, K. J., Kaufman, J., Maynard, E., Kristian Enestvedt, C., Mayo, S. C. & Billingsley, K., Dec 1 2018, In: Journal of Gastrointestinal Oncology. 9, 6, p. 1074-1083 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• "Taking a look under the hood"-imaging the phenotypic heterogeneity of familial hypercholesterolemia

  Shapiro, M. D. & Fazio, S., Sep 1 2018, In: Journal of clinical lipidology. 12, 5, p. 1095-1098 4 p.

  Research output: Contribution to journal › Editorial › peer-review
  1 Scopus citations

• Taking innovation to scale in primary care practices: The functions of health care extension

  Ono, S., Crabtree, B. F., Hemler, J. R., Balasubramanian, B. A., Edwards, S. T., Green, L. A., Kaufman, A., Solberg, L. I., Miller, W. L., Woodson, T. T., Sweeney, S. M. & Cohen, D. J., Feb 1 2018, In: Health Affairs. 37, 2, p. 222-230 9 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Taking Respect Seriously: Clinical Research and the Demands of Informed Consent

  Jansen, L. A., May 9 2018, In: Journal of Medicine and Philosophy (United Kingdom). 43, 3, p. 342-360 19 p.

  Research output: Contribution to journal › Review article › peer-review
  6 Scopus citations

• Tales from the Swamp: Influencing Legislation That Influences Our Practice

  Lindner, J. R. & Valentine, C. M., Dec 2018, In: Journal of the American Society of Echocardiography. 31, 12, p. A25-A26

  Research output: Contribution to journal › Editorial › peer-review

• Tandem column isolation of zirconium-89 from cyclotron bombarded yttrium targets using an automated fluidic platform: Anion exchange to hydroxamate resin columns

  O'Hara, M. J., Murray, N. J., Carter, J. C., Kellogg, C. M. & Link, J. M., Sep 14 2018, In: Journal of Chromatography A. 1567, p. 37-46 10 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Targeted Assessment of Enlargement of the Perivascular Space in Alzheimer's Disease and Vascular Dementia Subtypes Implicates Astroglial Involvement Specific to Alzheimer's Disease

  Boespflug, E. L., Simon, M. J., Leonard, E., Grafe, M., Woltjer, R., Silbert, L. C., Kaye, J. A. & Iliff, J. J., 2018, In: Journal of Alzheimer's Disease. 66, 4, p. 1587-1597 11 p.

  Research output: Contribution to journal › Article › peer-review
  34 Scopus citations

• Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc₁ and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis

  McConnell, E. V., Bruzual, I., Pou, S., Winter, R., Dodean, R. A., Smilkstein, M. J., Krollenbrock, A., Nilsen, A., Zakharov, L. N., Riscoe, M. K. & Doggett, J. S., Nov 9 2018, In: ACS Infectious Diseases. 4, 11, p. 1574-1584 11 p.

  Research output: Contribution to journal › Article › peer-review
  27 Scopus citations

• Targeting BCR-ABL-independent TKI resistance in chronic myeloid leukemia by mTOR and autophagy inhibition

  Mitchell, R., Hopcroft, L. E. M., Baquero, P., Allan, E. K., Hewit, K., James, D., Hamilton, G., Mukhopadhyay, A., O'Prey, J., Hair, A., Melo, J. V., Chan, E., Ryan, K. M., Maguer-Satta, V., Druker, B. J., Clark, R. E., Mitra, S., Herzyk, P., Nicolini, F. E., Salomoni, P., & 4 othersShanks, E., Calabretta, B., Holyoake, T. L. & Helgason, G. V., May 1 2018, In: Journal of the National Cancer Institute. 110, 5, p. 467-478 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  62 Scopus citations

• Targeting exercise interventions to patients with cancer in need: An individual patient data meta-analysis

  Sweegers, M. G., May, A. M., Chinapaw, M. J., Van Vulpen, J. K., Newton, R. U., Galvão, D. A., Aaronson, N. K., Stuiver, M. M., Jacobsen, P. B., Verdonck-De Leeuw, I. M., Steindorf, K., Irwin, M. L., Hayes, S., Griffith, K. A., Lucia, A., Herrero-Roman, F., Mesters, I., Van Weert, E., Knoop, H., Goedendorp, M. M., & 29 othersMutrie, N., Daley, A. J., McConnachie, A., Bohus, M., Thorsen, L., Schulz, K. H., Short, C. E., James, E. L., Plotnikoff, R. C., Arbane, G., Schmidt, M. E., Potthoff, K., Van Beurden, M., Oldenburg, H. S., Sonke, G. S., Van Harten, W. H., Garrod, R., Schmitz, K. H., Winters-Stone, K. M., Velthuis, M. J., Taaffe, D. R., Van Mechelen, W., Kersten, M. J., Nollet, F., Wenzel, J., Wiskemann, J., Brug, J., Courneya, K. S. & Buffart, L. M., Nov 1 2018, In: Journal of the National Cancer Institute. 110, 11, djy161.

  Research output: Contribution to journal › Review article › peer-review
  43 Scopus citations

• Targeting gamma secretase: Has progress moved up a Notch?

  Ileana Dumbrava, E. E., Mills, G. B. & Yap, T. A., Sep 1 2018, In: Annals of Oncology. 29, 9, p. 1889-1891 3 p.

  Research output: Contribution to journal › Editorial › peer-review
  3 Scopus citations

• Targeting Interleukin-23 in the Treatment of Noninfectious Uveitis

  Pepple, K. L. & Lin, P., Dec 2018, In: Ophthalmology. 125, 12, p. 1977-1983 7 p.

  Research output: Contribution to journal › Review article › peer-review
  44 Scopus citations

• Targeting myeloid-inflamed tumor with anti-CSF-1R antibody expands CD137+ effector T-cells in the murine model of pancreatic cancer

  Saung, M. T., Muth, S., Ding, D., Thomas, D. L., Blair, A. B., Tsujikawa, T., Coussens, L., Jaffee, E. M. & Zheng, L., Nov 13 2018, In: Journal for immunotherapy of cancer. 6, 1, 118.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  37 Scopus citations

• Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples

  Edwards V, D. K., Sweeney, D. T., Ho, H., Eide, C. A., Rofelty, A., Agarwal, A., Liu, S. Q., Danilov, A. V., Lee, P., Chantry, D., McWeeney, S. K., Druker, B. J., Tyner, J. W., Spurgeon, S. E. & Loriaux, M. M., May 15 2018, In: Oncotarget. 9, 37, p. 24576-24589 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  31 Scopus citations

• Targeting Pim Kinases and DAPK3 to Control Hypertension

  Carlson, D. A., Singer, M. R., Sutherland, C., Redondo, C., Alexander, L. T., Hughes, P. F., Knapp, S., Gurley, S. B., Sparks, M. A., MacDonald, J. A. & Haystead, T. A. J., Oct 18 2018, In: Cell Chemical Biology. 25, 10, p. 1195-1207.e32

  Research output: Contribution to journal › Article › peer-review

  Open Access
  9 Scopus citations

• Targeting the HIV-1 spike and coreceptor with Bi- and trispecific antibodies for single-component broad inhibition of entry

  Khan, S. N., Sok, D., Tran, K., Movsesyan, A., Dubrovskaya, V., Burton, D. R. & Wyatt, R. T., Sep 1 2018, In: Journal of virology. 92, 18, e00384.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  26 Scopus citations

• Targeting the Hsp40/Hsp70 chaperone axis as a novel strategy to treat aastration-resistant prostate cancer

  Moses, M. A., Kim, Y. S., Rivera-Marquez, G. M., Oshima, N., Watson, M. J., Beebe, K. E., Wells, C., Lee, S., Zuehlke, A. D., Shao, H., Bingman, W. E., Kumar, V., Malhotra, S. V., Weigel, N. L., Gestwicki, J. E., Trepel, J. B. & Neckers, L. M., Jul 15 2018, In: Cancer Research. 78, 14, p. 4022-4035 14 p.

  Research output: Contribution to journal › Article › peer-review
  74 Scopus citations

• Targeting the immune microenvironment in acute myeloid leukemia: A focus on T cell immunity

  Lamble, A. J. & Lind, E. F., Jun 13 2018, In: Frontiers in Oncology. 8, JUN, 213.

  Research output: Contribution to journal › Review article › peer-review
  63 Scopus citations

• Task delegation and burnout trade-offs among primary care providers and nurses in veterans affairs patient aligned care teams (VA PACTs)

  Edwards, S. T., Helfrich, C. D., Grembowski, D., Hulen, E., Clinton, W. L., Wood, G. B., Kim, L., Rose, D. E. & Stewart, G., Jan 1 2018, In: Journal of the American Board of Family Medicine. 31, 1, p. 83-93 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  31 Scopus citations

• Taste impairment in chronic rhinosinusitis

  Othieno, F., Schlosser, R. J., Rowan, N. R., Storck, K. A., Mattos, J. L., Smith, T. L. & Soler, Z. M., Jul 2018, In: International Forum of Allergy and Rhinology. 8, 7, p. 783-789 7 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• T-cell–mediated immune response to pneumococcal conjugate vaccine (PCV-13) and tetanus toxoid vaccine in patients with moderate-to-severe psoriasis during tofacitinib treatment

  Winthrop, K., Korman, N., Abramovits, W., Rottinghaus, S. T., Tan, H., Gardner, A., Mukwaya, G., Kaur, M. & Valdez, H., Jan 1 2018, (Accepted/In press) In: Journal of the American Academy of Dermatology.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• T Cells Dominate the Local Immune Response Induced by Intralesional IL-2 in Combination with Imiquimod and Retinoid for In-Transit Metastatic Melanoma

  Ogawa, H., Luxardi, G., Kirane, A., Kulkarni, R., Monjazeb, A. M., Cheng, M. Y., Ma, C. & Maverakis, E., Jun 2018, In: Journal of Investigative Dermatology. 138, 6, p. 1442-1445 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  5 Scopus citations

• Teaching and Learning Regional Anesthesia

  Woodworth, G., Ivie, R. & Maniker, R., Jan 1 2018, Education in Anesthesia: How to Deliver the Best Learning Experience. Cambridge University Press, p. 113-120 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

• Technetium Stabilization in Low-Solubility Sulfide Phases: A Review

  Pearce, C. I., Icenhower, J. P., Asmussen, R. M., Tratnyek, P. G., Rosso, K. M., Lukens, W. W. & Qafoku, N. P., Jun 21 2018, In: ACS Earth and Space Chemistry. 2, 6, p. 532-547 16 p.

  Research output: Contribution to journal › Review article › peer-review
  28 Scopus citations

• Technical refinements and outcomes of the modified anterior septal transplant

  Loyo, M., Markey, J. D., Gerecci, D., El Rassi, E., Li, R. J., Sullivan, C. B. & Wang, T. D., Jan 1 2018, In: JAMA Facial Plastic Surgery. 20, 1, p. 31-36 6 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Teledermatology and teledermatopathology as educational tools for international dermatology: a virtual grand rounds pilot curriculum

  Yeung, H., Sargen, M. R., Luk, K. M., Berry, E. G., Gurnee, E. A., Heuring, E., McMichael, J., Chen, S. C. & Stoff, B. K., Nov 2018, In: International Journal of Dermatology. 57, 11, p. 1358-1362 5 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Telemedical Diagnosis of Stage 4 and Stage 5 Retinopathy of Prematurity

  Patel, S. N., Singh, R., Jonas, K. E., Ostmo, S., Gupta, M. P., Campbell, J. P., Chiang, M., Chan, R. V. P., Chiang, M. F., Ostmo, S., Sonmez, K., Campbell, J. P., Chan, R. V. P., Jonas, K., Horowitz, J., Coki, O., Eccles, C. A., Sarna, L., Orlin, A., Berrocal, A., & 28 othersNegron, C., Drenser, K., Cumming, K., Osentoski, T., Check, T., Zajechowski, M., Lee, T., Kruger, E., McGovern, K., Simmons, C., Murthy, R., Galvis, S., Rotter, J., Chen, I., Li, X., Taylor, K., Roll, K., Kalpathy-Cramer, J., Erdogmus, D., Ioannidis, S., Martinez-Castellanos, M. A., Salinas-Longoria, S., Romero, R., Arriola, A., Olguin-Manriquez, F., Meraz-Gutierrez, M., Dulanto-Reinoso, C. M. & Montero-Mendoza, C., 2018, In: Ophthalmology Retina. 2, 1, p. 59-64 6 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Telemedicine coverage of intensive care units: A narrative review

  Vranas, K. C., Slatore, C. & Kerlin, M. P., Nov 2018, In: Annals of the American Thoracic Society. 15, 11, p. 1256-1264 9 p.

  Research output: Contribution to journal › Review article › peer-review
  29 Scopus citations

• Telmisartan therapy does not improve lymph node or adipose tissue fibrosis more than continued antiretroviral therapy alone

  Utay, N. S., Kitch, D. W., Yeh, E., Fichtenbaum, C. J., Lederman, M. M., Estes, J. D., Deleage, C., Magyar, C., Nelson, S. D., Klingman, K. L., Bastow, B., Luque, A. E., McComsey, G. A., Douek, D. C., Currier, J. S. & Lake, J. E., Jun 1 2018, In: Journal of Infectious Diseases. 217, 11, p. 1770-1781 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  16 Scopus citations

• Tempering the clinical effects of early myeloid-derived suppressor cell expansion in severe sepsis and septic shock

  Patel, J. J., Rosenthal, M. D., McClave, S. A. & Martindale, R. G., Mar 1 2018, In: American Journal of Respiratory and Critical Care Medicine. 197, 5, p. 677-678 2 p.

  Research output: Contribution to journal › Letter › peer-review
  7 Scopus citations