3He++ radio-frequency quadrupole accelerator for positron emission tomography

Ali E. Dabiri, William K. Hagan, Donald A. Swenson, Kenneth Krohn

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The feasibility of using a radio-frequency quadrupole (RFQ) accelerator to accelerate 3He++ for use in positron emission tomography (PET) is shown. The 3He++ RFQ is extremely lightweight in comparison to a cyclotron, but can nevertheless produce all four radioisotopes of interest (18F, 13N, 15O, and 11C) in more than adequate quantities. Due to the neutron-poor nature of 3He++, the desired positron emitters can be produced from naturally abundant target isotopes. In addition, target reactions and collisions with the accelerating structure produce relatively small numbers of neutrons compared to proton and deuteron systems. This yields two economic advantages. Enriched 13C, 15N, and 18O target materials are not required. Also, the shielding requirements are reduced considerably, and there is no need for radiation shielding around the accelerator. This reduced shielding results in a factor of 8 reduction in total facility shielding weight compared to a proton/deuteron cyclotron facility. The order of magnitude reduction in facility weight, the virtual elimination of the accelerator weight, and the relative lack of residual induced activity gives rise to the possibility of a radiopharmaceutical production system that is less expensive than present systems and may ultimately be transportable. Such a system could make PET imaging technology far more accessible geographically and financially than it is at present.

Original languageEnglish (US)
Pages (from-to)127-133
Number of pages7
JournalNuclear Technology
Volume92
Issue number1
StatePublished - Oct 1990
Externally publishedYes

Fingerprint

Positron emission tomography
Shielding
Particle accelerators
shielding
positrons
radio frequencies
accelerators
tomography
quadrupoles
Cyclotrons
cyclotrons
deuterons
Neutrons
Protons
Radiation shielding
neutrons
radiation shielding
protons
Positrons
Radioisotopes

ASJC Scopus subject areas

  • Nuclear Energy and Engineering

Cite this

Dabiri, A. E., Hagan, W. K., Swenson, D. A., & Krohn, K. (1990). 3He++ radio-frequency quadrupole accelerator for positron emission tomography. Nuclear Technology, 92(1), 127-133.

3He++ radio-frequency quadrupole accelerator for positron emission tomography. / Dabiri, Ali E.; Hagan, William K.; Swenson, Donald A.; Krohn, Kenneth.

In: Nuclear Technology, Vol. 92, No. 1, 10.1990, p. 127-133.

Research output: Contribution to journalArticle

Dabiri, AE, Hagan, WK, Swenson, DA & Krohn, K 1990, '3He++ radio-frequency quadrupole accelerator for positron emission tomography', Nuclear Technology, vol. 92, no. 1, pp. 127-133.
Dabiri, Ali E. ; Hagan, William K. ; Swenson, Donald A. ; Krohn, Kenneth. / 3He++ radio-frequency quadrupole accelerator for positron emission tomography. In: Nuclear Technology. 1990 ; Vol. 92, No. 1. pp. 127-133.
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