3. Phenylenhrine Hydrochloride

S. Martha Meyer, F. T. Fraunfelder

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

Phenylephrine hydrochloride is a potent, effective, relatively safe drug with few ocular side effects. Side effects from topical instillation are uncommon but include severe systemic cardiovascular effects with elevated blood pressure and stroke. Ten percent phenylephrine should be used with caution in patients with known cardiac disease, hypertension, aneurysms, long-standing insulin-dependent diabetes, or advanced arteriosclerosis. A 2.5% concentration is generally indicated for ophthalmic examination as well as for use in infants and in the elderly. Phenylephrine should not be used in patients with narrow-angle glaucoma, and it is also contraindicated in patients taking monoamine oxidase inhibitors or tricyclic antidepressants.

Original languageEnglish (US)
Pages (from-to)1177-1180
Number of pages4
JournalOphthalmology
Volume87
Issue number11
DOIs
StatePublished - Jan 1 1980

Keywords

  • anterior uveitis
  • mydriasis
  • phenylephrine hydrochloride
  • secondary glaucoma

ASJC Scopus subject areas

  • Ophthalmology

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