3. Phenylenhrine Hydrochloride

S. Martha Meyer; F. T. Fraunfelder

doi:10.1016/S0161-6420(80)35108-7

3. Phenylenhrine Hydrochloride

S. Martha Meyer, F. T. Fraunfelder

Ophthalmology

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Phenylephrine hydrochloride is a potent, effective, relatively safe drug with few ocular side effects. Side effects from topical instillation are uncommon but include severe systemic cardiovascular effects with elevated blood pressure and stroke. Ten percent phenylephrine should be used with caution in patients with known cardiac disease, hypertension, aneurysms, long-standing insulin-dependent diabetes, or advanced arteriosclerosis. A 2.5% concentration is generally indicated for ophthalmic examination as well as for use in infants and in the elderly. Phenylephrine should not be used in patients with narrow-angle glaucoma, and it is also contraindicated in patients taking monoamine oxidase inhibitors or tricyclic antidepressants.

Original language	English (US)
Pages (from-to)	1177-1180
Number of pages	4
Journal	Ophthalmology
Volume	87
Issue number	11
DOIs	https://doi.org/10.1016/S0161-6420(80)35108-7
State	Published - 1980

Keywords

anterior uveitis
mydriasis
phenylephrine hydrochloride
secondary glaucoma

ASJC Scopus subject areas

Ophthalmology

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10.1016/S0161-6420(80)35108-7

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title = "3. Phenylenhrine Hydrochloride",

abstract = "Phenylephrine hydrochloride is a potent, effective, relatively safe drug with few ocular side effects. Side effects from topical instillation are uncommon but include severe systemic cardiovascular effects with elevated blood pressure and stroke. Ten percent phenylephrine should be used with caution in patients with known cardiac disease, hypertension, aneurysms, long-standing insulin-dependent diabetes, or advanced arteriosclerosis. A 2.5% concentration is generally indicated for ophthalmic examination as well as for use in infants and in the elderly. Phenylephrine should not be used in patients with narrow-angle glaucoma, and it is also contraindicated in patients taking monoamine oxidase inhibitors or tricyclic antidepressants.",

keywords = "anterior uveitis, mydriasis, phenylephrine hydrochloride, secondary glaucoma",

author = "Meyer, {S. Martha} and Fraunfelder, {F. T.}",

note = "Funding Information: Supported in part by Research to Prevent Blindness, Inc.",

year = "1980",

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T1 - 3. Phenylenhrine Hydrochloride

AU - Meyer, S. Martha

AU - Fraunfelder, F. T.

N1 - Funding Information: Supported in part by Research to Prevent Blindness, Inc.

PY - 1980

Y1 - 1980

N2 - Phenylephrine hydrochloride is a potent, effective, relatively safe drug with few ocular side effects. Side effects from topical instillation are uncommon but include severe systemic cardiovascular effects with elevated blood pressure and stroke. Ten percent phenylephrine should be used with caution in patients with known cardiac disease, hypertension, aneurysms, long-standing insulin-dependent diabetes, or advanced arteriosclerosis. A 2.5% concentration is generally indicated for ophthalmic examination as well as for use in infants and in the elderly. Phenylephrine should not be used in patients with narrow-angle glaucoma, and it is also contraindicated in patients taking monoamine oxidase inhibitors or tricyclic antidepressants.

AB - Phenylephrine hydrochloride is a potent, effective, relatively safe drug with few ocular side effects. Side effects from topical instillation are uncommon but include severe systemic cardiovascular effects with elevated blood pressure and stroke. Ten percent phenylephrine should be used with caution in patients with known cardiac disease, hypertension, aneurysms, long-standing insulin-dependent diabetes, or advanced arteriosclerosis. A 2.5% concentration is generally indicated for ophthalmic examination as well as for use in infants and in the elderly. Phenylephrine should not be used in patients with narrow-angle glaucoma, and it is also contraindicated in patients taking monoamine oxidase inhibitors or tricyclic antidepressants.

KW - anterior uveitis

KW - mydriasis

KW - phenylephrine hydrochloride

KW - secondary glaucoma

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3. Phenylenhrine Hydrochloride

Abstract

Keywords

ASJC Scopus subject areas

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