3. Intraocular Reticulum Cell Sarcoma

Reticulum cell sarcoma is a form of malignant lymphoma that may arise systemically in the reticuloendothelial cells of the spleen or lymph nodes, or in the microglial cells of the brain. Intraocular reticulum cell sarcoma occurs most frequently in association with central nervous system reticulum cell sarcoma. Although relatively uncommon, this diagnosis should be considered in any adult patient with vitreitis or chorioretinitis of unknown etiology, particularly if the inflammation does not respond to the usual therapy. The diagnosis of reticulum cell sarcoma must be considered with any uveitis or vitreitis associated with neurologic symptoms. Prompt diagnosis is of importance because the tumor is radiosensitive, and improved visual acuity and survival may follow radiation therapy.