100% Adherence study: Educational workshops vs. video sessions to improve adherence among ART-naïve patients in Salvador, Brazil

Marcia Sampaio-Sa, Kimberly Page-Shafer, David R. Bangsberg, Jennifer Evans, Maria De Lourdes Dourado, Celia Teixeira, Eduardo M. Netto, Carlos Brites

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

We conducted a randomized trial to test an intervention aimed at increasing adherence to antiretroviral therapy (ART) among HIV-positive, ART-naïve patients in Salvador, Brazil. Participants (N = 107) were randomized to either educational workshops based on the information-motivation-behavioral skills model (n = 52) or a control video session (n = 55). Changes in self-reported ART adherence, viral load, CD4 cell counts and ART pharmacy records were measured periodically over 12 months. After 3-6 months, ART adherence (≥95%) was 77.8% in the workshop group and 85.7% in video group (as treated) and 53.8% and 65.5%, respectively, using intention-to-treat (ITT) analysis (both P > 0.05) At 9-12 months, ART adherence decreased to 73.7% in the workshop group and 79.1% in the video group (as treated) and 53.8% and 61.8% using ITT, respectively. No differences were found in self-reported adherence, viral load or pharmacy records between groups. We found that the educational workshop intervention does not increase adherence to ART.

Original languageEnglish (US)
Pages (from-to)S54-S62
JournalAIDS and Behavior
Volume12
Issue numberSUPPL. 1
DOIs
StatePublished - Jul 1 2008
Externally publishedYes

Keywords

  • AIDS
  • ART
  • Adherence
  • Brazil
  • HIV infection
  • Highly active antiretroviral therapy (HAART)

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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    Sampaio-Sa, M., Page-Shafer, K., Bangsberg, D. R., Evans, J., Dourado, M. D. L., Teixeira, C., Netto, E. M., & Brites, C. (2008). 100% Adherence study: Educational workshops vs. video sessions to improve adherence among ART-naïve patients in Salvador, Brazil. AIDS and Behavior, 12(SUPPL. 1), S54-S62. https://doi.org/10.1007/s10461-008-9414-0